K6BWP5 · K6BWP5_SCHAZ

Function

function

Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis: the synthesis of N-acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N2-acetylornithine and glutamate.

Miscellaneous

Some bacteria possess a monofunctional ArgJ, i.e., capable of catalyzing only the fifth step of the arginine biosynthetic pathway.

Caution

The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

Catalytic activity

Pathway

Amino-acid biosynthesis; L-arginine biosynthesis; L-ornithine and N-acetyl-L-glutamate from L-glutamate and N2-acetyl-L-ornithine (cyclic): step 1/1.
Amino-acid biosynthesis; L-arginine biosynthesis; N2-acetyl-L-ornithine from L-glutamate: step 1/4.

Features

Showing features for site, binding site, active site.

Type
IDPosition(s)Description
Site127Involved in the stabilization of negative charge on the oxyanion by the formation of the oxyanion hole
Site128Involved in the stabilization of negative charge on the oxyanion by the formation of the oxyanion hole
Binding site164substrate
Binding site190substrate
Site200-201Cleavage; by autolysis
Active site201Nucleophile
Binding site201substrate
Binding site287substrate
Binding site409substrate
Binding site414substrate

GO annotations

AspectTerm
Cellular Componentcytoplasm
Molecular Functionglutamate N-acetyltransferase activity
Molecular FunctionL-glutamate N-acetyltransferase activity
Biological Processarginine biosynthetic process
Biological Processornithine biosynthetic process

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

Including 2 domains:

  • Recommended name
    Glutamate N-acetyltransferase
  • EC number
  • Alternative names
    • Ornithine acetyltransferase
      (OATase
      )
    • Ornithine transacetylase
  • Recommended name
    Amino-acid acetyltransferase
  • EC number
  • Alternative names
    • N-acetylglutamate synthase
      (AGSase
      )

Gene names

    • Name
      argJ
    • ORF names
      BAZO_16874

Organism names

  • Taxonomic identifier
  • Strain
    • LMG 9581
  • Taxonomic lineage
    Bacteria > Bacillota > Bacilli > Bacillales > Bacillaceae > Calidifontibacillus/Schinkia group > Schinkia

Accessions

  • Primary accession
    K6BWP5

Proteomes

Subcellular Location

Keywords

PTM/Processing

Features

Showing features for chain.

TypeIDPosition(s)Description
ChainPRO_50235330961-200Arginine biosynthesis bifunctional protein ArgJ alpha chain
ChainPRO_5023533097201-414Arginine biosynthesis bifunctional protein ArgJ beta chain

Keywords

Interaction

Subunit

Heterotetramer of two alpha and two beta chains.

Protein-protein interaction databases

Family & Domains

Sequence similarities

Belongs to the ArgJ family.

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    414
  • Mass (Da)
    44,232
  • Last updated
    2013-01-09 v1
  • MD5 Checksum
    FC9B13685D230D19B825BC72B524DAA7
MILEGRSNVSKRFKKVENGSVTSPKGYSATGIYANLRKKDKLDLAIILSEVPASCAAVYTLNAFQAAPLKITKDSIAKEGKLQAVICNSGNANACTGEQGEKDAIRIRKEVSEKFSLKEHYIAVASTGVIGELMPMDKISAGIEQLSPVPSIEGGDLFSKAILTTDLVAKTTCYEIVVNGKTVTIAGAAKGSGMIHPNMATMLGFVTTDANIESKDLQYALSDITNKTFNRITVDGDTSTNDMVLVMANGMAENESLTTDHPDWEVFYQALQMACEDLAKEIARDGEGATKLVEVQVEGALSDEDAGKIAKSVVGSSLVKTAVFGADANWGRIICAVGYTGVEVNPSLVDVFIGDIQMLKAGQPIPFSEEDATLYLKGKEVVIKVNLHIGEGEGKAWGCDLSYDYVRINGSYRS

Keywords

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
AJLR01000146
EMBL· GenBank· DDBJ
EKN63365.1
EMBL· GenBank· DDBJ
Genomic DNA

Genome annotation databases

Similar Proteins

Disclaimer

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