Direct detection of alternative open reading frames translation products in human significantly expands the proteome.Vanderperre B., Lucier J.-F., Motard J., Tremblay G., Vanderperre S., Wisztorski M., Salzet M., Boisvert F.-M., Roucou X.View abstractCited forNUCLEOTIDE SEQUENCECategoriesSequencesSourceUniProtKB unreviewed (TrEMBL)PubMedEurope PMCPLoS ONE 8:E70698-E70698 (2013)Cited in499+
Hypomethylation of the <i>RUNX2</i> Gene Is a New Potential Biomarker of Primary Osteoporosis in Men and Women.Yalaev B., Tyurin A., Akhiiarova K., Khusainova R.View abstractAnnotationHypomethylation of the RUNX2 Gene Is a New Potential Biomarker of Primary Osteoporosis in Men and Women.SourceGeneRif: 860PubMedEurope PMCInt J Mol Sci 25:7312-7312 (2024)Mapped to6
METTL3 Promotes Osteogenic Differentiation of Human Periodontal Ligament Stem Cells through IGF2BP1-Mediated Regulation of Runx2 Stability.Sun X., Meng X., Piao Y., Dong S., Dong Q.View abstractAnnotationMETTL3 Promotes Osteogenic Differentiation of Human Periodontal Ligament Stem Cells through IGF2BP1-Mediated Regulation of Runx2 Stability.SourceGeneRif: 860PubMedEurope PMCInt J Med Sci 21:664-673 (2024)Mapped to13
A synthetic, closed-looped gene circuit for the autonomous regulation of RUNX2 activity during chondrogenesis.Kaur G., Wu B., Murali S., Lanigan T., Coleman R.M.View abstractAnnotationA synthetic closed-looped gene circuit for the autonomous regulation of RUNX2 activity during chondrogenesis.SourceGeneRif: 860PubMedEurope PMCFASEB J 38:e23484-e23484 (2024)Mapped to6
Scopolamine regulates the osteogenic differentiation of human periodontal ligament stem cells through lactylation modification of RUNX2 protein.Wu Y., Gong P.View abstractAnnotationScopolamine regulates the osteogenic differentiation of human periodontal ligament stem cells through lactylation modification of RUNX2 protein.SourceGeneRif: 860PubMedEurope PMCPharmacol Res Perspect 12:e1169-e1169 (2024)Mapped to6
RUNX2 prompts triple negative breast cancer drug resistance through TGF- beta pathway regulating breast cancer stem cells.Lv F., Si W., Xu X., He X., Wang Y., Li Y., Li F.View abstractAnnotationRUNX2 prompts triple negative breast cancer drug resistance through TGF-beta pathway regulating breast cancer stem cells.SourceGeneRif: 860PubMedEurope PMCNeoplasia 48:100967-100967 (2024)Mapped to6
Circ_0027885 sponges miR-203-3p to regulate RUNX2 expression and alleviates osteoporosis progression.Fang S., Cao D., Wu Z., Chen J., Huang Y., Shen Y., Gao Z.View abstractAnnotationCirc_0027885 sponges miR-203-3p to regulate RUNX2 expression and alleviates osteoporosis progression.CategoriesFunctionSourceGeneRif: 860PubMedEurope PMCBMC Musculoskelet Disord 25:5-5 (2024)Mapped to6
Keratocystoma: A Distinctive Salivary Gland Neoplasm Characterized by RUNX2 Rearrangements.Bishop J.A., Nakaguro M., Urano M., Yamamoto Y., Utsumi Y., Li R., Weinreb I., Nagashima Y., Gangahar C.[...], Nagao T.View abstractAnnotationKeratocystoma: A Distinctive Salivary Gland Neoplasm Characterized by RUNX2 Rearrangements.SourceGeneRif: 860PubMedEurope PMCAm J Surg Pathol 48:317-328 (2024)Mapped to6
Polymorphisms in the Runx2 and osteocalcin genes affect BMD in postmenopausal women: a systematic review and meta-analysis.Sanyal S., Rajput S., Sadhukhan S., Rajender S., Mithal A., Chattopadhyay N.View abstractAnnotationPolymorphisms in the Runx2 and osteocalcin genes affect BMD in postmenopausal women: a systematic review and meta-analysis.SourceGeneRif: 860PubMedEurope PMCEndocrine 84:63-75 (2024)Mapped to7
