K7ESM2 · K7ESM2_HUMAN

  • Protein
    Protein HEXIM2
  • Gene
    HEXIM2
  • Status
    UniProtKB unreviewed (TrEMBL)
  • Amino acids
  • Protein existence
    Evidence at protein level
  • Annotation score
    2/5

Function

GO annotations

all annotationsall molecular functionvirus receptor activitydna bindingrna bindingcytoskeletal motor activitycatalytic activitygtpase activitystructural molecule activitytransporter activitycytoskeletal protein bindinglipid bindingcyclase activityantioxidant activityoxidoreductase activitytransferase activityhydrolase activitylyase activityisomerase activityligase activityprotein tag activitycargo receptor activityhistone bindingprotein folding chaperonetranslation regulator activitynutrient reservoir activityreceptor ligand activitymolecular transducer activitymolecular adaptor activitytoxin activitycell adhesion mediator activitymolecular function regulator activityvirus coreceptor activitycatalytic activity, acting on a proteincatalytic activity, acting on dnacatalytic activity, acting on rnamolecular carrier activitytranscription regulator activitygeneral transcription initiation factor activitymolecular sensor activitymolecular sequestering activityatp-dependent activityother molecular functionall biological processmitotic cell cyclecytokinesiscytoplasmic translationimmune system processmuscle system processcirculatory system processrenal system processrespiratory system processcarbohydrate metabolic processgeneration of precursor metabolites and energydna replicationdna repairdna recombinationchromatin organizationdna-templated transcriptionregulation of dna-templated transcriptiontrna metabolic processprotein foldingprotein glycosylationamino acid metabolic processmodified amino acid metabolic processlipid metabolic processvitamin metabolic processsulfur compound metabolic processintracellular protein transportnucleocytoplasmic transportautophagyinflammatory responsemitochondrion organizationcytoskeleton organizationmicrotubule-based movementperoxisome organizationlysosome organizationchromosome segregationcell adhesionestablishment or maintenance of cell polarityprogrammed cell deathphotosynthesismrna metabolic processsnrna metabolic processvesicle-mediated transportreproductive processdigestive system processsignalingcell differentiationprotein catabolic processextracellular matrix organizationregulatory ncrna-mediated gene silencingtelomere organizationcell junction organizationwound healingribosome biogenesiscilium organizationanatomical structure developmentcell motilitynervous system processendocrine processprotein maturationtransmembrane transportnucleobase-containing small molecule metabolic processhepaticobiliary system processmembrane organizationprotein-containing complex assemblycell wall organization or biogenesisnitrogen cycle metabolic processprotein localization to plasma membranedefense response to other organismdetoxificationmeiotic nuclear divisionmitotic nuclear divisionmitochondrial gene expressioncarbohydrate derivative metabolic processother biological processall cellular componentnuclear chromosomeextracellular regionextracellular spacecell wallnucleusnuclear envelopenucleoplasmchromosomenucleolusmitochondrionlysosomeendosomevacuoleperoxisomeendoplasmic reticulumgolgi apparatuslipid dropletmicrotubule organizing centercytosolribosomecytoskeletonplasma membraneciliumplastidthylakoidexternal encapsulating structureextracellular matrixcytoplasmic vesicleorganelleother cellular component
Cell color indicative of number of GO terms
AspectTerm
Cellular Componentcytosol
Cellular Componentnuclear speck
Cellular Componentnucleoplasm
Molecular Functioncyclin-dependent protein serine/threonine kinase inhibitor activity
Molecular FunctionsnRNA binding
Biological Processnegative regulation of transcription by RNA polymerase II

Subcellular Location

Keywords

  • Cellular component

Disease & Variants

Variants

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The viewer provides 351 variants from UniProt as well as other sources including ClinVar and dbSNP.

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Organism-specific databases

Genetic variation databases

PTM/Processing

Features

Showing features for modified residue (large scale data).

TypeIDPosition(s)SourceDescription
Modified residue (large scale data)4PRIDEPhosphothreonine
Modified residue (large scale data)14PRIDEPhosphoserine
Modified residue (large scale data)29PRIDEPhosphoserine
Modified residue (large scale data)32PRIDEPhosphothreonine
Modified residue (large scale data)39PRIDEPhosphoserine
Modified residue (large scale data)42PRIDEPhosphoserine
Modified residue (large scale data)46PRIDEPhosphothreonine
Modified residue (large scale data)51PRIDEPhosphoserine
Modified residue (large scale data)53PRIDEPhosphoserine
Modified residue (large scale data)69PRIDEPhosphoserine
Modified residue (large scale data)71PRIDEPhosphoserine
Modified residue (large scale data)74PRIDEPhosphothreonine
Modified residue (large scale data)76PRIDEPhosphoserine
Modified residue (large scale data)81PRIDEPhosphoserine

Proteomic databases

Expression

Gene expression databases

Structure

Family & Domains

Features

Showing features for region, compositional bias.

TypeIDPosition(s)Description
Region1-122Disordered
Compositional bias87-101Basic residues
Compositional bias102-122Basic and acidic residues

Sequence similarities

Belongs to the HEXIM family.

Keywords

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Fragment
  • Length
    122
  • Mass (Da)
    13,425
  • Last updated
    2013-01-09 v1
  • Checksum
    5F3EEA4CA524705D
MMATPNQTACNAESPVALEEAKTSGAPGSPQTPPERHDSGGSLPLTPRMESHSEDEDLAGAVGGLGWNSRSPRTQSPGGCSAEAVLARKKHRRRPSKRKRHWRPYLELSWAEKQQRDERQSQ

Computationally mapped potential isoform sequences

There are 5 potential isoforms mapped to this entry

View all
EntryEntry nameGene nameLength
Q96MH2HEXI2_HUMANHEXIM2286
K7EJA3K7EJA3_HUMANHEXIM2144
K7EIM4K7EIM4_HUMANHEXIM279
K7ELS4K7ELS4_HUMANHEXIM2139
K7ERG7K7ERG7_HUMANHEXIM2203

Features

Showing features for compositional bias, non-terminal residue.

TypeIDPosition(s)Description
Compositional bias87-101Basic residues
Compositional bias102-122Basic and acidic residues
Non-terminal residue122

Keywords

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
AC138150
EMBL· GenBank· DDBJ
-Genomic DNA No translation available.

Genome annotation databases

Similar Proteins

Disclaimer

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