K4K2Q9 · K4K2Q9_THYTH

Function

function

Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex) that is part of the mitochondrial respiratory chain. The b-c1 complex mediates electron transfer from ubiquinol to cytochrome c. Contributes to the generation of a proton gradient across the mitochondrial membrane that is then used for ATP synthesis.

Cofactor

Protein has several cofactor binding sites:
heme b (UniProtKB | Rhea| CHEBI:60344 )

Note: Binds 2 heme groups non-covalently.
heme (UniProtKB | Rhea| CHEBI:30413 )

Note: Binds 2 heme groups non-covalently.

Features

Showing features for binding site.

138050100150200250300350
TypeIDPosition(s)Description
Binding site83Fe (UniProtKB | ChEBI) of heme b b562 (UniProtKB | ChEBI); axial binding residue
Binding site97Fe (UniProtKB | ChEBI) of heme b b566 (UniProtKB | ChEBI); axial binding residue
Binding site182Fe (UniProtKB | ChEBI) of heme b b562 (UniProtKB | ChEBI); axial binding residue
Binding site196Fe (UniProtKB | ChEBI) of heme b b566 (UniProtKB | ChEBI); axial binding residue
Binding site201a ubiquinone (UniProtKB | ChEBI)

GO annotations

AspectTerm
Cellular Componentmitochondrial inner membrane
Cellular Componentrespiratory chain complex III
Molecular Functionmetal ion binding
Molecular Functionubiquinol-cytochrome-c reductase activity
Biological Processmitochondrial electron transport, ubiquinol to cytochrome c

Keywords

Names & Taxonomy

Protein names

  • Recommended name
    Cytochrome b

Gene names

    • Name
      cytb
    • Synonyms
      CYTB

Encoded on

  • Mitochondrion

Organism names

  • Taxonomic identifier
  • Strains
    • #107
    • I05
    • KOLPA25
    • Loire_LacP
    • Mes41
  • Taxonomic lineage
    Eukaryota > Metazoa > Chordata > Craniata > Vertebrata > Euteleostomi > Actinopterygii > Neopterygii > Teleostei > Protacanthopterygii > Salmoniformes > Salmonidae > Thymallinae > Thymallus

Accessions

  • Primary accession
    K4K2Q9

Subcellular Location

Features

Showing features for transmembrane.

TypeIDPosition(s)Description
Transmembrane29-52Helical
Transmembrane87-107Helical
Transmembrane113-133Helical
Transmembrane145-166Helical
Transmembrane178-200Helical
Transmembrane229-250Helical
Transmembrane288-308Helical
Transmembrane320-341Helical
Transmembrane347-372Helical

Keywords

Family & Domains

Features

Showing features for domain.

TypeIDPosition(s)Description
Domain1-209Cytochrome b/b6 N-terminal region profile
Domain210-380Cytochrome b/b6 C-terminal region profile

Sequence similarities

Belongs to the cytochrome b family.

Keywords

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    380
  • Mass (Da)
    42,293
  • Last updated
    2013-01-09 v1
  • MD5 Checksum
    BD8E679B0AFC36648CEC5253338C13A5
MANLRKTHPLLKIANDALVDLPAPSNISVWWNFGSLLGLCLATQILTGLFLAMHYTSDISTAFSSVCHICRDVSYGWLIRNIHANGASFFFICIYMHIARGLYYGSYLYKETWNIGVVLLLLTMMTAFVGYVLPWGQMSFWGATVITNLLSAVPYVGGALVQWIWGGFSVDNATLTRFFAFHFLFPFVIAAATVLHLLFLHETGSNNPAGINSDADKISFHPYFSYKDLLGFVAMLLGLTSLALFAPNLLGDPDNFTPANPLVTPPHIKPEWYFLFAYAILRSIPNKLGGVLALLFSILVLMVVPILHTSKQRGLTFRPLTQFLFWTLVADMLILTWIGGMPVEHPFIIIGQVASVIYFTIFLILAPLAGWAENKALEWA

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
JX960869
EMBL· GenBank· DDBJ
AFU93295.1
EMBL· GenBank· DDBJ
Genomic DNA
MT062995
EMBL· GenBank· DDBJ
QPZ47157.1
EMBL· GenBank· DDBJ
Genomic DNA
MT062997
EMBL· GenBank· DDBJ
QPZ47183.1
EMBL· GenBank· DDBJ
Genomic DNA
MT062999
EMBL· GenBank· DDBJ
QPZ47209.1
EMBL· GenBank· DDBJ
Genomic DNA
MT063000
EMBL· GenBank· DDBJ
QPZ47222.1
EMBL· GenBank· DDBJ
Genomic DNA
MT063001
EMBL· GenBank· DDBJ
QPZ47235.1
EMBL· GenBank· DDBJ
Genomic DNA
MT063006
EMBL· GenBank· DDBJ
QPZ47300.1
EMBL· GenBank· DDBJ
Genomic DNA
MT063040
EMBL· GenBank· DDBJ
QPZ93721.1
EMBL· GenBank· DDBJ
Genomic DNA
MT063041
EMBL· GenBank· DDBJ
QPZ93734.1
EMBL· GenBank· DDBJ
Genomic DNA
MT063042
EMBL· GenBank· DDBJ
QPZ93747.1
EMBL· GenBank· DDBJ
Genomic DNA
MT063043
EMBL· GenBank· DDBJ
QPZ93760.1
EMBL· GenBank· DDBJ
Genomic DNA

Similar Proteins

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