L7C833 · L7C833_RHOBT
- ProteinDNA-directed RNA polymerase subunit beta
- GenerpoB
- StatusUniProtKB unreviewed (TrEMBL)
- Organism
- Amino acids1240 (go to sequence)
- Protein existenceInferred from homology
- Annotation score2/5
Function
function
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
Catalytic activity
- RNA(n) + a ribonucleoside 5'-triphosphate = RNA(n+1) + diphosphate
GO annotations
Aspect | Term | |
---|---|---|
Cellular Component | DNA-directed RNA polymerase complex | |
Molecular Function | DNA binding | |
Molecular Function | DNA-directed 5'-3' RNA polymerase activity | |
Molecular Function | ribonucleoside binding | |
Biological Process | DNA-templated transcription |
Keywords
- Molecular function
- Biological process
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended nameDNA-directed RNA polymerase subunit beta
- EC number
- Short namesRNAP subunit beta
- Alternative names
Gene names
Organism names
- Organism
- Strain
- Taxonomic lineageBacteria > Planctomycetota > Planctomycetia > Pirellulales > Pirellulaceae > Rhodopirellula
Accessions
- Primary accessionL7C833
Proteomes
Subcellular Location
UniProt Annotation
GO Annotation
Keywords
- Cellular component
Interaction
Subunit
The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.
Structure
Family & Domains
Features
Showing features for domain.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Domain | 29-127 | RNA polymerase beta subunit protrusion | |||
Domain | 129-448 | RNA polymerase beta subunit protrusion | |||
Domain | 296-403 | RNA polymerase Rpb2 | |||
Domain | 462-530 | RNA polymerase Rpb2 | |||
Domain | 540-605 | DNA-directed RNA polymerase beta subunit external 1 | |||
Domain | 614-1160 | DNA-directed RNA polymerase subunit 2 hybrid-binding | |||
Domain | 1162-1236 | RNA polymerase Rpb2 | |||
Sequence similarities
Belongs to the RNA polymerase beta chain family.
Family and domain databases
Sequence
- Sequence statusComplete
- Length1,240
- Mass (Da)138,007
- Last updated2013-03-06 v1
- MD5 Checksum9889C39FEF7682BBA0A9A14527314164
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
AMWG01000179 EMBL· GenBank· DDBJ | ELP29832.1 EMBL· GenBank· DDBJ | Genomic DNA |