K5W5Q7 · K5W5Q7_AGABU
- ProteinFructose-bisphosphate aldolase
- StatusUniProtKB unreviewed (TrEMBL)
- Amino acids358 (go to sequence)
- Protein existenceInferred from homology
- Annotation score2/5
Function
function
Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis.
Catalytic activity
- beta-D-fructose 1,6-bisphosphate = D-glyceraldehyde 3-phosphate + dihydroxyacetone phosphate
Cofactor
Note: Binds 2 Zn2+ ions per subunit. One is catalytic and the other provides a structural contribution.
Pathway
Carbohydrate degradation; glycolysis; D-glyceraldehyde 3-phosphate and glycerone phosphate from D-glucose: step 4/4.
GO annotations
Aspect | Term | |
---|---|---|
Cellular Component | cytosol | |
Molecular Function | fructose-bisphosphate aldolase activity | |
Molecular Function | zinc ion binding | |
Biological Process | gluconeogenesis | |
Biological Process | glycolytic process |
Keywords
- Molecular function
- Biological process
- Ligand
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended nameFructose-bisphosphate aldolase
- EC number
- Short namesFBP aldolase
Gene names
Organism names
- Strain
- Taxonomic lineageEukaryota > Fungi > Dikarya > Basidiomycota > Agaricomycotina > Agaricomycetes > Agaricomycetidae > Agaricales > Agaricineae > Agaricaceae > Agaricus
Accessions
- Primary accessionK5W5Q7
Proteomes
Subcellular Location
UniProt Annotation
GO Annotation
Interaction
Protein-protein interaction databases
Structure
Sequence
- Sequence statusComplete
- Length358
- Mass (Da)39,259
- Last updated2013-01-09 v1
- ChecksumC176FF44824277C4
Keywords
- Technical term
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
JH971387 EMBL· GenBank· DDBJ | EKM82139.1 EMBL· GenBank· DDBJ | Genomic DNA |