L7W0R0 · L7W0R0_9BACT

Function

function

Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P).

Catalytic activity

Pathway

Carbohydrate biosynthesis; gluconeogenesis.
Carbohydrate degradation; glycolysis; D-glyceraldehyde 3-phosphate from glycerone phosphate: step 1/1.

Features

Showing features for binding site, active site.

126220406080100120140160180200220240260
TypeIDPosition(s)Description
Binding site10-12substrate
Active site100Electrophile
Active site172Proton acceptor
Binding site178substrate
Binding site218substrate
Binding site239-240substrate

GO annotations

AspectTerm
Cellular Componentcytosol
Molecular Functiontriose-phosphate isomerase activity
Biological Processgluconeogenesis
Biological Processglyceraldehyde-3-phosphate biosynthetic process
Biological Processglycerol catabolic process
Biological Processglycolytic process

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    Triosephosphate isomerase
  • EC number
  • Short names
    TIM
    ; TPI
  • Alternative names
    • Triose-phosphate isomerase

Gene names

    • Name
      tpiA

Organism names

Accessions

  • Primary accession
    L7W0R0

Subcellular Location

Keywords

Interaction

Subunit

Homodimer.

Family & Domains

Sequence similarities

Belongs to the triosephosphate isomerase family.

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    262
  • Mass (Da)
    27,991
  • Last updated
    2013-04-03 v1
  • Checksum
    33FB4253B61DF186
MSRKPLMAGNWKMHLNHLEAIALVQKIAFLLKDDDYAAVDVAVLPPFTDIRSVQTLVEGDKLKIGYGAQDVSQHAAGAYTGEIAGHMLSKLGCGYVTVGHSERRTYHDETDAVVNAKAKAALENGLIPIVCVGEHLDVRQAGNHVAHVTDQLVGSLAGLTEEQMVNVVIAYEPVWAIGTGEVASPEDAQEVCHVIREWLGEQYGAGVAEQVRILYGGSVKSTNIAGIMAKADVDGALIGGASLDADEFATIVRYRLHPQVDA

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
JX649892
EMBL· GenBank· DDBJ
AGC72100.1
EMBL· GenBank· DDBJ
Genomic DNA

Similar Proteins

Disclaimer

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