K7G3M1 · K7G3M1_PELSI

Function

function

Receptor that may have an important role in cell/cell signaling during nervous system formation.

Caution

Lacks conserved residue(s) required for the propagation of feature annotation.

GO annotations

all annotationsall molecular functionvirus receptor activitydna bindingrna bindingcytoskeletal motor activitycatalytic activitygtpase activitystructural molecule activitytransporter activitycytoskeletal protein bindinglipid bindingcyclase activityantioxidant activityoxidoreductase activitytransferase activityhydrolase activitylyase activityisomerase activityligase activityprotein tag activitycargo receptor activityhistone bindingprotein folding chaperonetranslation regulator activitynutrient reservoir activityreceptor ligand activitymolecular transducer activitymolecular adaptor activitytoxin activitycell adhesion mediator activitymolecular function regulator activityvirus coreceptor activitycatalytic activity, acting on a proteincatalytic activity, acting on dnacatalytic activity, acting on rnamolecular carrier activitytranscription regulator activitygeneral transcription initiation factor activitymolecular sensor activitymolecular sequestering activityatp-dependent activityother molecular functionall biological processmitotic cell cyclecytokinesiscytoplasmic translationimmune system processmuscle system processcirculatory system processrenal system processrespiratory system processcarbohydrate metabolic processgeneration of precursor metabolites and energydna replicationdna repairdna recombinationchromatin organizationdna-templated transcriptionregulation of dna-templated transcriptiontrna metabolic processprotein foldingprotein glycosylationamino acid metabolic processmodified amino acid metabolic processlipid metabolic processvitamin metabolic processsulfur compound metabolic processintracellular protein transportnucleocytoplasmic transportautophagyinflammatory responsemitochondrion organizationcytoskeleton organizationmicrotubule-based movementperoxisome organizationlysosome organizationchromosome segregationcell adhesionestablishment or maintenance of cell polarityprogrammed cell deathphotosynthesismrna metabolic processsnrna metabolic processvesicle-mediated transportreproductive processdigestive system processsignalingcell differentiationprotein catabolic processextracellular matrix organizationregulatory ncrna-mediated gene silencingtelomere organizationcell junction organizationwound healingribosome biogenesiscilium organizationanatomical structure developmentcell motilitynervous system processendocrine processprotein maturationtransmembrane transportnucleobase-containing small molecule metabolic processhepaticobiliary system processmembrane organizationprotein-containing complex assemblycell wall organization or biogenesisnitrogen cycle metabolic processprotein localization to plasma membranedefense response to other organismdetoxificationmeiotic nuclear divisionmitotic nuclear divisionmitochondrial gene expressioncarbohydrate derivative metabolic processother biological processall cellular componentnuclear chromosomeextracellular regionextracellular spacecell wallnucleusnuclear envelopenucleoplasmchromosomenucleolusmitochondrionlysosomeendosomevacuoleperoxisomeendoplasmic reticulumgolgi apparatuslipid dropletmicrotubule organizing centercytosolribosomecytoskeletonplasma membraneciliumplastidthylakoidexternal encapsulating structureextracellular matrixcytoplasmic vesicleorganelleother cellular component
Cell color indicative of number of GO terms
AspectTerm
Cellular Componentnucleoplasm
Cellular Componentplasma membrane
Molecular Functioncalcium ion binding
Molecular FunctionG protein-coupled receptor activity
Biological Processanterior/posterior pattern specification
Biological Processapical protein localization
Biological Processestablishment of body hair planar orientation
Biological Processestablishment of planar polarity of embryonic epithelium
Biological Processhair follicle development
Biological Processhomophilic cell adhesion via plasma membrane adhesion molecules
Biological Processinner ear morphogenesis
Biological Processlateral sprouting involved in lung morphogenesis
Biological Processlocomotory behavior
Biological Processmotor neuron migration
Biological Processorthogonal dichotomous subdivision of terminal units involved in lung branching morphogenesis
Biological Processplanar cell polarity pathway involved in neural tube closure
Biological Processplanar dichotomous subdivision of terminal units involved in lung branching morphogenesis
Biological Processprotein localization involved in establishment of planar polarity
Biological Processregulation of actin cytoskeleton organization
Biological ProcessRho protein signal transduction
Biological Processwound healing

Keywords

Names & Taxonomy

Protein names

  • Submitted names
    • Cadherin EGF LAG seven-pass G-type receptor 1

Gene names

    • Name
      CELSR1

Organism names

Accessions

  • Primary accession
    K7G3M1

Proteomes

Subcellular Location

Cell membrane
; Multi-pass membrane protein

Features

Showing features for transmembrane.

TypeIDPosition(s)Description
Transmembrane2182-2205Helical
Transmembrane2217-2235Helical
Transmembrane2241-2263Helical
Transmembrane2284-2304Helical
Transmembrane2324-2345Helical
Transmembrane2365-2387Helical
Transmembrane2393-2416Helical

Keywords

PTM/Processing

Features

Showing features for disulfide bond.

