L7V5S0 · L7V5S0_MYCL1

Function

function

Catalyzes ATP-dependent phosphorylation of adenosylcobinamide and addition of GMP to adenosylcobinamide phosphate.

Catalytic activity

Pathway

Cofactor biosynthesis; adenosylcobalamin biosynthesis; adenosylcobalamin from cob(II)yrinate a,c-diamide: step 5/7.
Cofactor biosynthesis; adenosylcobalamin biosynthesis; adenosylcobalamin from cob(II)yrinate a,c-diamide: step 6/7.

Features

Showing features for binding site, active site.

TypeIDPosition(s)Description
Binding site7-14GTP (UniProtKB | ChEBI)
Binding site35-37GTP (UniProtKB | ChEBI)
Active site57GMP-histidine intermediate
Binding site58-61GTP (UniProtKB | ChEBI)
Binding site69GTP (UniProtKB | ChEBI)
Binding site88GTP (UniProtKB | ChEBI)

GO annotations

AspectTerm
Molecular Functionadenosylcobinamide kinase (ATP-specific) activity
Molecular Functionadenosylcobinamide kinase (GTP-specific) activity
Molecular FunctionATP binding
Molecular Functioncobinamide phosphate guanylyltransferase activity
Molecular FunctionGTP binding
Biological Processcobalamin biosynthetic process

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    Adenosylcobinamide kinase
  • EC number
  • Alternative names
    • Adenosylcobinamide-phosphate guanylyltransferase

Gene names

    • Name
      cobU
    • Ordered locus names
      MULP_03483

Organism names

Accessions

  • Primary accession
    L7V5S0

Proteomes

Family & Domains

Features

Showing features for region, compositional bias.

TypeIDPosition(s)Description
Region33-66Disordered
Compositional bias50-66Basic and acidic residues

Sequence similarities

Belongs to the CobU/CobP family.

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    186
  • Mass (Da)
    19,986
  • Last updated
    2013-04-03 v1
  • Checksum
    01599F332D3A7E98
MRTLVLGGIRSGKSRWAEETIADSLTPEQPVRYLASGPATDSDSAASQDWDQRVARHRDRRPGHWSTVETDDITTQLRQVPDTPTLVDDLGTWLTSAMDSHRAWEGGSPPAALQDTIDDMLAAVGEFGSTLVLVSPEVGLTVVPATASGRRFADELGTLNQRMAALCDRVVLVVAGQAVPIKPSRA

Features

Showing features for compositional bias.

TypeIDPosition(s)Description
Compositional bias50-66Basic and acidic residues

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
CP003899
EMBL· GenBank· DDBJ
AGC63161.1
EMBL· GenBank· DDBJ
Genomic DNA

Genome annotation databases

Similar Proteins

Disclaimer

Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care. Our staff consists of biologists and biochemists that are not trained to give medical advice.
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