K7CMA3 · K7CMA3_PANTR
- ProteinPhospholipid-transporting ATPase
- GeneATP10A
- StatusUniProtKB unreviewed (TrEMBL)
- Organism
- Amino acids1499 (go to sequence)
- Protein existenceEvidence at transcript level
- Annotation score3/5
Function
Catalytic activity
Cofactor
GO annotations
all annotations | all molecular function | virus receptor activity | dna binding | rna binding | cytoskeletal motor activity | catalytic activity | gtpase activity | structural molecule activity | transporter activity | cytoskeletal protein binding | lipid binding | cyclase activity | antioxidant activity | oxidoreductase activity | transferase activity | hydrolase activity | lyase activity | isomerase activity | ligase activity | protein tag activity | cargo receptor activity | histone binding | protein folding chaperone | translation regulator activity | nutrient reservoir activity | receptor ligand activity | molecular transducer activity | molecular adaptor activity | toxin activity | cell adhesion mediator activity | molecular function regulator activity | virus coreceptor activity | catalytic activity, acting on a protein | catalytic activity, acting on dna | catalytic activity, acting on rna | molecular carrier activity | transcription regulator activity | general transcription initiation factor activity | molecular sensor activity | molecular sequestering activity | atp-dependent activity | other molecular function | all biological process | mitotic cell cycle | cytokinesis | cytoplasmic translation | immune system process | muscle system process | circulatory system process | renal system process | respiratory system process | carbohydrate metabolic process | generation of precursor metabolites and energy | dna replication | dna repair | dna recombination | chromatin organization | dna-templated transcription | regulation of dna-templated transcription | trna metabolic process | protein folding | protein glycosylation | amino acid metabolic process | modified amino acid metabolic process | lipid metabolic process | vitamin metabolic process | sulfur compound metabolic process | intracellular protein transport | nucleocytoplasmic transport | autophagy | inflammatory response | mitochondrion organization | cytoskeleton organization | microtubule-based movement | peroxisome organization | lysosome organization | chromosome segregation | cell adhesion | establishment or maintenance of cell polarity | programmed cell death | photosynthesis | mrna metabolic process | snrna metabolic process | vesicle-mediated transport | reproductive process | digestive system process | signaling | cell differentiation | protein catabolic process | extracellular matrix organization | regulatory ncrna-mediated gene silencing | telomere organization | cell junction organization | wound healing | ribosome biogenesis | cilium organization | anatomical structure development | cell motility | nervous system process | endocrine process | protein maturation | transmembrane transport | nucleobase-containing small molecule metabolic process | hepaticobiliary system process | membrane organization | protein-containing complex assembly | cell wall organization or biogenesis | nitrogen cycle metabolic process | protein localization to plasma membrane | defense response to other organism | detoxification | meiotic nuclear division | mitotic nuclear division | mitochondrial gene expression | carbohydrate derivative metabolic process | other biological process | all cellular component | nuclear chromosome | extracellular region | extracellular space | cell wall | nucleus | nuclear envelope | nucleoplasm | chromosome | nucleolus | mitochondrion | lysosome | endosome | vacuole | peroxisome | endoplasmic reticulum | golgi apparatus | lipid droplet | microtubule organizing center | cytosol | ribosome | cytoskeleton | plasma membrane | cilium | plastid | thylakoid | external encapsulating structure | extracellular matrix | cytoplasmic vesicle | organelle | other cellular component | |||
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Aspect | Term | |
---|---|---|
Cellular Component | endoplasmic reticulum | |
Cellular Component | phospholipid-translocating ATPase complex | |
Cellular Component | plasma membrane | |
Molecular Function | ATP binding | |
Molecular Function | ATP hydrolysis activity | |
Molecular Function | ATPase-coupled intramembrane lipid transporter activity | |
Molecular Function | glycosylceramide flippase activity | |
Molecular Function | magnesium ion binding | |
