K7G779 · K7G779_PELSI

Function

function

Destroys radicals which are normally produced within the cells and which are toxic to biological systems.

Catalytic activity

Cofactor

Protein has several cofactor binding sites:
Cu cation (UniProtKB | Rhea| CHEBI:23378 )

Note: Binds 1 copper ion per subunit.
Zn2+ (UniProtKB | Rhea| CHEBI:29105 )

Note: Binds 1 zinc ion per subunit.

GO annotations

AspectTerm
Cellular Componentaxon cytoplasm
Cellular Componentcytoplasmic vesicle
Cellular Componentcytosol
Cellular Componentdendrite cytoplasm
Cellular Componentextracellular space
Cellular Componentmitochondrion
Cellular Componentneuronal cell body
Cellular Componentnucleoplasm
Cellular Componentperoxisome
Cellular Componentplasma membrane
Cellular Componentprotein-containing complex
Molecular Functioncopper ion binding
Molecular Functionprotein homodimerization activity
Molecular Functionprotein phosphatase 2B binding
Molecular Functionprotein-folding chaperone binding
Molecular Functionsmall GTPase binding
Molecular Functionsuperoxide dismutase activity
Molecular Functionzinc ion binding
Biological Processaction potential initiation
Biological Processanterograde axonal transport
Biological Processapoptotic process
Biological Processauditory receptor cell stereocilium organization
Biological Processdetermination of adult lifespan
Biological Processectopic germ cell programmed cell death
Biological Processembryo implantation
Biological Processgene expression
Biological Processglutathione metabolic process
Biological Processheart contraction
Biological Processhydrogen peroxide biosynthetic process
Biological Processintracellular iron ion homeostasis
Biological Processlocomotory behavior
Biological Processmuscle cell cellular homeostasis
Biological Processmyeloid cell homeostasis
Biological Processnegative regulation of developmental process
Biological Processnegative regulation of inflammatory response
Biological Processnegative regulation of neuron apoptotic process
Biological Processnegative regulation of reproductive process
Biological Processneurofilament cytoskeleton organization
Biological Processneuronal action potential
Biological Processovarian follicle development
Biological Processperipheral nervous system myelin maintenance
Biological Processpositive regulation of cytokine production
Biological Processpositive regulation of MAPK cascade
Biological Processpositive regulation of oxidative stress-induced intrinsic apoptotic signaling pathway
Biological Processpositive regulation of phagocytosis
Biological Processpositive regulation of superoxide anion generation
Biological Processregulation of blood pressure
Biological Processregulation of mitochondrial membrane potential
Biological Processregulation of multicellular organism growth
Biological Processrelaxation of vascular associated smooth muscle
Biological Processresponse to axon injury
Biological Processresponse to ethanol
Biological Processresponse to heat
Biological Processresponse to hydrogen peroxide
Biological Processresponse to xenobiotic stimulus
Biological Processretina homeostasis
Biological Processretrograde axonal transport
Biological Processsensory perception of sound
Biological Processspermatogenesis
Biological Processsuperoxide anion generation

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    Superoxide dismutase [Cu-Zn]
  • EC number

Gene names

    • Name
      SOD1

Organism names

Accessions

  • Primary accession
    K7G779

Proteomes

PTM/Processing

Keywords

Interaction

Protein-protein interaction databases

Family & Domains

Features

Showing features for domain.

TypeIDPosition(s)Description
Domain17-150Superoxide dismutase copper/zinc binding

Sequence similarities

Belongs to the Cu-Zn superoxide dismutase family.

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    155
  • Mass (Da)
    15,778
  • Last updated
    2013-01-09 v1
  • Checksum
    B5E3745E9DDB7475
MAAVKAVCVLQGEGAGKGVINFEQQGTGPVSLSGTIEGLTEGKHGFHVHEFGDNTNGCTSAGAHFNPHGKKHGGPQDQERHVGDLGNVTANKDGVAKVSITDSLISLNGPQSIIGRTMVVHEKDDDLGKGGNEESSKTGNAGARLACGVIGIAKI

Keywords

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
AGCU01106354
EMBL· GenBank· DDBJ
-Genomic DNA No translation available.
AGCU01106355
EMBL· GenBank· DDBJ
-Genomic DNA No translation available.
AGCU01106356
EMBL· GenBank· DDBJ
-Genomic DNA No translation available.
AGCU01106357
EMBL· GenBank· DDBJ
-Genomic DNA No translation available.

Genome annotation databases

Similar Proteins

Disclaimer

Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care. Our staff consists of biologists and biochemists that are not trained to give medical advice.
We'd like to inform you that we have updated our Privacy Notice to comply with Europe’s new General Data Protection Regulation (GDPR) that applies since 25 May 2018.
FeedbackHelp