K9GJP0 · K9GJP0_9PROT
- ProteinRelease factor glutamine methyltransferase
- GeneprmC
- StatusUniProtKB unreviewed (TrEMBL)
- Organism
- Amino acids284 (go to sequence)
- Protein existenceInferred from homology
- Annotation score2/5
Function
function
Methylates the class 1 translation termination release factors RF1/PrfA and RF2/PrfB on the glutamine residue of the universally conserved GGQ motif.
Catalytic activity
- L-glutaminyl-[peptide chain release factor] + S-adenosyl-L-methionine = N5-methyl-L-glutaminyl-[peptide chain release factor] + S-adenosyl-L-homocysteine + H+
Features
Showing features for binding site.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Binding site | 124-128 | S-adenosyl-L-methionine (UniProtKB | ChEBI) | |||
Binding site | 147 | S-adenosyl-L-methionine (UniProtKB | ChEBI) | |||
Binding site | 176 | S-adenosyl-L-methionine (UniProtKB | ChEBI) | |||
Binding site | 190 | S-adenosyl-L-methionine (UniProtKB | ChEBI) | |||
Binding site | 190-193 | substrate | |||
GO annotations
Aspect | Term | |
---|---|---|
Molecular Function | nucleic acid binding | |
Molecular Function | protein-(glutamine-N5) methyltransferase activity | |
Molecular Function | protein-glutamine N-methyltransferase activity | |
Biological Process | peptidyl-glutamine methylation |
Keywords
- Molecular function
- Ligand
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended nameRelease factor glutamine methyltransferase
- EC number
- Short namesRF MTase
- Alternative names
Gene names
Organism names
- Organism
- Strain
- Taxonomic lineageBacteria > Pseudomonadota > Alphaproteobacteria > Rhodospirillales > Novispirillaceae > Caenispirillum
Accessions
- Primary accessionK9GJP0
Proteomes
Interaction
Protein-protein interaction databases
Structure
Family & Domains
Features
Showing features for domain.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Domain | 9-78 | Release factor glutamine methyltransferase N-terminal | |||
Domain | 106-194 | Methyltransferase small | |||
Sequence similarities
Belongs to the protein N5-glutamine methyltransferase family. PrmC subfamily.
Phylogenomic databases
Family and domain databases
Sequence
- Sequence statusComplete
- Length284
- Mass (Da)30,122
- Last updated2013-02-06 v1
- MD5 Checksum528E05F4262723AFEE5953065015B18C
Keywords
- Technical term
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
ANHY01000036 EMBL· GenBank· DDBJ | EKV26170.1 EMBL· GenBank· DDBJ | Genomic DNA |