K9M5U0 · K9M5U0_HUMAN
- ProteinNADH-ubiquinone oxidoreductase chain 1
- GeneND1
- StatusUniProtKB unreviewed (TrEMBL)
- Organism
- Amino acids318 (go to sequence)
- Protein existenceInferred from homology
- Annotation score2/5
Function
Catalytic activity
- a ubiquinone + NADH + 5 H+(in) = a ubiquinol + NAD+ + 4 H+(out)
a ubiquinone RHEA-COMP:9565 + CHEBI:57945 + 5 H+ (in)CHEBI:15378= a ubiquinol RHEA-COMP:9566 + CHEBI:57540 + 4 H+ (out)CHEBI:15378
GO annotations
Aspect | Term | |
---|---|---|
Cellular Component | mitochondrial inner membrane | |
Molecular Function | NADH dehydrogenase (ubiquinone) activity |
Keywords
- Molecular function
- Biological process
- Ligand
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended nameNADH-ubiquinone oxidoreductase chain 1
- EC number
Gene names
Encoded on
- Mitochondrion
Organism names
- Organism
- Taxonomic lineageEukaryota > Metazoa > Chordata > Craniata > Vertebrata > Euteleostomi > Mammalia > Eutheria > Euarchontoglires > Primates > Haplorrhini > Catarrhini > Hominidae > Homo
Accessions
- Primary accessionK9M5U0
Subcellular Location
UniProt Annotation
GO Annotation
Membrane ; Multi-pass membrane protein
Mitochondrion inner membrane ; Multi-pass membrane protein
Features
Showing features for transmembrane.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Transmembrane | 6-23 | Helical | |||
Transmembrane | 68-86 | Helical | |||
Transmembrane | 98-119 | Helical | |||
Transmembrane | 140-160 | Helical | |||
Transmembrane | 220-243 | Helical | |||
Transmembrane | 255-273 | Helical | |||
Transmembrane | 293-314 | Helical | |||
Keywords
- Cellular component
PTM/Processing
Proteomic databases
Structure
Sequence
- Sequence statusComplete
- Length318
- Mass (Da)35,634
- Last updated2013-03-06 v1
- MD5 Checksum2CD7F77BBAECDBC0AE48E715C3713D06
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
JX413020 EMBL· GenBank· DDBJ | AFQ98554.1 EMBL· GenBank· DDBJ | Genomic DNA | ||
JX669327 EMBL· GenBank· DDBJ | AFV55964.1 EMBL· GenBank· DDBJ | Genomic DNA | ||
MK860671 EMBL· GenBank· DDBJ | QEG54713.1 EMBL· GenBank· DDBJ | Genomic DNA |