K9GLJ7 · K9GLJ7_9PROT
- ProteinRibonuclease PH
- Generph
- StatusUniProtKB unreviewed (TrEMBL)
- Organism
- Amino acids239 (go to sequence)
- Protein existenceInferred from homology
- Annotation score3/5
Function
function
Phosphorolytic 3'-5' exoribonuclease that plays an important role in tRNA 3'-end maturation. Removes nucleotide residues following the 3'-CCA terminus of tRNAs; can also add nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates, but this may not be physiologically important. Probably plays a role in initiation of 16S rRNA degradation (leading to ribosome degradation) during starvation.
Catalytic activity
- tRNA(n+1) + phosphate = tRNA(n) + a ribonucleoside 5'-diphosphate
Features
Showing features for binding site.
GO annotations
Aspect | Term | |
---|---|---|
Molecular Function | 3'-5'-RNA exonuclease activity | |
Molecular Function | tRNA binding | |
Molecular Function | tRNA nucleotidyltransferase activity | |
Biological Process | rRNA catabolic process | |
Biological Process | rRNA processing | |
Biological Process | tRNA processing |
Keywords
- Molecular function
- Biological process
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended nameRibonuclease PH
- EC number
- Short namesRNase PH
- Alternative names
Gene names
Organism names
- Organism
- Strain
- Taxonomic lineageBacteria > Pseudomonadota > Alphaproteobacteria > Rhodospirillales > Novispirillaceae > Caenispirillum
Accessions
- Primary accessionK9GLJ7
Proteomes
Interaction
Subunit
Homohexameric ring arranged as a trimer of dimers.
Protein-protein interaction databases
Structure
Family & Domains
Features
Showing features for domain.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Domain | 11-140 | Exoribonuclease phosphorolytic | ||||
Sequence: LRPVTLEPGFAKHAEGSCFIRFGDTHVLCTASVDERVPPWLRGQGRGWVTAEYGMLPRATHTRGDREAARGKQSGRTQEIQRLIGRSLRSVVNLKGMGEMQIKVDCDVIQADGGTRCASITGGYVALYQA | ||||||
Domain | 159-223 | Exoribonuclease phosphorolytic | ||||
Sequence: VAAVSCGIYKGTPVLDLDYAEDSSADADSNFVMTAKGLIVEVQTTAEEHPFEQSQLTAMMDLATA |
Sequence similarities
Belongs to the RNase PH family.
Phylogenomic databases
Family and domain databases
Sequence
- Sequence statusComplete
- Length239
- Mass (Da)25,591
- Last updated2013-02-06 v1
- ChecksumF98952950C5CA979
Keywords
- Technical term
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
ANHY01000022 EMBL· GenBank· DDBJ | EKV26885.1 EMBL· GenBank· DDBJ | Genomic DNA |