TypeIDPosition(s)Description
Disulfide bond1064↔1073
Disulfide bond1102↔1111
Disulfide bond1388↔1397
Disulfide bond1611↔1620
Disulfide bond1649↔1658
Disulfide bond1716↔1728
Disulfide bond1718↔1735
Disulfide bond1737↔1746

Keywords

Family & Domains

Features

Showing features for domain, compositional bias, region.

TypeIDPosition(s)Description
Domain9-71Cadherin
Domain72-179Cadherin
Domain180-285Cadherin
Domain286-401Cadherin
Domain402-503Cadherin
Domain504-606Cadherin
Domain607-712Cadherin
Domain713-814Cadherin
Domain837-937Cadherin
Domain1016-1074EGF-like
Domain1076-1112EGF-like
Domain1116-1154EGF-like
Domain1155-1359Laminin G
Domain1362-1398EGF-like
Domain1402-1583Laminin G
Domain1585-1621EGF-like
Domain1622-1659EGF-like
Domain1716-1763Laminin EGF-like
Domain1748-1821G-protein coupled receptors family 2 profile 1
Domain2180-2417G-protein coupled receptors family 2 profile 2
Compositional bias2482-2510Polar residues
Region2482-2547Disordered
Compositional bias2511-2525Basic and acidic residues
Region2584-2665Disordered
Compositional bias2594-2618Basic and acidic residues
Compositional bias2633-2649Polar residues

Sequence similarities

Belongs to the G-protein coupled receptor 2 family. LN-TM7 subfamily.

