K7G8X2 · K7G8X2_PELSI
- ProteinCalcium-transporting ATPase
- GeneATP2C2
- StatusUniProtKB unreviewed (TrEMBL)
- Amino acids940 (go to sequence)
- Protein existenceInferred from homology
- Annotation score4/5
Function
function
Catalyzes the hydrolysis of ATP coupled with the transport of calcium.
Catalytic activity
- Ca2+(in) + ATP + H2O = Ca2+(out) + ADP + phosphate + H+Ca2+ (in)CHEBI:29108
+ CHEBI:30616 + CHEBI:15377 = Ca2+ (out)CHEBI:29108+ CHEBI:456216 + CHEBI:43474 + CHEBI:15378 - Mn2+(in) + ATP + H2O = Mn2+(out) + ADP + phosphate + H+This reaction proceeds in the forward direction.
GO annotations
Aspect | Term | |
---|---|---|
Cellular Component | cytoplasmic side of plasma membrane | |
Cellular Component | cytoplasmic vesicle | |
Cellular Component | endoplasmic reticulum | |
Cellular Component | Golgi membrane | |
Cellular Component | perinuclear region of cytoplasm | |
Cellular Component | trans-Golgi network membrane | |
Molecular Function | ATP binding | |
Molecular Function | ATP hydrolysis activity | |
Molecular Function | P-type calcium transporter activity | |
Molecular Function | P-type manganese transporter activity | |
Biological Process | intracellular calcium ion homeostasis | |
Biological Process | mammary gland epithelium development | |
Biological Process | positive regulation of calcium ion import | |
Biological Process | protein localization to plasma membrane |
Keywords
- Molecular function
- Biological process
- Ligand
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended nameCalcium-transporting ATPase
- EC number
Gene names
Organism names
- Strain
- Taxonomic lineageEukaryota > Metazoa > Chordata > Craniata > Vertebrata > Euteleostomi > Archelosauria > Testudinata > Testudines > Cryptodira > Trionychia > Trionychidae > Pelodiscus
Accessions
- Primary accessionK7G8X2
Proteomes
Subcellular Location
UniProt Annotation
GO Annotation
Golgi apparatus, trans-Golgi network membrane ; Multi-pass membrane protein
Membrane ; Multi-pass membrane protein
Features
Showing features for transmembrane.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Transmembrane | 264-283 | Helical | |||
Transmembrane | 289-318 | Helical | |||
Transmembrane | 801-821 | Helical | |||
Transmembrane | 833-850 | Helical | |||
Transmembrane | 870-887 | Helical | |||
Transmembrane | 899-917 | Helical | |||
Keywords
- Cellular component
Interaction
Protein-protein interaction databases
Structure
Family & Domains
Features
Showing features for domain.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Domain | 20-96 | Cation-transporting P-type ATPase N-terminal | |||
Sequence similarities
Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IIA subfamily.
Keywords
- Domain
Phylogenomic databases
Family and domain databases
Sequence
- Sequence statusComplete
- Length940
- Mass (Da)102,670
- Last updated2013-01-09 v1
- Checksum59D890BB669A7F19
Keywords
- Technical term
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
AGCU01165103 EMBL· GenBank· DDBJ | - | Genomic DNA | No translation available. | |
AGCU01165104 EMBL· GenBank· DDBJ | - | Genomic DNA | No translation available. |