K7ENW7 · K7ENW7_HUMAN
- ProteinDNA (cytosine-5-)-methyltransferase
- GeneDNMT1
- StatusUniProtKB unreviewed (TrEMBL)
- Organism
- Amino acids389 (go to sequence)
- Protein existenceEvidence at protein level
- Annotation score2/5
Function
Features
Showing features for active site.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Active site | 2 | |||||
Sequence: C |
GO annotations
all annotations | all molecular function | virus receptor activity | dna binding | rna binding | cytoskeletal motor activity | catalytic activity | gtpase activity | structural molecule activity | transporter activity | cytoskeletal protein binding | lipid binding | cyclase activity | antioxidant activity | oxidoreductase activity | transferase activity | hydrolase activity | lyase activity | isomerase activity | ligase activity | protein tag activity | cargo receptor activity | histone binding | protein folding chaperone | translation regulator activity | nutrient reservoir activity | receptor ligand activity | molecular transducer activity | molecular adaptor activity | toxin activity | cell adhesion mediator activity | molecular function regulator activity | virus coreceptor activity | catalytic activity, acting on a protein | catalytic activity, acting on dna | catalytic activity, acting on rna | molecular carrier activity | transcription regulator activity | general transcription initiation factor activity | molecular sensor activity | molecular sequestering activity | atp-dependent activity | other molecular function | all biological process | mitotic cell cycle | cytokinesis | cytoplasmic translation | immune system process | muscle system process | circulatory system process | renal system process | respiratory system process | carbohydrate metabolic process | generation of precursor metabolites and energy | dna replication | dna repair | dna recombination | chromatin organization | dna-templated transcription | regulation of dna-templated transcription | trna metabolic process | protein folding | protein glycosylation | amino acid metabolic process | modified amino acid metabolic process | lipid metabolic process | vitamin metabolic process | sulfur compound metabolic process | intracellular protein transport | nucleocytoplasmic transport | autophagy | inflammatory response | mitochondrion organization | cytoskeleton organization | microtubule-based movement | peroxisome organization | lysosome organization | chromosome segregation | cell adhesion | establishment or maintenance of cell polarity | programmed cell death | photosynthesis | mrna metabolic process | snrna metabolic process | vesicle-mediated transport | reproductive process | digestive system process | signaling | cell differentiation | protein catabolic process | extracellular matrix organization | regulatory ncrna-mediated gene silencing | telomere organization | cell junction organization | wound healing | ribosome biogenesis | cilium organization | anatomical structure development | cell motility | nervous system process | endocrine process | protein maturation | transmembrane transport | nucleobase-containing small molecule metabolic process | hepaticobiliary system process | membrane organization | protein-containing complex assembly | cell wall organization or biogenesis | nitrogen cycle metabolic process | protein localization to plasma membrane | defense response to other organism | detoxification | meiotic nuclear division | mitotic nuclear division | mitochondrial gene expression | carbohydrate derivative metabolic process | other biological process | all cellular component | nuclear chromosome | extracellular region | extracellular space | cell wall | nucleus | nuclear envelope | nucleoplasm | chromosome | nucleolus | mitochondrion | lysosome | endosome | vacuole | peroxisome | endoplasmic reticulum | golgi apparatus | lipid droplet | microtubule organizing center | cytosol | ribosome | cytoskeleton | plasma membrane | cilium | plastid | thylakoid | external encapsulating structure | extracellular matrix | cytoplasmic vesicle | organelle | other cellular component | |||
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Aspect | Term | |
---|---|---|
Molecular Function | methyltransferase activity | |
Biological Process | methylation |
Keywords
- Molecular function
- Ligand
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended nameDNA (cytosine-5-)-methyltransferase
- EC number
Gene names
Organism names
- Organism
- Taxonomic lineageEukaryota > Metazoa > Chordata > Craniata > Vertebrata > Euteleostomi > Mammalia > Eutheria > Euarchontoglires > Primates > Haplorrhini > Catarrhini > Hominidae > Homo
Accessions
- Primary accessionK7ENW7
Proteomes
Organism-specific databases
Disease & Variants
Variants
We now provide the "Disease & Variants" viewer in its own tab.
The viewer provides 255 variants from UniProt as well as other sources including ClinVar and dbSNP.
Genetic variation databases
PTM/Processing
Proteomic databases
Expression
Gene expression databases
Structure
Sequence
- Sequence statusFragment
- Length389
- Mass (Da)43,389
- Last updated2013-01-09 v1
- Checksum00CD4BB3D6A2C2F6
Computationally mapped potential isoform sequences
There are 19 potential isoforms mapped to this entry
Entry | Entry name | Gene name | Length | ||
---|---|---|---|---|---|
P26358 | DNMT1_HUMAN | DNMT1 | 1616 | ||
K7EIZ6 | K7EIZ6_HUMAN | DNMT1 | 40 | ||
K7EKC3 | K7EKC3_HUMAN | DNMT1 | 25 | ||
K7EJL0 | K7EJL0_HUMAN | DNMT1 | 255 | ||
K7ELB1 | K7ELB1_HUMAN | DNMT1 | 94 | ||
K7ENQ6 | K7ENQ6_HUMAN | DNMT1 | 119 | ||
K7EMU8 | K7EMU8_HUMAN | DNMT1 | 89 | ||
K7EP77 | K7EP77_HUMAN | DNMT1 | 55 | ||
K7ER10 | K7ER10_HUMAN | DNMT1 | 77 | ||
K7ERQ1 | K7ERQ1_HUMAN | DNMT1 | 71 | ||
A0A7I2YQA8 | A0A7I2YQA8_HUMAN | DNMT1 | 1577 | ||
A0A7I2YQQ0 | A0A7I2YQQ0_HUMAN | DNMT1 | 1613 | ||
A0A7I2V2G5 | A0A7I2V2G5_HUMAN | DNMT1 | 263 | ||
A0A7I2V311 | A0A7I2V311_HUMAN | DNMT1 | 1150 | ||
A0A7I2V3F8 | A0A7I2V3F8_HUMAN | DNMT1 | 184 | ||
A0A7I2V490 | A0A7I2V490_HUMAN | DNMT1 | 1658 | ||
A0A7I2V5F1 | A0A7I2V5F1_HUMAN | DNMT1 | 1580 | ||
A0A7I2V5F6 | A0A7I2V5F6_HUMAN | DNMT1 | 1114 | ||
A0A7I2V5D0 | A0A7I2V5D0_HUMAN | DNMT1 | 1655 |
Features
Showing features for non-terminal residue.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Non-terminal residue | 1 | |||||
Sequence: X |
Keywords
- Technical term
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
AC010077 EMBL· GenBank· DDBJ | - | Genomic DNA | No translation available. | |
AC011511 EMBL· GenBank· DDBJ | - | Genomic DNA | No translation available. | |
AC020931 EMBL· GenBank· DDBJ | - | Genomic DNA | No translation available. |