K7W633 · K7W633_9BASI
- ProteinSerine/threonine-protein phosphatase
- GeneCNA1
- StatusUniProtKB unreviewed (TrEMBL)
- Amino acids698 (go to sequence)
- Protein existenceEvidence at transcript level
- Annotation score3/5
Function
Catalytic activity
- H2O + O-phospho-L-seryl-[protein] = L-seryl-[protein] + phosphate
Cofactor
Protein has several cofactor binding sites:
GO annotations
Aspect | Term | |
---|---|---|
Molecular Function | calmodulin binding | |
Molecular Function | calmodulin-dependent protein phosphatase activity | |
Molecular Function | metal ion binding | |
Molecular Function | myosin phosphatase activity | |
Biological Process | calcineurin-mediated signaling |
Keywords
- Molecular function
- Ligand
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended nameSerine/threonine-protein phosphatase
- EC number
Gene names
Organism names
- Taxonomic lineageEukaryota > Fungi > Dikarya > Basidiomycota > Pucciniomycotina > Pucciniomycetes > Pucciniales > Pucciniaceae > Puccinia
Accessions
- Primary accessionK7W633
Interaction
Subunit
Composed of two components (A and B), the A component is the catalytic subunit and the B component confers calcium sensitivity.
Structure
Family & Domains
Features
Showing features for domain, region, compositional bias.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Domain | 191-196 | Serine/threonine specific protein phosphatases | ||||
Sequence: LRGNHE | ||||||
Region | 423-449 | Disordered | ||||
Sequence: EQEEELPLATEEIESDPDPPSAAASAE | ||||||
Region | 539-698 | Disordered | ||||
Sequence: EFAESRSPGAADAGEPNRSRSRSGTLNSLAGSNDGRLPFGDYASGTSSVPTSPALPGTPDRPTIGSASGTPAGEGLGFSPTTPGGSPKFKRGHARRGSLGTTMTSPSTRRRSLENTISMIKEAMEGQADPEMEDLADAVAQNASHARHHSRSSSGSGSAS | ||||||
Compositional bias | 556-570 | Polar residues | ||||
Sequence: RSRSRSGTLNSLAGS | ||||||
Compositional bias | 636-652 | Polar residues | ||||
Sequence: SLGTTMTSPSTRRRSLE | ||||||
Compositional bias | 683-698 | Polar residues | ||||
Sequence: HARHHSRSSSGSGSAS |
Sequence similarities
Belongs to the PPP phosphatase family. PP-2B subfamily.
Family and domain databases
Sequence
- Sequence statusComplete
- Length698
- Mass (Da)76,736
- Last updated2013-02-06 v1
- Checksum5D3791D45305AFF3
Features
Showing features for compositional bias.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Compositional bias | 556-570 | Polar residues | ||||
Sequence: RSRSRSGTLNSLAGS | ||||||
Compositional bias | 636-652 | Polar residues | ||||
Sequence: SLGTTMTSPSTRRRSLE | ||||||
Compositional bias | 683-698 | Polar residues | ||||
Sequence: HARHHSRSSSGSGSAS |