K7W909 · K7W909_OCHER

Function

function

Monomeric heme protein which primary function is to store oxygen and facilitate its diffusion within muscle tissues. Reversibly binds oxygen through a pentacoordinated heme iron and enables its timely and efficient release as needed during periods of heightened demand. Depending on the oxidative conditions of tissues and cells, and in addition to its ability to bind oxygen, it also has a nitrite reductase activity whereby it regulates the production of bioactive nitric oxide. Under stress conditions, like hypoxia and anoxia, it also protects cells against reactive oxygen species thanks to its pseudoperoxidase activity.

Catalytic activity

GO annotations

AspectTerm
Cellular Componentextracellular exosome
Cellular Componentsarcoplasm
Molecular Functionheme binding
Molecular Functionmetal ion binding
Molecular Functionoxidoreductase activity
Molecular Functionoxygen binding
Molecular Functionoxygen carrier activity

Keywords

Names & Taxonomy

Protein names

  • Recommended name
    Myoglobin

Organism names

  • Taxonomic identifier
  • Taxonomic lineage
    Eukaryota > Metazoa > Chordata > Craniata > Vertebrata > Euteleostomi > Mammalia > Eutheria > Euarchontoglires > Glires > Lagomorpha > Ochotonidae > Ochotona

Accessions

  • Primary accession
    K7W909

Subcellular Location

Keywords

Family & Domains

Features

Showing features for domain.

TypeIDPosition(s)Description
Domain3-148Globin

Sequence similarities

Belongs to the globin family.

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    154
  • Mass (Da)
    17,082
  • Last updated
    2013-02-06 v1
  • Checksum
    2A6526853F801D77
MGLSDGEWQLVLTVWGKVEADLAGHGQEVLIRLFKNHPETLEKFDKFKNLKSEDEMKGSDDLKKHGNTVLSALGGILKKKGQHEAELKPLAQSHATKHKIPVKYLEFISEAIIQVLQSKHPGDFGADAQGAMSKALEVFRNDMAAKYKELGFQG

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
JX827175
EMBL· GenBank· DDBJ
AFX00022.1
EMBL· GenBank· DDBJ
mRNA

Similar Proteins

Disclaimer

Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care. Our staff consists of biologists and biochemists that are not trained to give medical advice.
We'd like to inform you that we have updated our Privacy Notice to comply with Europe’s new General Data Protection Regulation (GDPR) that applies since 25 May 2018.
Help