K7FBC9 · K7FBC9_PELSI

Function

Features

Showing features for binding site, active site.

1956100200300400500600700800900
TypeIDPosition(s)Description
Binding site597-605ATP (UniProtKB | ChEBI)
Binding site623ATP (UniProtKB | ChEBI)
Active site716Proton acceptor

GO annotations

all annotationsall molecular functionvirus receptor activitydna bindingrna bindingcytoskeletal motor activitycatalytic activitygtpase activitystructural molecule activitytransporter activitycytoskeletal protein bindinglipid bindingcyclase activityantioxidant activityoxidoreductase activitytransferase activityhydrolase activitylyase activityisomerase activityligase activityprotein tag activitycargo receptor activityhistone bindingprotein folding chaperonetranslation regulator activitynutrient reservoir activityreceptor ligand activitymolecular transducer activitymolecular adaptor activitytoxin activitycell adhesion mediator activitymolecular function regulator activityvirus coreceptor activitycatalytic activity, acting on a proteincatalytic activity, acting on dnacatalytic activity, acting on rnamolecular carrier activitytranscription regulator activitygeneral transcription initiation factor activitymolecular sensor activitymolecular sequestering activityatp-dependent activityother molecular functionall biological processmitotic cell cyclecytokinesiscytoplasmic translationimmune system processmuscle system processcirculatory system processrenal system processrespiratory system processcarbohydrate metabolic processgeneration of precursor metabolites and energydna replicationdna repairdna recombinationchromatin organizationdna-templated transcriptionregulation of dna-templated transcriptiontrna metabolic processprotein foldingprotein glycosylationamino acid metabolic processmodified amino acid metabolic processlipid metabolic processvitamin metabolic processsulfur compound metabolic processintracellular protein transportnucleocytoplasmic transportautophagyinflammatory responsemitochondrion organizationcytoskeleton organizationmicrotubule-based movementperoxisome organizationlysosome organizationchromosome segregationcell adhesionestablishment or maintenance of cell polarityprogrammed cell deathphotosynthesismrna metabolic processsnrna metabolic processvesicle-mediated transportreproductive processdigestive system processsignalingcell differentiationprotein catabolic processextracellular matrix organizationregulatory ncrna-mediated gene silencingtelomere organizationcell junction organizationwound healingribosome biogenesiscilium organizationanatomical structure developmentcell motilitynervous system processendocrine processprotein maturationtransmembrane transportnucleobase-containing small molecule metabolic processhepaticobiliary system processmembrane organizationprotein-containing complex assemblycell wall organization or biogenesisnitrogen cycle metabolic processprotein localization to plasma membranedefense response to other organismdetoxificationmeiotic nuclear divisionmitotic nuclear divisionmitochondrial gene expressioncarbohydrate derivative metabolic processother biological processall cellular componentnuclear chromosomeextracellular regionextracellular spacecell wallnucleusnuclear envelopenucleoplasmchromosomenucleolusmitochondrionlysosomeendosomevacuoleperoxisomeendoplasmic reticulumgolgi apparatuslipid dropletmicrotubule organizing centercytosolribosomecytoskeletonplasma membraneciliumplastidthylakoidexternal encapsulating structureextracellular matrixcytoplasmic vesicleorganelleother cellular component
Cell color indicative of number of GO terms
AspectTerm
Cellular Componentaxon
Cellular Componentdendrite
Cellular Componentearly endosome membrane
Cellular Componentglutamatergic synapse
Cellular Componentpostsynaptic membrane
Cellular Componentpresynaptic membrane
Cellular ComponentSchaffer collateral - CA1 synapse
Molecular FunctionATP binding
Molecular FunctionDH domain binding
Molecular FunctionGPI-linked ephrin receptor activity
Molecular Functionidentical protein binding
Molecular FunctionPH domain binding
Molecular Functionprotein tyrosine kinase binding
Molecular Functiontransmembrane-ephrin receptor activity
Biological Processadherens junction organization
Biological Processadult walking behavior
Biological Processcellular response to amyloid-beta
Biological Processcochlea development
Biological Processcorticospinal tract morphogenesis
Biological Processfasciculation of motor neuron axon
Biological Processfasciculation of sensory neuron axon
Biological Processmotor neuron axon guidance
Biological Processnegative regulation of axon regeneration
Biological Processnegative regulation of cell adhesion
Biological Processnegative regulation of cell migration
Biological Processnegative regulation of cellular response to hypoxia
Biological Processnegative regulation of epithelial to mesenchymal transition
Biological Processnegative regulation of ERK1 and ERK2 cascade
Biological Processnegative regulation of long-term synaptic potentiation
Biological Processnegative regulation of proteolysis involved in protein catabolic process
Biological Processnephric duct morphogenesis
Biological Processpositive regulation of amyloid-beta formation
Biological Processpositive regulation of cell adhesion
Biological Processpositive regulation of cell migration
Biological Processpositive regulation of cell population proliferation
Biological Processprotein stabilization
Biological Processregulation of astrocyte differentiation
Biological Processregulation of axonogenesis
Biological Processregulation of dendritic spine morphogenesis
Biological Processregulation of modification of synaptic structure
Biological Processsynapse pruning

