K5VP82 · K5VP82_AGABU
- ProteinCAAX prenyl protease
- StatusUniProtKB unreviewed (TrEMBL)
- Amino acids462 (go to sequence)
- Protein existenceInferred from homology
- Annotation score2/5
Function
function
Proteolytically removes the C-terminal three residues of farnesylated proteins.
Catalytic activity
Cofactor
Note: Binds 1 zinc ion per subunit.
Features
Showing features for binding site, active site.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Binding site | 303 | Zn2+ (UniProtKB | ChEBI); catalytic | |||
Active site | 304 | ||||
Binding site | 307 | Zn2+ (UniProtKB | ChEBI); catalytic | |||
Binding site | 386 | Zn2+ (UniProtKB | ChEBI); catalytic | |||
Active site | 390 | Proton donor | |||
GO annotations
Aspect | Term | |
---|---|---|
Cellular Component | endoplasmic reticulum membrane | |
Molecular Function | metal ion binding | |
Molecular Function | metalloendopeptidase activity | |
Biological Process | CAAX-box protein processing |
Keywords
- Molecular function
- Ligand
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended nameCAAX prenyl protease
- EC number
Gene names
Organism names
- Strain
- Taxonomic lineageEukaryota > Fungi > Dikarya > Basidiomycota > Agaricomycotina > Agaricomycetes > Agaricomycetidae > Agaricales > Agaricineae > Agaricaceae > Agaricus
Accessions
- Primary accessionK5VP82
Proteomes
Subcellular Location
UniProt Annotation
GO Annotation
Endoplasmic reticulum membrane ; Multi-pass membrane protein
Features
Showing features for transmembrane.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Transmembrane | 125-154 | Helical | |||
Transmembrane | 175-195 | Helical | |||
Transmembrane | 201-220 | Helical | |||
Transmembrane | 316-337 | Helical | |||
Transmembrane | 357-381 | Helical | |||
Keywords
- Cellular component
Interaction
Protein-protein interaction databases
Structure
Family & Domains
Features
Showing features for domain.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Domain | 47-230 | CAAX prenyl protease 1 N-terminal | |||
Domain | 234-452 | Peptidase M48 | |||
Sequence similarities
Belongs to the peptidase M48A family.
Keywords
- Domain
Phylogenomic databases
Family and domain databases
Sequence
- Sequence statusComplete
- Length462
- Mass (Da)52,852
- Last updated2013-01-09 v1
- Checksum3FDC50BB423514FC
Keywords
- Technical term
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
JH971403 EMBL· GenBank· DDBJ | EKM76274.1 EMBL· GenBank· DDBJ | Genomic DNA |