K7GDT5 · K7GDT5_PELSI

Function

Caution

Lacks conserved residue(s) required for the propagation of feature annotation.

Catalytic activity

Features

Showing features for binding site, site.

145050100150200250300350400450
TypeIDPosition(s)Description
Binding site231-236strychnine (UniProtKB | ChEBI)
Site290Important for obstruction of the ion pore in the closed conformation

GO annotations

AspectTerm
Cellular Componentchloride channel complex
Cellular Componentdendrite
Cellular Componentexternal side of plasma membrane
Cellular Componentglycinergic synapse
Cellular Componentinhibitory synapse
Cellular Componentintracellular membrane-bounded organelle
Cellular Componentperikaryon
Cellular Componentpostsynaptic membrane
Molecular Functionextracellularly glycine-gated chloride channel activity
Molecular Functionglycine binding
Molecular Functionligand-gated monoatomic ion channel activity involved in regulation of presynaptic membrane potential
Molecular Functiontaurine binding
Molecular Functiontransmembrane signaling receptor activity
Molecular Functiontransmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential
Molecular Functionzinc ion binding
Biological Processacrosome reaction
Biological Processadult walking behavior
Biological Processcellular response to amino acid stimulus
Biological Processcellular response to ethanol
Biological Processcellular response to zinc ion
Biological Processinhibitory postsynaptic potential
Biological Processmuscle contraction
Biological Processnegative regulation of transmission of nerve impulse
Biological Processneuromuscular process controlling posture
Biological Processneuronal action potential
Biological Processneuropeptide signaling pathway
Biological Processpositive regulation of acrosome reaction
Biological Processregulation of respiratory gaseous exchange by nervous system process
Biological Processrighting reflex
Biological Processstartle response
Biological Processsynaptic transmission, glycinergic
Biological Processvisual perception

Keywords

Names & Taxonomy

Protein names

  • Submitted names
    • Glycine receptor alpha 1

Gene names

    • Name
      GLRA1

Organism names

Accessions

  • Primary accession
    K7GDT5

Proteomes

Subcellular Location

Cell projection, dendrite
Membrane
; Multi-pass membrane protein
Perikaryon
Postsynaptic cell membrane
; Multi-pass membrane protein
Synapse
Synaptic cell membrane
; Multi-pass membrane protein

Features

Showing features for transmembrane.

TypeIDPosition(s)Description
Transmembrane251-273Helical
Transmembrane314-337Helical
Transmembrane422-442Helical

Keywords

PTM/Processing

Features

Showing features for signal, chain, disulfide bond.

TypeIDPosition(s)Description
Signal1-28
ChainPRO_502224940429-450
Disulfide bond167↔181
Disulfide bond227↔238

Keywords

Interaction

Protein-protein interaction databases

Family & Domains

Features

Showing features for domain.

TypeIDPosition(s)Description
Domain44-249Neurotransmitter-gated ion-channel ligand-binding
Domain256-342Neurotransmitter-gated ion-channel transmembrane

Sequence similarities

Keywords

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    450
  • Mass (Da)
    51,659
  • Last updated
    2013-01-09 v1
  • Checksum
    8F9F80022DC4C70C
MCNVNAFGVYVWETLVFFSLAASKEAEAAARSAPKPMSPSDFLDKLMGRTSGYDARIRPNFKGPAVNVSCNIFINSFGSIAETTMDYRVNIFLRQQWNDPRLAYNEYPDDSLDLDPSMLDSIWKPDLFFANEKGAHFHEITTDNKLLRISRNGNVLYSIRITLTLACPMDLKNFPMDVQTCIMQLESFGYTMNDLIFEWQEKGAVQVADGLTLPQFILKEEKDLRYCTKHYNTGKFTCIEARFHLERQMGYYLIQMYIPSLLIVILSWISFWINMDAAPARVGLGITTVLTMTTQSSGSRASLPKVSYVKAIDIWMAVCLLFVFSALLEYAAVNFVSRQHKELLRFRRRRRHHKEDEAGEGRFNFSAYGMGPACLQAKDGLSVKGANNNNTANPVPVQCRSPDEMRKLFIQRAKKIDKISHICFPMAFLIFNIFYWIIYKIVRREDVHNK

Keywords

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
AGCU01196895
EMBL· GenBank· DDBJ
-Genomic DNA No translation available.
AGCU01196896
EMBL· GenBank· DDBJ
-Genomic DNA No translation available.
AGCU01196897
EMBL· GenBank· DDBJ
-Genomic DNA No translation available.
AGCU01196898
EMBL· GenBank· DDBJ
-Genomic DNA No translation available.
AGCU01196899
EMBL· GenBank· DDBJ
-Genomic DNA No translation available.
AGCU01196900
EMBL· GenBank· DDBJ
-Genomic DNA No translation available.

Genome annotation databases

Similar Proteins

Disclaimer

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