K7W633 · K7W633_9BASI

Function

Catalytic activity

Cofactor

Protein has several cofactor binding sites:
Fe3+ (UniProtKB | Rhea| CHEBI:29034 )

Zn2+ (UniProtKB | Rhea| CHEBI:29105 )

GO annotations

AspectTerm
Molecular Functioncalmodulin binding
Molecular Functioncalmodulin-dependent protein phosphatase activity
Molecular Functionmetal ion binding
Molecular Functionmyosin phosphatase activity
Biological Processcalcineurin-mediated signaling

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    Serine/threonine-protein phosphatase
  • EC number

Gene names

    • Name
      CNA1

Organism names

Accessions

  • Primary accession
    K7W633

Interaction

Subunit

Composed of two components (A and B), the A component is the catalytic subunit and the B component confers calcium sensitivity.

Family & Domains

Features

Showing features for domain, region, compositional bias.

TypeIDPosition(s)Description
Domain191-196Serine/threonine specific protein phosphatases
Region423-449Disordered
Region539-698Disordered
Compositional bias556-570Polar residues
Compositional bias636-652Polar residues
Compositional bias683-698Polar residues

Sequence similarities

Belongs to the PPP phosphatase family. PP-2B subfamily.

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    698
  • Mass (Da)
    76,736
  • Last updated
    2013-02-06 v1
  • Checksum
    5D3791D45305AFF3
MSTGLPESSESASTSSLAAKLKQQQAGLKSIRDRLTLPEIDFTLHTLDDGAVVSTQERVVKEVQAPAFLKPTDAEFFSTVDPSKPDVAFLKNHFYREGRLTEDQALFILNKASEVLKTEPNLLEVEAPITVCGDIHGQYFDLMKLFEVGGNPAETRYLFLGDYVDRGYFSIECVLYLWALKIWYPDTLFLLRGNHECRHLTDYFTFKLECKHKYSERVYDACMESFCSLPLAAVMNKQFLCIHGGLSPELQTLDDLKGVNRFREPPTHGLMCDILWADPLEDFGSEKAAEGFVHNHVRGCSFFFSYQAACAFLERNGLLSIIRAHEAQDAGYRMYKKTKTTGFPSVMTIFSAPNYLDVYNNKAAVLKYENNVMNIRQFNCTPHPYWLPNFMDVFTWSLPFVGEKITDMLIAILGICTKEELDEQEEELPLATEEIESDPDPPSAAASAERRQAIKNKIMAVGKMSRVFAVLREEAEAVSELKSTTVQAKLPYGALANGAEGTKENILKAGFDQARKSDIENEHLPPELIDAADVEGFEEFAESRSPGAADAGEPNRSRSRSGTLNSLAGSNDGRLPFGDYASGTSSVPTSPALPGTPDRPTIGSASGTPAGEGLGFSPTTPGGSPKFKRGHARRGSLGTTMTSPSTRRRSLENTISMIKEAMEGQADPEMEDLADAVAQNASHARHHSRSSSGSGSAS

Features

Showing features for compositional bias.

TypeIDPosition(s)Description
Compositional bias556-570Polar residues
Compositional bias636-652Polar residues
Compositional bias683-698Polar residues

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
JX424819
EMBL· GenBank· DDBJ
AFW98882.1
EMBL· GenBank· DDBJ
mRNA

Similar Proteins

Disclaimer

Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care. Our staff consists of biologists and biochemists that are not trained to give medical advice.
We'd like to inform you that we have updated our Privacy Notice to comply with Europe’s new General Data Protection Regulation (GDPR) that applies since 25 May 2018.
FeedbackHelp