K7FYT0 · K7FYT0_PELSI

Function

function

Calcium-regulated non-lysosomal thiol-protease.

Catalytic activity

Features

Showing features for active site.

1810100200300400500600700800
TypeIDPosition(s)Description
Active site123
Active site327
Active site351

GO annotations

all annotationsall molecular functionvirus receptor activitydna bindingrna bindingcytoskeletal motor activitycatalytic activitygtpase activitystructural molecule activitytransporter activitycytoskeletal protein bindinglipid bindingcyclase activityantioxidant activityoxidoreductase activitytransferase activityhydrolase activitylyase activityisomerase activityligase activityprotein tag activitycargo receptor activityhistone bindingprotein folding chaperonetranslation regulator activitynutrient reservoir activityreceptor ligand activitymolecular transducer activitymolecular adaptor activitytoxin activitycell adhesion mediator activitymolecular function regulator activityvirus coreceptor activitycatalytic activity, acting on a proteincatalytic activity, acting on dnacatalytic activity, acting on rnamolecular carrier activitytranscription regulator activitygeneral transcription initiation factor activitymolecular sensor activitymolecular sequestering activityatp-dependent activityother molecular functionall biological processmitotic cell cyclecytokinesiscytoplasmic translationimmune system processmuscle system processcirculatory system processrenal system processrespiratory system processcarbohydrate metabolic processgeneration of precursor metabolites and energydna replicationdna repairdna recombinationchromatin organizationdna-templated transcriptionregulation of dna-templated transcriptiontrna metabolic processprotein foldingprotein glycosylationamino acid metabolic processmodified amino acid metabolic processlipid metabolic processvitamin metabolic processsulfur compound metabolic processintracellular protein transportnucleocytoplasmic transportautophagyinflammatory responsemitochondrion organizationcytoskeleton organizationmicrotubule-based movementperoxisome organizationlysosome organizationchromosome segregationcell adhesionestablishment or maintenance of cell polarityprogrammed cell deathphotosynthesismrna metabolic processsnrna metabolic processvesicle-mediated transportreproductive processdigestive system processsignalingcell differentiationprotein catabolic processextracellular matrix organizationregulatory ncrna-mediated gene silencingtelomere organizationcell junction organizationwound healingribosome biogenesiscilium organizationanatomical structure developmentcell motilitynervous system processendocrine processprotein maturationtransmembrane transportnucleobase-containing small molecule metabolic processhepaticobiliary system processmembrane organizationprotein-containing complex assemblycell wall organization or biogenesisnitrogen cycle metabolic processprotein localization to plasma membranedefense response to other organismdetoxificationmeiotic nuclear divisionmitotic nuclear divisionmitochondrial gene expressioncarbohydrate derivative metabolic processother biological processall cellular componentnuclear chromosomeextracellular regionextracellular spacecell wallnucleusnuclear envelopenucleoplasmchromosomenucleolusmitochondrionlysosomeendosomevacuoleperoxisomeendoplasmic reticulumgolgi apparatuslipid dropletmicrotubule organizing centercytosolribosomecytoskeletonplasma membraneciliumplastidthylakoidexternal encapsulating structureextracellular matrixcytoplasmic vesicleorganelleother cellular component
Cell color indicative of number of GO terms
AspectTerm
Cellular Componentcytosol
Cellular Componentnucleolus
Cellular Componentplasma membrane
Cellular Componentprotein-containing complex
Molecular Functioncalcium ion binding
Molecular Functioncalcium-dependent cysteine-type endopeptidase activity
Molecular Functionligase regulator activity
Molecular Functionmolecular adaptor activity
Molecular Functionsodium ion binding
Molecular Functionstructural constituent of muscle
Molecular Functiontitin binding
Biological Processcalcium-dependent self proteolysis
Biological Processcellular response to calcium ion
Biological Processcellular response to salt stress
Biological ProcessG1 to G0 transition involved in cell differentiation
Biological Processnegative regulation of apoptotic process
Biological Processnegative regulation of DNA-templated transcription
Biological Processnegative regulation of protein sumoylation
Biological Processpositive regulation of DNA-templated transcription
Biological Processpositive regulation of proteolysis
Biological Processpositive regulation of release of sequestered calcium ion into cytosol
Biological Processpositive regulation of satellite cell activation involved in skeletal muscle regeneration
Biological Processprogrammed cell death
Biological Processprotein catabolic process
Biological Processprotein destabilization
Biological Processprotein localization to membrane
Biological Processprotein-containing complex assembly
Biological Processregulation of canonical NF-kappaB signal transduction
Biological Processregulation of myoblast differentiation
Biological Processsarcomere organization

