K9GJM8 · K9GJM8_9PROT

  • Protein
    4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase (flavodoxin)
  • Gene
    ispG
  • Status
    UniProtKB unreviewed (TrEMBL)
  • Amino acids
  • Protein existence
    Inferred from homology
  • Annotation score
    3/5

Function

function

Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate.

Caution

The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

Catalytic activity

Cofactor

[4Fe-4S] cluster (UniProtKB | Rhea| CHEBI:49883 )

Note: Binds 1 [4Fe-4S] cluster.

Pathway

Isoprenoid biosynthesis; isopentenyl diphosphate biosynthesis via DXP pathway; isopentenyl diphosphate from 1-deoxy-D-xylulose 5-phosphate: step 5/6.

Features

Showing features for binding site.

TypeIDPosition(s)Description
Binding site273[4Fe-4S] cluster (UniProtKB | ChEBI)
Binding site276[4Fe-4S] cluster (UniProtKB | ChEBI)
Binding site308[4Fe-4S] cluster (UniProtKB | ChEBI)
Binding site315[4Fe-4S] cluster (UniProtKB | ChEBI)

GO annotations

AspectTerm
Molecular Function4 iron, 4 sulfur cluster binding
Molecular Function4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase activity (ferredoxin)
Molecular Function4-hydroxy-3-methylbut-2-enyl-diphosphate synthase activity (flavodoxin)
Molecular Functioniron ion binding
Biological Processisopentenyl diphosphate biosynthetic process, methylerythritol 4-phosphate pathway
Biological Processterpenoid biosynthetic process

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase (flavodoxin)
  • EC number
  • Alternative names
    • 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate synthase

Gene names

    • Name
      ispG
    • ORF names
      C882_2874

Organism names

  • Taxonomic identifier
  • Strain
    • AK4
  • Taxonomic lineage
    Bacteria > Pseudomonadota > Alphaproteobacteria > Rhodospirillales > Novispirillaceae > Caenispirillum

Accessions

  • Primary accession
    K9GJM8

Proteomes

Interaction

Protein-protein interaction databases

Family & Domains

Sequence similarities

Belongs to the IspG family.

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    377
  • Mass (Da)
    40,211
  • Last updated
    2013-02-06 v1
  • Checksum
    103879EE244A00B8
MSSVRPYRQILRRPSRQIMVGSVPVGGDAPISVQSMTNTKTTDVAGTVDQIRRLEEAGADIVRVSCPDEESTAAFKDIVRHSNVPLVADIHFHYKRALEAADAGAACLRINPGNIGSEDRVREVVRAAKANGCSIRIGVNAGSLERDLLEQYGEPCPEAMVASAQRHMAVLQDNDFQEFKISVKASDVFLAVAAYMQLAEACDYPLHLGITEAGGLRGGTVKSAVGMGNLLWAGIGDTIRVSLSADPVEEIKVGFEILKSLGLRHRGVRVISCPSCARQGFDVIKTVETLEERLAHIATPMTLSIIGCVVNGPGEARETDIGLTGGGSGSHMVYVSGVKDHTINDETMVEHLVSMVEKKAAEIEAAKAEEAEAPAAE

Keywords

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
ANHY01000036
EMBL· GenBank· DDBJ
EKV26165.1
EMBL· GenBank· DDBJ
Genomic DNA

Genome annotation databases

Similar Proteins

Disclaimer

Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care. Our staff consists of biologists and biochemists that are not trained to give medical advice.
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