Molecular Function | phosphatidylcholine flippase activity | |
Biological Process | phospholipid translocation | |
Biological Process | positive regulation of membrane tubulation |
Keywords
- Molecular function
- Biological process
- Ligand
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended namePhospholipid-transporting ATPase
- EC number
Gene names
Organism names
- Organism
- Taxonomic lineageEukaryota > Metazoa > Chordata > Craniata > Vertebrata > Euteleostomi > Mammalia > Eutheria > Euarchontoglires > Primates > Haplorrhini > Catarrhini > Hominidae > Pan
Accessions
- Primary accessionK7CMA3
- Secondary accessions
Proteomes
Organism-specific databases
Subcellular Location
UniProt Annotation
GO Annotation
Membrane ; Multi-pass membrane protein
Features
Showing features for transmembrane.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Transmembrane | 87-104 | Helical | ||||
Sequence: ANVYFVFIALLNFVPAVN | ||||||
Transmembrane | 110-128 | Helical | ||||
Sequence: LALAPVLFILAITAFRDLW | ||||||
Transmembrane | 310-333 | Helical | ||||
Sequence: VLWCVLLLVCMSLFSAVGHGLWIW | ||||||
Transmembrane | 357-379 | Helical | ||||
Sequence: AAVYSFLTMIIVLQVLIPISLYV | ||||||
Transmembrane | 1092-1114 | Helical | ||||
Sequence: FFYKNTMFVGLLFWFQFFCGFSA | ||||||
Transmembrane | 1120-1141 | Helical | ||||
Sequence: QWYLIFFNLLFSSLPPLVTGVL | ||||||
Transmembrane | 1171-1194 | Helical | ||||
Sequence: FWFNMADAAFQSLVCFSIPYLAYY | ||||||
Transmembrane | 1200-1221 | Helical | ||||
Sequence: LFTWGTPIVTIALLTFLLHLGI | ||||||
Transmembrane | 1228-1248 | Helical | ||||
Sequence: WLNWITCGFSVLLFFTVALIY | ||||||
Transmembrane | 1273-1292 | Helical | ||||
Sequence: VFYLTCLMTPVAALLPRLFF |
Keywords
- Cellular component
PTM/Processing
Proteomic databases
Expression
Gene expression databases
Interaction
Protein-protein interaction databases
Structure
Family & Domains
Features
Showing features for compositional bias, region, domain.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Compositional bias | 1-17 | Basic and acidic residues | ||||
Sequence: MEREPAGTEEPGPPGRR | ||||||
Region | 1-53 | Disordered | ||||
Sequence: MEREPAGTEEPGPPGRRRRREGRTRTVRSNLLPPPGAEDPAAGAAKGERRRRR | ||||||
Domain | 57-109 | P-type ATPase N-terminal | ||||
Sequence: QHLADNRLKTTKYTLLSFLPKNLFEQFHRPANVYFVFIALLNFVPAVNAFQPG | ||||||
Region | 464-531 | Disordered | ||||
Sequence: ADSEEEEVVPRGGSVSQRGSIGSHQSVRVVHRTQSTKSHRRTGSRAEAKRASMLSKHTAFSSPMEKDI | ||||||
Compositional bias | 479-495 | Polar residues | ||||
Sequence: SQRGSIGSHQSVRVVHR | ||||||
Domain | 1057-1302 | P-type ATPase C-terminal | ||||
Sequence: VMASDFAVPKFRYLERLLILHGHWCYSRLANMVLYFFYKNTMFVGLLFWFQFFCGFSASAMIDQWYLIFFNLLFSSLPPLVTGVLDRDVPANVLLTNPQVYKSGQNMEEYRPRTFWFNMADAAFQSLVCFSIPYLAYYDSSVDLFTWGTPIVTIALLTFLLHLGIETKTWTWLNWITCGFSVLLFFTVALIYNASCATCYPPSNPYWTMQALLGDPVFYLTCLMTPVAALLPRLFFRSLQGSVFPT | ||||||
Region | 1311-1359 | Disordered | ||||
Sequence: TRKSPRRCSAPKETFAQGRLPKDSGTEHSSGRTVKTSVPLSQPSWHTQQ | ||||||
Compositional bias | 1340-1359 | Polar residues | ||||
Sequence: SGRTVKTSVPLSQPSWHTQQ | ||||||
Region | 1393-1413 | Disordered | ||||
Sequence: PMSSAPGEAVLRSPGGCPEES | ||||||
Region | 1465-1499 | Disordered | ||||
Sequence: GQAGRGLPVQPHSGRSGLQGPDHRLLIGASSRRSQ |
Sequence similarities
Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IV subfamily.
Keywords
- Domain
Phylogenomic databases
Family and domain databases
Sequence
- Sequence statusComplete
- Length1,499
- Mass (Da)167,682
- Last updated2013-01-09 v1
- Checksum8C86EFF9573872D2
Computationally mapped potential isoform sequences
There is 1 potential isoform mapped to this entry
Entry | Entry name | Gene name | Length | ||
---|---|---|---|---|---|
A0A2J8KLJ8 | A0A2J8KLJ8_PANTR | ATP10A | 155 |
Features
Showing features for compositional bias.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Compositional bias | 1-17 | Basic and acidic residues | ||||
Sequence: MEREPAGTEEPGPPGRR | ||||||
Compositional bias | 479-495 | Polar residues | ||||
Sequence: SQRGSIGSHQSVRVVHR | ||||||
Compositional bias | 1340-1359 | Polar residues | ||||
Sequence: SGRTVKTSVPLSQPSWHTQQ |
Keywords
- Technical term
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
AACZ04047720 EMBL· GenBank· DDBJ | - | Genomic DNA | No translation available. | |
AACZ04047721 EMBL· GenBank· DDBJ | - | Genomic DNA | No translation available. | |
GABC01003487 EMBL· GenBank· DDBJ | JAA07851.1 EMBL· GenBank· DDBJ | mRNA | ||
GABF01000454 EMBL· GenBank· DDBJ | JAA21691.1 EMBL· GenBank· DDBJ | mRNA | ||
GABD01005626 EMBL· GenBank· DDBJ | JAA27474.1 EMBL· GenBank· DDBJ | mRNA |