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    Calpain-3
  • EC number

Gene names

    • Name
      CAPN3

Organism names

Accessions

  • Primary accession
    K7FYT0

Proteomes

Subcellular Location

Keywords

Interaction

Subunit

Homodimer.

Protein-protein interaction databases

Family & Domains

Features

Showing features for domain, region.

TypeIDPosition(s)Description
Domain68-410Calpain catalytic
Region608-641Disordered
Domain681-707EF-hand
Domain711-746EF-hand
Domain776-810EF-hand

Sequence similarities

Belongs to the peptidase C2 family.

Keywords

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    810
  • Mass (Da)
    93,405
  • Last updated
    2013-01-09 v1
  • Checksum
    B0A3448516226FDD
MPSAINAVVAQQTEAGSVPSTNISTTAETGGGPGGIYSAIISRNQPIIRVKEKTFEELHKKCLEKKILYEDPDFPPNESSLFYNQKLPVKFEWKRPPEICENPRFIIGGANRTDICQGELGDCWFLAAIACLTLNEKLLCRVIPHDQTFIKNYAGIFHFQFWRYGDWVDVVVDDFLPTYNNQLVFTKSSQRNEFWSALLEKAYAKLHGSYEALKGGNTTEAMEDFTGGVTEFYEIKDAPKDIYKIMKHASDRGSLMACSIDDNMGFSYGSAPQSDLGELIARMVKNVNSMPQIDPALEFQSVDERPAWTIVPMQFETRMTCGLVKGHAYSVTAVEETSFKAGKIKLVRLRNPWGQVEWKGAWSDRSDEWTLIDKAEKIRLQHNIEEDGEFWMSFEDFMRYFTKLEICNITPDTLEADKLHTWTVSVNEGRWVRGCSGGGCRNYPDTFWTNPQYRLKLLEEDDDPEDNEVVCSFLVALMQKNRRKERKLGANLLTIGFAIYEVPKEMHGNKQHLQKDFFLYNASKARSKSYINIREVSERFRLPPSEYVIIPSTYEPHQEGEFILRVFSEKRNLSEEVENKIEVERPSKKKKDKPIIFVSDRANSNKELKVDDISDKEKKKTSRDEKKPTPTKSDKDSEEEEQFRNIFQQIAGDDMEISADELRSVLNNVLKKHKDLKTEGFALESCRSMIALMDTDGSGKINFQEFQHLWNKLKSWQKIFKHYDTDHSGTINSYEMRNAVKDAGFSLNKQLYDIITMRYADKNMNIEFDSFICCFVRLEGMFRAFHAFDKDGDGIIKLNVLEWLQLTMYA

Computationally mapped potential isoform sequences

There is 1 potential isoform mapped to this entry

View all
EntryEntry nameGene nameLength
K7FYC7K7FYC7_PELSICAPN3705

Keywords

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
AGCU01135040
EMBL· GenBank· DDBJ
-Genomic DNA No translation available.
AGCU01135041
EMBL· GenBank· DDBJ
-Genomic DNA No translation available.
AGCU01135042
EMBL· GenBank· DDBJ
-Genomic DNA No translation available.

Genome annotation databases

Similar Proteins

Disclaimer

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