L7VWB2 · L7VWB2_9BACT

Function

function

Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane.

Pathway

Cell wall biogenesis; peptidoglycan biosynthesis.

GO annotations

all annotationsall molecular functionvirus receptor activitydna bindingrna bindingcytoskeletal motor activitycatalytic activitygtpase activitystructural molecule activitytransporter activitycytoskeletal protein bindinglipid bindingcyclase activityantioxidant activityoxidoreductase activitytransferase activityhydrolase activitylyase activityisomerase activityligase activityprotein tag activitycargo receptor activityhistone bindingprotein folding chaperonetranslation regulator activitynutrient reservoir activityreceptor ligand activitymolecular transducer activitymolecular adaptor activitytoxin activitycell adhesion mediator activitymolecular function regulator activityvirus coreceptor activitycatalytic activity, acting on a proteincatalytic activity, acting on dnacatalytic activity, acting on rnamolecular carrier activitytranscription regulator activitygeneral transcription initiation factor activitymolecular sensor activitymolecular sequestering activityatp-dependent activityother molecular functionall biological processmitotic cell cyclecytokinesiscytoplasmic translationimmune system processmuscle system processcirculatory system processrenal system processrespiratory system processcarbohydrate metabolic processgeneration of precursor metabolites and energydna replicationdna repairdna recombinationchromatin organizationdna-templated transcriptionregulation of dna-templated transcriptiontrna metabolic processprotein foldingprotein glycosylationamino acid metabolic processmodified amino acid metabolic processlipid metabolic processvitamin metabolic processsulfur compound metabolic processintracellular protein transportnucleocytoplasmic transportautophagyinflammatory responsemitochondrion organizationcytoskeleton organizationmicrotubule-based movementperoxisome organizationlysosome organizationchromosome segregationcell adhesionestablishment or maintenance of cell polarityprogrammed cell deathphotosynthesismrna metabolic processsnrna metabolic processvesicle-mediated transportreproductive processdigestive system processsignalingcell differentiationprotein catabolic processextracellular matrix organizationregulatory ncrna-mediated gene silencingtelomere organizationcell junction organizationwound healingribosome biogenesiscilium organizationanatomical structure developmentcell motilitynervous system processendocrine processprotein maturationtransmembrane transportnucleobase-containing small molecule metabolic processhepaticobiliary system processmembrane organizationprotein-containing complex assemblycell wall organization or biogenesisnitrogen cycle metabolic processprotein localization to plasma membranedefense response to other organismdetoxificationmeiotic nuclear divisionmitotic nuclear divisionmitochondrial gene expressioncarbohydrate derivative metabolic processother biological processall cellular componentnuclear chromosomeextracellular regionextracellular spacecell wallnucleusnuclear envelopenucleoplasmchromosomenucleolusmitochondrionlysosomeendosomevacuoleperoxisomeendoplasmic reticulumgolgi apparatuslipid dropletmicrotubule organizing centercytosolribosomecytoskeletonplasma membraneciliumplastidthylakoidexternal encapsulating structureextracellular matrixcytoplasmic vesicleorganelleother cellular component
Cell color indicative of number of GO terms
AspectTerm
Cellular Componentplasma membrane
Molecular Functionlipid-linked peptidoglycan transporter activity
Biological Processcell wall organization
Biological Processlipid translocation
Biological Processpeptidoglycan biosynthetic process
Biological Processregulation of cell shape

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    Probable lipid II flippase MurJ

Gene names

    • Name
      murJ

Organism names

Accessions

  • Primary accession
    L7VWB2

Subcellular Location

Cell membrane
; Multi-pass membrane protein

Features

Showing features for transmembrane.

TypeIDPosition(s)Description
Transmembrane101-124Helical
Transmembrane151-171Helical
Transmembrane183-202Helical
Transmembrane208-231Helical
Transmembrane251-273Helical
Transmembrane285-309Helical
Transmembrane339-361Helical
Transmembrane381-400Helical
Transmembrane407-426Helical
Transmembrane432-454Helical
Transmembrane466-488Helical
Transmembrane508-529Helical

Keywords

Family & Domains

Sequence similarities

Belongs to the MurJ/MviN family.

Keywords

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    556
  • Mass (Da)
    58,597
  • Last updated
    2013-04-03 v1
  • Checksum
    B474760064F61650
MLVPTRPAHDAPPPAAAGGSMGKTALWLSLATFVSRILGLLREQVFAALLGAGFFGDAFTIAFRLPNLLRDLFAEGALSAAFQPAFQDARKQQGQPAAQHLANLVATCLLFVVGLLTVLGIVFAPQMVDGWAAGFAQVPGKAELTVQLTRIMMPFLLLVSLAALAMGMLNAERRFAPPALAPALFNLATVVTGLSLWVVGIGKTQGAAVAWAVATLCGGALQLGLQLVPLWKSGYRFRLAFDLGNPRLRMVLLAMAPATVGLAATQVNIYVSSRFASTEPGAASWLYYAFRLLQLPIGMFGVAVGTVALQRAADAASEADLQVALDGVRDTLRRGLRLVTFYSLPSAVMLYVLAEPVIGLIYQRGAFSAADTRATAEALRLYSLGLLCYAAVKVVVPVFYSLKLSRVAVISTVTTVLLSVLCNLLLHPLYGYRALAFSTSLGATWNLVSLLVVFRRRYGRLIGPEMGFALLQMVAASAVLGLILAVLSPLCLGQAATAEGLAQGHGQTLRAVVGLGLLGGAGGVGYLLLGGLFRLDEVAHVTGLVRRKLLRKKAGS

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
JX649879
EMBL· GenBank· DDBJ
AGC71661.1
EMBL· GenBank· DDBJ
Genomic DNA

Similar Proteins

Disclaimer

Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care. Our staff consists of biologists and biochemists that are not trained to give medical advice.
We'd like to inform you that we have updated our Privacy Notice to comply with Europe’s new General Data Protection Regulation (GDPR) that applies since 25 May 2018.
FeedbackHelp