K7ZSN9 · K7ZSN9_CANLF
- ProteinAmino acid transporter
- GeneSLC1A5
- StatusUniProtKB unreviewed (TrEMBL)
- Amino acids544 (go to sequence)
- Protein existenceEvidence at transcript level
- Annotation score4/5
Function
Catalytic activity
- D-serine(in) + L-alanine(out) + Na+(out) = D-serine(out) + L-alanine(in) + Na+(in)D-serine (in)CHEBI:35247
+ L-alanine (out)CHEBI:57972+ Na+ (out)CHEBI:29101= D-serine (out)CHEBI:35247+ L-alanine (in)CHEBI:57972+ Na+ (in)CHEBI:29101 - D-serine(in) + L-glutamine(out) + Na+(out) = D-serine(out) + L-glutamine(in) + Na+(in)
- H+(out) + L-glutamate(out) + L-glutamine(in) + Na+(out) = H+(in) + L-glutamate(in) + L-glutamine(out) + Na+(in)
- L-alanine(out) + L-glutamine(in) + Na+(out) = L-alanine(in) + L-glutamine(out) + Na+(in)
- L-asparagine(in) + L-glutamine(out) + Na+(out) = L-asparagine(out) + L-glutamine(in) + Na+(in)
- L-asparagine(out) + L-glutamine(in) + Na+(out) = L-asparagine(in) + L-glutamine(out) + Na+(in)
- L-glutamine(in) + L-methionine(out) + Na+(out) = L-glutamine(out) + L-methionine(in) + Na+(in)
- L-glutamine(in) + L-serine(out) + Na+(out) = L-glutamine(out) + L-serine(in) + Na+(in)
- L-glutamine(in) + L-threonine(out) + Na+(out) = L-glutamine(out) + L-threonine(in) + Na+(in)
- L-glutamine(in) + L-valine(out) + Na+(out) = L-glutamine(out) + L-valine(in) + Na+(in)
- L-glutamine(out) + L-serine(in) + Na+(out) = L-glutamine(in) + L-serine(out) + Na+(in)
- L-glutamine(out) + L-threonine(in) + Na+(out) = L-glutamine(in) + L-threonine(out) + Na+(in)
- iodide(out) = iodide(in)
- nitrate(in) = nitrate(out)
- thiocyanate(in) = thiocyanate(out)
GO annotations
Aspect | Term | |
---|---|---|
Cellular Component | melanosome | |
Cellular Component | plasma membrane | |
Molecular Function | antiporter activity | |
Molecular Function | metal ion binding | |
Molecular Function | symporter activity | |
Biological Process | L-alpha-amino acid transmembrane transport |
Keywords
- Biological process
- Ligand
Names & Taxonomy
Protein names
- Recommended nameAmino acid transporter
Gene names
Organism names
- Taxonomic lineageEukaryota > Metazoa > Chordata > Craniata > Vertebrata > Euteleostomi > Mammalia > Eutheria > Laurasiatheria > Carnivora > Caniformia > Canidae > Canis
Accessions
- Primary accessionK7ZSN9
Subcellular Location
UniProt Annotation
GO Annotation
Cell membrane ; Multi-pass membrane protein
Membrane ; Multi-pass membrane protein
Features
Showing features for transmembrane.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Transmembrane | 52-76 | Helical | ||||
Sequence: ANLLVLLTVVAVVAGVALGMGVSGA | ||||||
Transmembrane | 96-118 | Helical | ||||
Sequence: LLLRLLKMIILPLVVCSLIGGAA | ||||||
Transmembrane | 130-154 | Helical | ||||
Sequence: AWALLFFLVTTLLASALGVVLALAL | ||||||
Transmembrane | 229-246 | Helical | ||||
Sequence: SMNILGLVVFAIVLGVAL | ||||||
Transmembrane | 267-291 | Helical | ||||
Sequence: TMVLVSWIMWYAPVGILFLVAGKIV | ||||||
Transmembrane | 303-328 | Helical | ||||
Sequence: LGKYILCCLLGHAIHAIHGLLVLPLI | ||||||
Transmembrane | 340-361 | Helical | ||||
Sequence: FLWGIMTALATAFGTSSSSATL | ||||||
Transmembrane | 381-406 | Helical | ||||
Sequence: FILPIGATVNMDGAALFQCVAAVFIA | ||||||
Transmembrane | 418-447 | Helical | ||||
Sequence: IITILVTATASSVGAAGIPAGGVLTLAIIL |
Keywords
- Cellular component
PTM/Processing
Keywords
- PTM
Structure
Family & Domains
Features
Showing features for region.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Region | 1-28 | Disordered | ||||
Sequence: MVADPPRGDPKGLAAAEPTANGAPTLAP | ||||||
Region | 510-544 | Disordered | ||||
Sequence: PLSPLPVPTEEGNPLLKQCPRPAGDADPCEKESVM |
Sequence similarities
Keywords
- Domain
Phylogenomic databases
Family and domain databases
Sequence
- Sequence statusComplete
- Length544
- Mass (Da)57,180
- Last updated2013-02-06 v1
- Checksum95C1E3DE40B8A786
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
AB635686 EMBL· GenBank· DDBJ | BAM68257.1 EMBL· GenBank· DDBJ | mRNA |