L8I4F8 · L8I4F8_9CETA

  • Protein
    non-specific protein-tyrosine kinase
  • Status
    UniProtKB unreviewed (TrEMBL)
  • Amino acids
  • Protein existence
    Predicted
  • Annotation score
    5/5

Function

Catalytic activity

Features

Showing features for binding site.

110091002003004005006007008009001,000
TypeIDPosition(s)Description
Binding site457ATP (UniProtKB | ChEBI)

GO annotations

all annotationsall molecular functionvirus receptor activitydna bindingrna bindingcytoskeletal motor activitycatalytic activitygtpase activitystructural molecule activitytransporter activitycytoskeletal protein bindinglipid bindingcyclase activityantioxidant activityoxidoreductase activitytransferase activityhydrolase activitylyase activityisomerase activityligase activityprotein tag activitycargo receptor activityhistone bindingprotein folding chaperonetranslation regulator activitynutrient reservoir activityreceptor ligand activitymolecular transducer activitymolecular adaptor activitytoxin activitycell adhesion mediator activitymolecular function regulator activityvirus coreceptor activitycatalytic activity, acting on a proteincatalytic activity, acting on dnacatalytic activity, acting on rnamolecular carrier activitytranscription regulator activitygeneral transcription initiation factor activitymolecular sensor activitymolecular sequestering activityatp-dependent activityother molecular functionall biological processmitotic cell cyclecytokinesiscytoplasmic translationimmune system processmuscle system processcirculatory system processrenal system processrespiratory system processcarbohydrate metabolic processgeneration of precursor metabolites and energydna replicationdna repairdna recombinationchromatin organizationdna-templated transcriptionregulation of dna-templated transcriptiontrna metabolic processprotein foldingprotein glycosylationamino acid metabolic processmodified amino acid metabolic processlipid metabolic processvitamin metabolic processsulfur compound metabolic processintracellular protein transportnucleocytoplasmic transportautophagyinflammatory responsemitochondrion organizationcytoskeleton organizationmicrotubule-based movementperoxisome organizationlysosome organizationchromosome segregationcell adhesionestablishment or maintenance of cell polarityprogrammed cell deathphotosynthesismrna metabolic processsnrna metabolic processvesicle-mediated transportreproductive processdigestive system processsignalingcell differentiationprotein catabolic processextracellular matrix organizationregulatory ncrna-mediated gene silencingtelomere organizationcell junction organizationwound healingribosome biogenesiscilium organizationanatomical structure developmentcell motilitynervous system processendocrine processprotein maturationtransmembrane transportnucleobase-containing small molecule metabolic processhepaticobiliary system processmembrane organizationprotein-containing complex assemblycell wall organization or biogenesisnitrogen cycle metabolic processprotein localization to plasma membranedefense response to other organismdetoxificationmeiotic nuclear divisionmitotic nuclear divisionmitochondrial gene expressioncarbohydrate derivative metabolic processother biological processall cellular componentnuclear chromosomeextracellular regionextracellular spacecell wallnucleusnuclear envelopenucleoplasmchromosomenucleolusmitochondrionlysosomeendosomevacuoleperoxisomeendoplasmic reticulumgolgi apparatuslipid dropletmicrotubule organizing centercytosolribosomecytoskeletonplasma membraneciliumplastidthylakoidexternal encapsulating structureextracellular matrixcytoplasmic vesicleorganelleother cellular component
Cell color indicative of number of GO terms
AspectTerm
Cellular Componentcell cortex
Cellular Componentcytoskeleton
Cellular Componentfocal adhesion
Cellular Componentglutamatergic synapse
Cellular Componentlamellipodium
Cellular Componentnucleus
Cellular Componentperinuclear region of cytoplasm
Cellular Componentplasma membrane
Cellular Componentpostsynaptic density, intracellular component
Cellular Componentpresynapse
Molecular FunctionATP binding
Molecular Functionnon-membrane spanning protein tyrosine kinase activity
Biological Processbone resorption
Biological Processcellular response to fluid shear stress
Biological Processcellular response to retinoic acid
Biological Processchemokine-mediated signaling pathway
Biological Processcortical cytoskeleton organization
Biological Processendothelin receptor signaling pathway
Biological Processintegrin-mediated signaling pathway
Biological Processmarginal zone B cell differentiation
Biological Processnegative regulation of apoptotic process
Biological Processnegative regulation of bone mineralization
Biological Processnegative regulation of cell population proliferation
Biological Processnegative regulation of myeloid cell differentiation
Biological Processnegative regulation of potassium ion transport
Biological Processpositive regulation of actin filament polymerization
Biological Processpositive regulation of angiogenesis
Biological Processpositive regulation of B cell chemotaxis
Biological Processpositive regulation of cell population proliferation
Biological Processpositive regulation of cell-matrix adhesion
Biological Processpositive regulation of endothelial cell migration
Biological Processpositive regulation of ERK1 and ERK2 cascade
Biological Processpositive regulation of JNK cascade
Biological Processpositive regulation of neuron projection development
Biological Processpositive regulation of peptidyl-tyrosine phosphorylation
Biological Processpositive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction
Biological Processpositive regulation of ubiquitin-dependent protein catabolic process
Biological Processregulation of cell shape
Biological Processregulation of macrophage chemotaxis
Biological Processregulation of postsynaptic density assembly
Biological Processregulation of release of sequestered calcium ion into cytosol
Biological Processsignal complex assembly
Biological Processsprouting angiogenesis
Biological Processtumor necrosis factor-mediated signaling pathway
Biological Processvascular endothelial growth factor receptor signaling pathway

