K5X1T0 · K5X1T0_AGABU
- ProteinDolichyl-phosphate-mannose--protein mannosyltransferase
- StatusUniProtKB unreviewed (TrEMBL)
- Amino acids780 (go to sequence)
- Protein existenceInferred from homology
- Annotation score2/5
Function
function
Transfers mannose from Dol-P-mannose to Ser or Thr residues on proteins.
Catalytic activity
- a di-trans,poly-cis-dolichyl beta-D-mannosyl phosphate + L-seryl-[protein] = 3-O-(alpha-D-mannosyl)-L-seryl-[protein] + a di-trans,poly-cis-dolichyl phosphate + H+
a di-trans,poly-cis-dolichyl β-D-mannosyl phosphate RHEA-COMP:19501 + RHEA-COMP:9863 = RHEA-COMP:13546 + a di-trans,poly-cis-dolichyl phosphate RHEA-COMP:19498 + CHEBI:15378
Pathway
Protein modification; protein glycosylation.
GO annotations
Aspect | Term | |
---|---|---|
Cellular Component | endoplasmic reticulum membrane | |
Molecular Function | dolichyl-phosphate-mannose-protein mannosyltransferase activity |
Keywords
- Molecular function
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended nameDolichyl-phosphate-mannose--protein mannosyltransferase
- EC number
Gene names
Organism names
- Strain
- Taxonomic lineageEukaryota > Fungi > Dikarya > Basidiomycota > Agaricomycotina > Agaricomycetes > Agaricomycetidae > Agaricales > Agaricineae > Agaricaceae > Agaricus
Accessions
- Primary accessionK5X1T0
Proteomes
Subcellular Location
UniProt Annotation
GO Annotation
Endoplasmic reticulum membrane ; Multi-pass membrane protein
Features
Showing features for transmembrane.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Transmembrane | 61-80 | Helical | |||
Transmembrane | 107-127 | Helical | |||
Transmembrane | 147-168 | Helical | |||
Transmembrane | 175-195 | Helical | |||
Transmembrane | 201-221 | Helical | |||
Transmembrane | 233-250 | Helical | |||
Transmembrane | 256-273 | Helical | |||
Transmembrane | 293-315 | Helical | |||
Transmembrane | 610-632 | Helical | |||
Transmembrane | 653-670 | Helical | |||
Transmembrane | 682-705 | Helical | |||
Transmembrane | 726-745 | Helical | |||
Keywords
- Cellular component
Interaction
Protein-protein interaction databases
Structure
Family & Domains
Features
Showing features for region, compositional bias, domain.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Region | 1-36 | Disordered | |||
Compositional bias | 17-36 | Polar residues | |||
Domain | 341-401 | MIR | |||
Domain | 410-467 | MIR | |||
Domain | 471-527 | MIR | |||
Sequence similarities
Belongs to the glycosyltransferase 39 family.
Keywords
- Domain
Phylogenomic databases
Family and domain databases
Sequence
- Sequence statusComplete
- Length780
- Mass (Da)88,387
- Last updated2013-01-09 v1
- Checksum33EE24E2FF8EC6A4
Features
Showing features for compositional bias.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Compositional bias | 17-36 | Polar residues | |||
Keywords
- Technical term
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
JH971387 EMBL· GenBank· DDBJ | EKM81771.1 EMBL· GenBank· DDBJ | Genomic DNA |