Differences of RUNX2 gene promoter methylation and transcription level in ankylosing spondylitis.Wang F., Chen Y., Kong J., Xu S., Xu S., Shuai Z., Cai G., Pan F.View abstractAnnotationDifferences of RUNX2 gene promoter methylation and transcription level in ankylosing spondylitis.CategoriesFunctionSourceGeneRif: 860PubMedEurope PMCInt J Rheum Dis 26:2526-2533 (2023)Mapped to6
Preosteoclast plays a pathogenic role in syndesmophyte formation of ankylosing spondylitis through the secreted PDGFB - GRB2/ERK/RUNX2 pathway.Tang Y., Yang K., Liu Q., Ma Y., Zhu H., Tang K., Geng C., Xie J., Zhuo D.[...], Liu J.View abstractAnnotationPreosteoclast plays a pathogenic role in syndesmophyte formation of ankylosing spondylitis through the secreted PDGFB - GRB2/ERK/RUNX2 pathway.CategoriesFunctionSourceGeneRif: 860PubMedEurope PMCArthritis Res Ther 25:194-194 (2023)Mapped to22
HnRNP A1 Suppresses the Odontogenic Differentiation and the Inclusion of RUNX2 Exon 5 of Dental Mesenchymal Cells.Zhang Y., Huang J., Yan L., Jia R., Guo J.View abstractAnnotationHnRNP A1 Suppresses the Odontogenic Differentiation and the Inclusion of RUNX2 Exon 5 of Dental Mesenchymal Cells.CategoriesFunctionSourceGeneRif: 860PubMedEurope PMCFront Biosci (Landmark Ed) 28:139-139 (2023)Mapped to26
Functional consequences of C-terminal mutations in RUNX2.Thaweesapphithak S., Theerapanon T., Rattanapornsompong K., Intarak N., Kanpittaya P., Trachoo V., Porntaveetus T., Shotelersuk V.View abstractAnnotationFunctional consequences of C-terminal mutations in RUNX2.CategoriesFunctionSourceGeneRif: 860PubMedEurope PMCSci Rep 13:12202-12202 (2023)Mapped to6
Glutathione limits RUNX2 oxidation and degradation to regulate bone formation.Hu G., Yu Y., Sharma D., Pruett-Miller S.M., Ren Y., Zhang G.F., Karner C.M.View abstractAnnotationGlutathione limits RUNX2 oxidation and degradation to regulate bone formation.SourceGeneRif: 860PubMedEurope PMCJCI Insight 8:e166888-e166888 (2023)Mapped to25
Impact of genetic variations in the WNT family members and RUNX2 on dental and skeletal maturation: a cross-sectional study.Bitencourt Reis C.L., Nakane Matsumoto M.A., Baratto-Filho F., Scariot R., Sasso Stuani M.B., Lourenco Romano F., Della Coletta R., Silva Barroso de Oliveira D., Proff P.[...], Calvano Kuchler E.View abstractAnnotationImpact of genetic variations in the WNT family members and RUNX2 on dental and skeletal maturation: a cross-sectional study.CategoriesFunction, SequencesSourceGeneRif: 860PubMedEurope PMCHead Face Med 19:26-26 (2023)Mapped to7
Long non‑coding RNA SNHG5 promotes osteogenic differentiation of human periodontal ligament stem cells via mediating miR‑23b‑3p/Runx2 axis.Sun X., Li Z., Dong S., Dong Q.View abstractAnnotationLong non-coding RNA SNHG5 promotes osteogenic differentiation of human periodontal ligament stem cells via mediating miR-23b-3p/Runx2 axis.CategoriesFunction, ExpressionSourceGeneRif: 860PubMedEurope PMCInt J Med Sci 20:958-968 (2023)Mapped to6
Long non-coding RNA MALAT1 sponges miR-30c to promote the calcification of human vascular smooth muscle cells by regulating Runx2.Gong Y., Zhong Q., Xia Y., Wen Y., Gan H.View abstractAnnotationLong non-coding RNA MALAT1 sponges miR-30c to promote the calcification of human vascular smooth muscle cells by regulating Runx2.CategoriesFunction, ExpressionSourceGeneRif: 860PubMedEurope PMCRen Fail 45:2204953-2204953 (2023)Mapped to6
