L7VUA6 · L7VUA6_9BACT

Function

function

TetR is the repressor of the tetracycline resistance element; its N-terminal region forms a helix-turn-helix structure and binds DNA. Binding of tetracycline to TetR reduces the repressor affinity for the tetracycline resistance gene (tetA) promoter operator sites.

Features

Showing features for dna binding.

122120406080100120140160180200220
TypeIDPosition(s)Description
DNA binding33-52H-T-H motif

GO annotations

all annotationsall molecular functionvirus receptor activitydna bindingrna bindingcytoskeletal motor activitycatalytic activitygtpase activitystructural molecule activitytransporter activitycytoskeletal protein bindinglipid bindingcyclase activityantioxidant activityoxidoreductase activitytransferase activityhydrolase activitylyase activityisomerase activityligase activityprotein tag activitycargo receptor activityhistone bindingprotein folding chaperonetranslation regulator activitynutrient reservoir activityreceptor ligand activitymolecular transducer activitymolecular adaptor activitytoxin activitycell adhesion mediator activitymolecular function regulator activityvirus coreceptor activitycatalytic activity, acting on a proteincatalytic activity, acting on dnacatalytic activity, acting on rnamolecular carrier activitytranscription regulator activitygeneral transcription initiation factor activitymolecular sensor activitymolecular sequestering activityatp-dependent activityother molecular functionall biological processmitotic cell cyclecytokinesiscytoplasmic translationimmune system processmuscle system processcirculatory system processrenal system processrespiratory system processcarbohydrate metabolic processgeneration of precursor metabolites and energydna replicationdna repairdna recombinationchromatin organizationdna-templated transcriptionregulation of dna-templated transcriptiontrna metabolic processprotein foldingprotein glycosylationamino acid metabolic processmodified amino acid metabolic processlipid metabolic processvitamin metabolic processsulfur compound metabolic processintracellular protein transportnucleocytoplasmic transportautophagyinflammatory responsemitochondrion organizationcytoskeleton organizationmicrotubule-based movementperoxisome organizationlysosome organizationchromosome segregationcell adhesionestablishment or maintenance of cell polarityprogrammed cell deathphotosynthesismrna metabolic processsnrna metabolic processvesicle-mediated transportreproductive processdigestive system processsignalingcell differentiationprotein catabolic processextracellular matrix organizationregulatory ncrna-mediated gene silencingtelomere organizationcell junction organizationwound healingribosome biogenesiscilium organizationanatomical structure developmentcell motilitynervous system processendocrine processprotein maturationtransmembrane transportnucleobase-containing small molecule metabolic processhepaticobiliary system processmembrane organizationprotein-containing complex assemblycell wall organization or biogenesisnitrogen cycle metabolic processprotein localization to plasma membranedefense response to other organismdetoxificationmeiotic nuclear divisionmitotic nuclear divisionmitochondrial gene expressioncarbohydrate derivative metabolic processother biological processall cellular componentnuclear chromosomeextracellular regionextracellular spacecell wallnucleusnuclear envelopenucleoplasmchromosomenucleolusmitochondrionlysosomeendosomevacuoleperoxisomeendoplasmic reticulumgolgi apparatuslipid dropletmicrotubule organizing centercytosolribosomecytoskeletonplasma membraneciliumplastidthylakoidexternal encapsulating structureextracellular matrixcytoplasmic vesicleorganelleother cellular component
Cell color indicative of number of GO terms
AspectTerm
Molecular FunctionDNA binding
Molecular Functionmetal ion binding
Biological Processnegative regulation of DNA-templated transcription
Biological Processresponse to antibiotic

Keywords

Names & Taxonomy

Protein names

  • Submitted names
    • Transcriptional regulator, TetR family

Organism names

Accessions

  • Primary accession
    L7VUA6

Family & Domains

Features

Showing features for domain.

TypeIDPosition(s)Description
Domain10-70HTH tetR-type

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    221
  • Mass (Da)
    24,695
  • Last updated
    2013-04-03 v1
  • Checksum
    D78CD6C8A6055066
MAAKVKKRPPLSTDKVLRTALRMADKKGIEALSMRNLGQALKVEAMSIYNHVSGKEQLLDGLVELVVAELEPPTVGAEWRGAMRARAITAHRVLMQHPWATMLLVSRINVGPNMLRYIDRTVGCLREAGFSWAMADHAWNTLDAFTYGFTLQRLNFPLEPQQYAPAAQQFLPLIPVEQYPYMNGLSQEVIAGRHDGLQSLELGLEILLHGLDLLRDRGAAR

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
JX649860
EMBL· GenBank· DDBJ
AGC71029.1
EMBL· GenBank· DDBJ
Genomic DNA

Similar Proteins

Disclaimer

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