L7V1H0 · L7V1H0_MYCL1

Function

function

Fluoride-specific ion channel. Important for reducing fluoride concentration in the cell, thus reducing its toxicity.

Catalytic activity

Activity regulation

Na+ is not transported, but it plays an essential structural role and its presence is essential for fluoride channel function.

Features

Showing features for binding site.

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TypeIDPosition(s)Description
Binding site75Na+ (UniProtKB | ChEBI); structural
Binding site78Na+ (UniProtKB | ChEBI); structural

GO annotations

AspectTerm
Cellular Componentplasma membrane
Molecular Functionfluoride channel activity
Molecular Functionmetal ion binding
Biological Processcellular detoxification of fluoride

Keywords

Names & Taxonomy

Protein names

  • Recommended name
    Fluoride-specific ion channel FluC

Gene names

    • Name
      crcB
    • Synonyms
      fluC
    • Ordered locus names
      MULP_01724

Organism names

Accessions

  • Primary accession
    L7V1H0

Proteomes

Subcellular Location

Cell membrane
; Multi-pass membrane protein

Features

Showing features for transmembrane.

TypeIDPosition(s)Description
Transmembrane6-26Helical
Transmembrane38-59Helical
Transmembrane65-85Helical
Transmembrane97-121Helical

Keywords

Family & Domains

Sequence similarities

Belongs to the fluoride channel Fluc/FEX (TC 1.A.43) family.

Keywords

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    124
  • Mass (Da)
    13,105
  • Last updated
    2013-04-03 v1
  • Checksum
    9C71A1BAAD2D9936
MTAGTVVVWMGVMVIGGLGSTLRFLVDRTIARRMARTFPFGTFAVNVSGAALLGFLAGLALSRDAALLAGTAFVGAYTTFSTWMLETQRLSEERQMWVALANIGLSVLAGLGAALLGHWIAQLL

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
CP003899
EMBL· GenBank· DDBJ
AGC61651.1
EMBL· GenBank· DDBJ
Genomic DNA

Genome annotation databases

Similar Proteins

Disclaimer

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