L7W0R0 · L7W0R0_9BACT
- ProteinTriosephosphate isomerase
- GenetpiA
- StatusUniProtKB unreviewed (TrEMBL)
- Amino acids262 (go to sequence)
- Protein existenceInferred from homology
- Annotation score3/5
Function
function
Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P).
Catalytic activity
- D-glyceraldehyde 3-phosphate = dihydroxyacetone phosphate
Pathway
Carbohydrate biosynthesis; gluconeogenesis.
Carbohydrate degradation; glycolysis; D-glyceraldehyde 3-phosphate from glycerone phosphate: step 1/1.
Features
Showing features for binding site, active site.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Binding site | 10-12 | substrate | ||||
Sequence: NWK | ||||||
Active site | 100 | Electrophile | ||||
Sequence: H | ||||||
Active site | 172 | Proton acceptor | ||||
Sequence: E | ||||||
Binding site | 178 | substrate | ||||
Sequence: G | ||||||
Binding site | 218 | substrate | ||||
Sequence: S | ||||||
Binding site | 239-240 | substrate | ||||
Sequence: GG |
GO annotations
Aspect | Term | |
---|---|---|
Cellular Component | cytosol | |
Molecular Function | triose-phosphate isomerase activity | |
Biological Process | gluconeogenesis | |
Biological Process | glyceraldehyde-3-phosphate biosynthetic process | |
Biological Process | glycerol catabolic process | |
Biological Process | glycolytic process |
Keywords
- Molecular function
- Biological process
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended nameTriosephosphate isomerase
- EC number
- Short namesTIM ; TPI
- Alternative names
Gene names
Organism names
- Taxonomic lineageBacteria > environmental samples
Accessions
- Primary accessionL7W0R0
Subcellular Location
Interaction
Subunit
Homodimer.
Structure
Sequence
- Sequence statusComplete
- Length262
- Mass (Da)27,991
- Last updated2013-04-03 v1
- Checksum33FB4253B61DF186