L7RXH5 · L7RXH5_HUMAN
- ProteinMitogen-activated protein kinase
- GeneMAPK3
- StatusUniProtKB unreviewed (TrEMBL)
- Organism
- Amino acids379 (go to sequence)
- Protein existenceEvidence at transcript level
- Annotation score5/5
Function
Catalytic activity
- ATP + L-seryl-[protein] = ADP + H+ + O-phospho-L-seryl-[protein]
Cofactor
Activity regulation
Activated by threonine and tyrosine phosphorylation.
Features
Showing features for binding site.
GO annotations
Keywords
- Molecular function
- Ligand
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended nameMitogen-activated protein kinase
- EC number
Gene names
Organism names
- Organism
- Taxonomic lineageEukaryota > Metazoa > Chordata > Craniata > Vertebrata > Euteleostomi > Mammalia > Eutheria > Euarchontoglires > Primates > Haplorrhini > Catarrhini > Hominidae > Homo
Accessions
- Primary accessionL7RXH5
Organism-specific databases
Subcellular Location
UniProt Annotation
GO Annotation
Disease & Variants
Organism-specific databases
Expression
Gene expression databases
Interaction
Protein-protein interaction databases
Structure
Family & Domains
Features
Showing features for region, domain.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Region | 1-26 | Disordered | ||||
Sequence: MAAAAAQGGGGGEPRRTEGVGPGVPG | ||||||
Domain | 42-330 | Protein kinase | ||||
Sequence: YTQLQYIGEGAYGMVSSAYDHVRKTRVAIKKISPFEHQTYCQRTLREIQILLRFRHENVIGIRDILRASTLEAMRDVYIVQDLMETDLYKLLKSQQLSNDHICYFLYQILRGLKYIHSANVLHRDLKPSNLLINTTCDLKICDFGLARIADPEHDHTGFLTEYVATRWYRAPEIMLNSKGYTKSIDIWSVGCILAEMLSNRPIFPGKHYLDQLNHILGILGSPSQEDLNCIINMKARNYLQSLPSKTKVAWAKLFPKSDSKALDLLDRMLTFNPNKRITVEEALAHPYL |
Sequence similarities
Phylogenomic databases
Family and domain databases
Sequence
- Sequence statusComplete
- Length379
- Mass (Da)43,136
- Last updated2013-04-03 v1
- ChecksumE6020CE413EC41F7
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
JX512450 EMBL· GenBank· DDBJ | AGC09597.1 EMBL· GenBank· DDBJ | Genomic DNA | ||
KJ534878 EMBL· GenBank· DDBJ | AHW56518.1 EMBL· GenBank· DDBJ | mRNA |