Keywords

Phylogenomic databases

Family and domain databases

Protein family/group databases

Sequence

  • Sequence status
    Complete
  • Length
    2,740
  • Mass (Da)
    304,261
  • Last updated
    2013-01-09 v1
  • Checksum
    F67CF48312F13C80
MEALFDERSNDYFSIDSETGSMVTTRSLDRETKDTHVLKVTATDHGSPRRRSATTYLTVTVSDTNDHEPMFEQPVYRETIRENLEVGYEVLTIRATDGDAPDNANMLYRLLEPGAGDGVFEIDPRSGVVRTRAPVDREEVSEYHLVVEANDQGKEPGPRSATATVHITVEDENDNYPQFSEKRYLVQVPEDAPVNSQVLQVQATDRDRGSNAQVHYSIVSGNLKGQFYIHSFSGAIDLINPLDYETIREYTLRIKAQDGGRPPLINSSGMVSVQVVDVNDNAPIFVSTPFQATVLENVPLGYSVLHVQAVDADSGDNARLEYKLIDLSPSPGGVSPGGDTGFPFQINNSTGWITVSAELDRETVENYHFGVEARDHGVPVMTSSASVAITVLDVNDNNPSFTEKVYQLRLNEDAAVGSSVLTVIAVDRDINSVVTYQITSGNTRNRFAITSQSGGGLITLALPLDYKQERQYVLTVTASDGTLLDTVQVFINVTDANTHRPVFQSSHYTVSVSEDKPIGTSIVTISASDEDTGENARITYILEDNIPQFRIDPDTGTITTLMELDYEDQASYTLAITARDNGIPQKSDTTYVEILILDANDNAPRFLRDRYQGSVFEDVPLSTSVLQLSATDRDSGLNGRLLYTFQGGDDGDGDFYIEPTSGVIRTLRKLDRENVAVYSLRAFAVDRGSPPLKASVDIQVTVLDINDNPPVFEQDEFDIFVEENSPVGSIVARISAADPDEGTNAQIMYQIVEGNIPEVFQLDLLNGDLTALMDLDYESRTEYVIVVQATSAPLVSRATVHIRLLDQNDNPPVLQDFQILFNNYVTNKSNSFPSGVIGKIPAHDPDVSDSLAYAFVQGNELNLLLLDSATGELKLSRDLDNNRPLEALMKVSVSDGVHSVTAVCTLRVTIITDDMLTNSITVRLENMSQEKFLSPLLSLFVEGVATVLSTTTDGIFVFNIQNDTDVSSNILNVTFSALLPGGIRNKFFPSEDLQEQIYLNRTLLTMISMQRVLPFDDNICLREPCENYMKCVSVLKFDSSAPFISSNTVLFRPIHPINGLRCRCPPGFTGDYCETEIDLCYSNPCGNNGLCRSREGGYTCECYEDYTGESCEVNSRSGRCVPGVCKNGGTCVNLLVGGFKCECPPGEYERPYCEMTTRSFPPQSFVTFKGLRQRFHFTVSLMFATRERNALLLYNGRFNEKHDFIALEIIEEQIQLTFSAGETTTTVAPFVPGGVSDGQWHSVQVQYYNKPHIGRLGIPHGPSGEKVAVVTVDDCDTAVAVRFGSLIGNYTCAAQGTQTGSKKSLDLTGPLLLGGVPNLPEDFPVHNREFIGCMRNLSIDNKPIDMASFIANNGTLAGCAAQKNYCDTNWCQNGGTCVNKWNTYTCECPLQYGGKNCEQVMPSPQRFSGESIIVWSDLDITISVPWYIGLMFRTRKVNGMLMQANAGASSKINIQILNNYVQFEVYNGLNQVASLKMTQTRVSDGEWHHLLIELKSAKDGKDIKYLAVMSLDYGMYQSTVQIGNQLPGLKMKSIIVGGISGDQVSVQQGFYGCMQGVRMGETSTNVATLNMKQAIKINIKEGCEIDNPCDSSPCPQHSYCTDDWDSYSCVCDPGYFGSNCVDVCNLNPCEHVSTCVHKPSSSHGYTCECGQSYYGQYCESKIDLPCPRGWWGNPICGPCNCEISKGFDPDCNKTNGECQCKTNYYRPQSSDACYPCDCFPSGSQTRSCDLETGQCPCKPGVIGRQCNRCDNPFAEVTIQGCEVIYNGCPKAFEAGIWWPQTKFGQPAAVPCPKGSVGNAVRHCNSERGWLPPELFNCTTLIFVDLKLMIEKLHLNETKLDGDKSIQIAKVLQNATKYTNSLYGNDVRTAYLLMIKVLQYESQQQGFDLAATRDAEFNENIIKVGSTLLDPSTKEHWEQIQRTEGGTSHLLKHYEEYFNTVAQNMKKTYLKPFVIVATNMIIAVDIFDKSNFTGAKVPQFDRIKEDYPKDLESSVLFPDTLFRPSDRKVAPTMKPSNQKLSSKTDNGILNLENALTKRKKRQPDESNQYAVAMVIIYRSLGQLLPENYDPDRRSLRLPNRPIINTPIVSTTIYSQAEPVPNLLEKPIILEYAMLETEERTKPVCVFWNHSITVGGTGGWSSKGCELFSRNQSHVSCQCNHMTSFAVLMDISKRENGEVLPLKIVTYTTVSISLVALLMTFMLLVLIRTLRSNLHSIHRNLVAALFFSELVFLIGINQTENQFVCTVIAILLHYFYMSTFAWMFVEQLHIYRMLTEVRNINFGHMRFYYVVGWGIPAIITGLAVGLDPHGYGNPDFCWLSVHDTLIWSFAGPVVIVVIINTVIFILAVKASCGRRQRSFEKTGVMSVLRTAFLLLLLISATWLLGLMAVNSDVMTFHYLFAIFSCLQGLFIFFFHCIFNKEVRKHLKNTLTGKKPLPDDSTTTRATLLTRSLNCNNTYIEEPNMYRTNIGESTVSLESTIRDEAAQKLSGSSSQARTGQTEADSSIFHRNPSKSNENDSDSDSELSLDEHSSSYASSHSSESEEDGIEMEKKWNTATAKNNECGPIHSTPKVDSLPNHVKPYWPTECVTTSDGEDPGGKQKLKVETKVSVELHRENQVNHSNEAPQDNENEGQQKENKPVQQQNNQLPEQRKGILKNKVTYPPPLLDKNMKNRLREKLSDYNQTTISSRTAFLGNSDGIRSPSDTGVIIKTPRKEQNRDQLNGMAMNVHVGTVTAETSDSEQ

Features

Showing features for compositional bias.

TypeIDPosition(s)Description
Compositional bias2482-2510Polar residues
Compositional bias2511-2525Basic and acidic residues
Compositional bias2594-2618Basic and acidic residues
Compositional bias2633-2649Polar residues

Keywords

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
AGCU01067599
EMBL· GenBank· DDBJ
-Genomic DNA No translation available.
AGCU01067600
EMBL· GenBank· DDBJ
-Genomic DNA No translation available.
AGCU01067601
EMBL· GenBank· DDBJ
-Genomic DNA No translation available.
AGCU01067602
EMBL· GenBank· DDBJ
-Genomic DNA No translation available.
AGCU01067603
EMBL· GenBank· DDBJ
-Genomic DNA No translation available.
AGCU01067604
EMBL· GenBank· DDBJ
-Genomic DNA No translation available.
AGCU01067605
EMBL· GenBank· DDBJ
-Genomic DNA No translation available.
AGCU01067606
EMBL· GenBank· DDBJ
-Genomic DNA No translation available.
AGCU01067607
EMBL· GenBank· DDBJ
-Genomic DNA No translation available.
AGCU01067608
EMBL· GenBank· DDBJ
-Genomic DNA No translation available.

Genome annotation databases

Similar Proteins

Disclaimer

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