K5X304 · K5X304_AGABU
- ProteinSphingomyelin phosphodiesterase
- StatusUniProtKB unreviewed (TrEMBL)
- Amino acids632 (go to sequence)
- Protein existenceInferred from homology
- Annotation score2/5
Function
function
Converts sphingomyelin to ceramide.
Cofactor
Note: Binds 2 Zn2+ ions per subunit.
Features
Showing features for binding site.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Binding site | 150 | Zn2+ 1 (UniProtKB | ChEBI) | |||
Binding site | 152 | Zn2+ 1 (UniProtKB | ChEBI) | |||
Binding site | 221 | Zn2+ 1 (UniProtKB | ChEBI) | |||
Binding site | 221 | Zn2+ 2 (UniProtKB | ChEBI) | |||
Binding site | 260 | Zn2+ 2 (UniProtKB | ChEBI) | |||
Binding site | 372 | Zn2+ 2 (UniProtKB | ChEBI) | |||
Binding site | 406 | Zn2+ 2 (UniProtKB | ChEBI) | |||
Binding site | 408 | Zn2+ 1 (UniProtKB | ChEBI) | |||
GO annotations
Aspect | Term | |
---|---|---|
Cellular Component | extracellular space | |
Molecular Function | hydrolase activity, acting on glycosyl bonds | |
Molecular Function | metal ion binding | |
Molecular Function | sphingomyelin phosphodiesterase activity | |
Biological Process | sphingomyelin catabolic process |
Keywords
- Molecular function
- Ligand
Names & Taxonomy
Protein names
- Recommended nameSphingomyelin phosphodiesterase
Gene names
Organism names
- Strain
- Taxonomic lineageEukaryota > Fungi > Dikarya > Basidiomycota > Agaricomycotina > Agaricomycetes > Agaricomycetidae > Agaricales > Agaricineae > Agaricaceae > Agaricus
Accessions
- Primary accessionK5X304
Proteomes
Subcellular Location
UniProt Annotation
GO Annotation
PTM/Processing
Features
Showing features for signal, chain, disulfide bond.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Signal | 1-21 | ||||
Chain | PRO_5003891030 | 22-632 | Sphingomyelin phosphodiesterase | ||
Disulfide bond | 66↔77 | ||||
Disulfide bond | 165↔170 | ||||
Disulfide bond | 171↔194 | ||||
Keywords
- PTM
Interaction
Protein-protein interaction databases
Structure
Family & Domains
Features
Showing features for domain.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Domain | 144-409 | Calcineurin-like phosphoesterase | |||
Sequence similarities
Belongs to the acid sphingomyelinase family.
Keywords
- Domain
Phylogenomic databases
Family and domain databases
Sequence
- Sequence statusComplete
- Length632
- Mass (Da)69,288
- Last updated2013-01-09 v1
- ChecksumE7A1BC60BAE2C4F1
Keywords
- Technical term
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
JH971396 EMBL· GenBank· DDBJ | EKM77297.1 EMBL· GenBank· DDBJ | Genomic DNA |