K8YBC6 · K8YBC6_9LEPT
- ProteinPolyphosphate kinase
- Geneppk
- StatusUniProtKB unreviewed (TrEMBL)
- Amino acids710 (go to sequence)
- Protein existenceInferred from homology
- Annotation score3/5
Function
function
Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP).
Catalytic activity
- [phosphate](n) + ATP = [phosphate](n+1) + ADP
Cofactor
Features
Showing features for binding site, active site.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Binding site | 71 | ATP (UniProtKB | ChEBI) | |||
Binding site | 402 | Mg2+ (UniProtKB | ChEBI) | |||
Binding site | 432 | Mg2+ (UniProtKB | ChEBI) | |||
Active site | 462 | Phosphohistidine intermediate | |||
Binding site | 495 | ATP (UniProtKB | ChEBI) | |||
Binding site | 591 | ATP (UniProtKB | ChEBI) | |||
Binding site | 619 | ATP (UniProtKB | ChEBI) | |||
GO annotations
Aspect | Term | |
---|---|---|
Cellular Component | polyphosphate kinase complex | |
Molecular Function | ATP binding | |
Molecular Function | metal ion binding | |
Molecular Function | polyphosphate kinase activity | |
Biological Process | phosphorylation | |
Biological Process | polyphosphate biosynthetic process |
Keywords
- Molecular function
- Ligand
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended namePolyphosphate kinase
- EC number
- Alternative names
Gene names
Organism names
- Strain
- Taxonomic lineageBacteria > Spirochaetota > Spirochaetia > Leptospirales > Leptospiraceae > Leptospira
Accessions
- Primary accessionK8YBC6
Proteomes
Subcellular Location
UniProt Annotation
GO Annotation
PTM/Processing
Post-translational modification
An intermediate of this reaction is the autophosphorylated ppk in which a phosphate is covalently linked to a histidine residue through a N-P bond.
Keywords
- PTM
Interaction
Protein-protein interaction databases
Structure
Family & Domains
Features
Showing features for region, domain.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Region | 1-26 | Disordered | |||
Domain | 33-137 | Polyphosphate kinase N-terminal | |||
Domain | 150-329 | Polyphosphate kinase middle | |||
Domain | 358-523 | Polyphosphate kinase C-terminal | |||
Domain | 530-702 | Polyphosphate kinase C-terminal | |||
Sequence similarities
Belongs to the polyphosphate kinase 1 (PPK1) family.
Family and domain databases
Sequence
- Sequence statusComplete
- Length710
- Mass (Da)81,689
- Last updated2013-02-06 v1
- Checksum714195667B28B05D
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
CP006694 EMBL· GenBank· DDBJ | EKT87767.1 EMBL· GenBank· DDBJ | Genomic DNA |