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    receptor protein-tyrosine kinase
  • EC number

Gene names

    • Name
      EPHA4

Organism names

Accessions

  • Primary accession
    K7FBC9

Proteomes

Subcellular Location

Cell membrane
; Single-pass type I membrane protein
Early endosome
Endosome
Membrane
; Single-pass type I membrane protein

Features

Showing features for transmembrane.

TypeIDPosition(s)Description
Transmembrane518-540Helical

Keywords

PTM/Processing

Features

Showing features for disulfide bond.

TypeIDPosition(s)Description
Disulfide bond43↔161
Disulfide bond78↔88

Keywords

Interaction

Protein-protein interaction databases

Family & Domains

Features

Showing features for domain.

TypeIDPosition(s)Description
Domain1-179Eph LBD
Domain298-409Fibronectin type-III
Domain410-507Fibronectin type-III
Domain591-852Protein kinase
Domain881-945SAM

Keywords

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    956
  • Mass (Da)
    106,640
  • Last updated
    2013-01-09 v1
  • Checksum
    7B24A741E8DE99AE
VTLLDSRSVQGELGWIASPLEGGWEEVSIMDEKNTPIRTYQVCNVMEPSQNNWLRTDWIPREGAQRVYIEIKFTLRDCNSLPGVMGTCKETFNLYYYESNNDKERYIRESQFAKIDTIAADESFTQVDIGDRIMKLNTEIRDVGPLSKKGFYLAFQDVGACIALVSVRVFYKKCPLTVRNLAQFPDTITGADTSSLVEVRGSCVNNSEEKDVPKMYCGADGEWLVPIGNCLCNAGYDEHNGECQACKIGYYKALSTDVSCAKCPSHSYSIWEGSTSCTCDRGFFRAENDAASMPCTRPPSAPLNLISNVNETSVNLEWSAPQNSGGRDDISYNVVCKRCGAGDLNRCRSCGSGVHFSPQQNGLKTTKVSITDLLAHSNYTFEIWAVNGVSKQNPSQDQAVSVTVTTNQAAPSPIALIQAKEITRHSVALAWLEPDRPNGVILEYEVKYYEKDQNERSYRIVKTASRNTDIKGLNPLTSYVFHVRARTAAGYGDFSGPFEFTTNTVPSPIIGDGTNPTVLLVSVAGSVVLVVILIAAFVISRRRSKYSKAKQEADEEKHLNQGVRTYVDPFTYEDPNQAVREFAKEIDASCIKIEKVIGVGEFGEVCSGRLKVPGKREICVAIKTLKAGYTDKQRRDFLSEASIMGQFDHPNIIHLEGVVTKCKPVMIITEYMENGSLDAFLRKNDGRFTVIQLVGMLRGIGSGMKYLSDMSYVHRDLAARNILVNSNLVCKVSDFGMSRVLEDDPEAAYTTRGGKIPIRWTAPEAIAYRKFTSASDVWSYGIVMWEVMSYGERPYWDMSNQDVIKAIEEGYRLPPPMDCPIALHQLMLDCWQKERSDRPKFGQIVNMLDKLIRNPNSLKRTGTENSRPNTALLDPSSPEFSAVVSVGDWLQAIKMDRYKDNFTAAGYTTLEAVVHMNQDDLTRIGITTIAHQNKILGNVQAMRTQMQQMHGRMVPV

Keywords

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
AGCU01164811
EMBL· GenBank· DDBJ
-Genomic DNA No translation available.
AGCU01164812
EMBL· GenBank· DDBJ
-Genomic DNA No translation available.
AGCU01164813
EMBL· GenBank· DDBJ
-Genomic DNA No translation available.
AGCU01164814
EMBL· GenBank· DDBJ
-Genomic DNA No translation available.
AGCU01164815
EMBL· GenBank· DDBJ
-Genomic DNA No translation available.
AGCU01164816
EMBL· GenBank· DDBJ
-Genomic DNA No translation available.
AGCU01164817
EMBL· GenBank· DDBJ
-Genomic DNA No translation available.
AGCU01164818
EMBL· GenBank· DDBJ
-Genomic DNA No translation available.
AGCU01164819
EMBL· GenBank· DDBJ
-Genomic DNA No translation available.

Genome annotation databases

Similar Proteins

Disclaimer

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