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    non-specific protein-tyrosine kinase
  • EC number

Gene names

    • ORF names
      M91_04142

Organism names

  • Taxonomic identifier
  • Organism
  • Strain
    • yakQH1
  • Taxonomic lineage
    Eukaryota > Metazoa > Chordata > Craniata > Vertebrata > Euteleostomi > Mammalia > Eutheria > Laurasiatheria > Artiodactyla > Ruminantia > Pecora > Bovidae > Bovinae > Bos

Accessions

  • Primary accession
    L8I4F8

Proteomes

Subcellular Location

Keywords

Interaction

Protein-protein interaction databases

Family & Domains

Features

Showing features for domain, region, compositional bias.

TypeIDPosition(s)Description
Domain39-359FERM
Domain425-683Protein kinase
Region701-725Disordered
Compositional bias707-725Pro residues

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    1,009
  • Mass (Da)
    115,626
  • Last updated
    2013-04-03 v1
  • Checksum
    8F8E99D5A7FBEAAF
MSGVSEALSRVKVGTLRRPEGPPEPMVVVPVDVEKEDVRILKVCFYGNSFNSGKNFKLVKCTVQTEIRDVIASILLSGRIGPNIQLADCYGLRLKHMKSDEIHWLHPLMTVGEVQDKYECLHVEAEWRYDLQVRYLPEDFMESLKEDKTTLLYFYQQLRNDYMQRYASKVSEGMALQLGCLELRRFFKDMPHNALDKKSNLELLEREVGLDLFFPKQMQENLKPKQFRKMIQQTFQQYASLREEECVMKFFNTLAGFANIDQETYRCELIQGWNITVDLVIGPKGIRQLTSQDAKPTCLAEFKQIKSIRCLPLEEGQAVLQLGIEGAPQSLSIKTSSLAEAENMADLVDGYCRLQGEHKGSLIIRTKKDGEKRNSLPQIPTLNLEARRPHLSESCSIESDIYAEIPDETLRRPGGPQYGIAREDVVLNHILGEGFFGEVYEGVYTNHKGEVINVAVKTCKKNCTLDNKEKFMSEAVIMKNLDHPHIVKLIGIIEEEPTWIIMELYPYGELGHYLERNKNSLKVLTLVLYSLQICKAMAYLESINCVHRDIAVRNILVASPECVKLGDFGLSRYIEDEEYYKASVTRLPIKWMSPESINFRRFTTASDVWMFAVCMWEILSFGKQPFFWLENKDVIGVLEKGDRLPKPDLCPPILYTLMTRCWDYDPSERPRFTELVCSLSDIYQMEKDIALEQERNARYRPPKILEPTAFQEPPPKPSRPKYRPPPQTNLLAPKLQFQVPEGLCASSPTLTSPMEYPSPVNSLHTPPLHRHNVFKRHSMREEDFVRPSSREEAQQLWEAERLKMRQLLDKQQKQMVEDYQWLRQEEKALDPMVYMNDKSPLTPEKEAGYTEFTAPPQKPPRLGAQSIQPTANLDRTDDLVYLNVMELVRAVLDLKNELCQLPPEGYVVVVKNVGLTLRKLIGSVDDLLPSLPSSSRTEIEGTQKLLNKDLAELINKMRLAQQNAVTSLSEECKRQMLTASHTLAVDAKNLLDAVDQAKVLANLARPLAE

Features

Showing features for compositional bias.

TypeIDPosition(s)Description
Compositional bias707-725Pro residues

Keywords

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
JH882068
EMBL· GenBank· DDBJ
ELR51078.1
EMBL· GenBank· DDBJ
Genomic DNA

Genome annotation databases

Similar Proteins

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