K5W5Q7 · K5W5Q7_AGABU

Function

function

Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis.

Catalytic activity

Cofactor

Zn2+ (UniProtKB | Rhea| CHEBI:29105 )

Note: Binds 2 Zn2+ ions per subunit. One is catalytic and the other provides a structural contribution.

Pathway

Carbohydrate degradation; glycolysis; D-glyceraldehyde 3-phosphate and glycerone phosphate from D-glucose: step 4/4.

GO annotations

AspectTerm
Cellular Componentcytosol
Molecular Functionfructose-bisphosphate aldolase activity
Molecular Functionzinc ion binding
Biological Processgluconeogenesis
Biological Processglycolytic process

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    Fructose-bisphosphate aldolase
  • EC number
  • Short names
    FBP aldolase

Gene names

    • ORF names
      AGABI1DRAFT_112255

Organism names

Accessions

  • Primary accession
    K5W5Q7

Proteomes

Subcellular Location

Interaction

Protein-protein interaction databases

Family & Domains

Sequence similarities

Belongs to the class II fructose-bisphosphate aldolase family.

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    358
  • Mass (Da)
    39,259
  • Last updated
    2013-01-09 v1
  • Checksum
    C176FF44824277C4
MGVLDIVPAGVLTGDNVRKLFDYAKANKFAIPAVNVTSTSVANAVLEAARDIKSPIIIQVSQGGAAYFAGKGLANDKQQASIVGAVSAAHHVRLMAKAYGIPVVMHSDHCAHKLLPWFDGMLQADEAYFNDHGEPLFSSHMLDLSEEPKEENIKICEKYFKRMAAIGIWLEMEIGITGGEEDGVDNSNVDNSSLYTQPADVFDVYKALHPISPNFSIAAAFGNVHGVYKPGNVRLRPELLAKHQEYAREQIGSKDSQPLYLVFHGGSGSLAEEIKTAVDNGVVKMNVDTDTQYAYLVGIRDFIEKKKGYLMSQVGNPEGEDKPNKKYYDPRVWVREGEKTLSERVKVACTNLGNVNRL

Keywords

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
JH971387
EMBL· GenBank· DDBJ
EKM82139.1
EMBL· GenBank· DDBJ
Genomic DNA

Genome annotation databases

Similar Proteins

Disclaimer

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