RUNX2 and Cancer.Lin T.C.View abstractAnnotationRUNX2 and Cancer.CategoriesNamesSourceGeneRif: 860PubMedEurope PMCInt J Mol Sci 24:7001-7001 (2023)Mapped to6
Abnormal mechanical stress on bicuspid aortic valve induces valvular calcification and inhibits Notch1/NICD/Runx2 signal.Li G., Shen N., Deng H., Wang Y., Kong G., Shi J., Dong N., Deng C.View abstractAnnotationAbnormal mechanical stress on bicuspid aortic valve induces valvular calcification and inhibits Notch1/NICD/Runx2 signal.CategoriesFunctionSourceGeneRif: 860PubMedEurope PMCPeerJ 11:e14950-e14950 (2023)Mapped to16
RUNX2 promotes the suppression of osteoblast function and enhancement of osteoclast activity by multiple myeloma cells.Huang B., Liu H., Chan S., Liu J., Gu J., Chen M., Kuang L., Li X., Zhang X., Li J.View abstractAnnotationRUNX2 promotes the suppression of osteoblast function and enhancement of osteoclast activity by multiple myeloma cells.CategoriesFunctionSourceGeneRif: 860PubMedEurope PMCMed Oncol 40:115-115 (2023)Mapped to11
Complement Cross Talks With H-K-ATPase to Upregulate Runx2 in Human Aortic Valve Interstitial Cells.Deng X.S., Meng X., Fullerton D., Stone M., Iguidbashian J., Jaggers J.View abstractAnnotationComplement Cross Talks With H-K-ATPase to Upregulate Runx2 in Human Aortic Valve Interstitial Cells.CategoriesFunction, ExpressionSourceGeneRif: 860PubMedEurope PMCJ Surg Res 286:118-126 (2023)Mapped to6
Crosstalk between protein kinase C alpha and transforming growth factor beta signaling mediated by Runx2 in intestinal epithelial cells.Li X., Kaur N., Albahrani M., Karpf A.R., Black A.R., Black J.D.View abstractAnnotationCrosstalk between protein kinase C alpha and transforming growth factor beta signaling mediated by Runx2 in intestinal epithelial cells.CategoriesFunctionSourceGeneRif: 860PubMedEurope PMCJ Biol Chem 299:103017-103017 (2023)Mapped to20
BMP4-SMAD1/5/9-RUNX2 pathway activation inhibits neurogenesis and oligodendrogenesis in Alzheimer's patients' iPSCs in senescence-related conditions.Nakatsu D., Kunishige R., Taguchi Y., Shinozaki-Narikawa N., Osaka K., Yokomizo K., Ishida M., Takei S., Yamasaki S.[...], Kano F.View abstractAnnotationBMP4-SMAD1/5/9-RUNX2 pathway activation inhibits neurogenesis and oligodendrogenesis in Alzheimer's patients' iPSCs in senescence-related conditions.CategoriesFunction, ExpressionSourceGeneRif: 860PubMedEurope PMCStem Cell Reports 18:688-705 (2023)Mapped to16
Extracellular PPM1A promotes mineralization of osteoblasts differentiation in ankylosing spondylitis via the FOXO1A-RUNX2 pathway.Weon S., Jo S., Nam B., Choi S.H., Park Y.S., Kim Y.G., Kim T.H.View abstractAnnotationExtracellular PPM1A promotes mineralization of osteoblasts differentiation in ankylosing spondylitis via the FOXO1A-RUNX2 pathway.CategoriesFunction, ExpressionSourceGeneRif: 860PubMedEurope PMCJ Cell Mol Med 27:650-658 (2023)Mapped to11
RUNX2 stabilization by long non-coding RNAs contributes to hypertrophic changes in human chondrocytes.Yoon D.S., Kim E.J., Cho S., Jung S., Lee K.M., Park K.H., Lee J.W., Kim S.H.View abstractAnnotationRUNX2 stabilization by long non-coding RNAs contributes to hypertrophic changes in human chondrocytes.CategoriesExpressionSourceGeneRif: 860PubMedEurope PMCInt J Biol Sci 19:13-33 (2023)Mapped to6