J9F199 · J9F199_WUCBA

  • Protein
    dihydrofolate reductase
  • Status
    UniProtKB unreviewed (TrEMBL)
  • Amino acids
  • Protein existence
    Evidence at protein level
  • Annotation score
    2/5

Function

Catalytic activity

Pathway

Cofactor biosynthesis; tetrahydrofolate biosynthesis; 5,6,7,8-tetrahydrofolate from 7,8-dihydrofolate: step 1/1.

Features

Showing features for binding site.

117220406080100120140160
TypeIDPosition(s)Description
Binding site12NADP+ (UniProtKB | ChEBI)
Binding site19NADP+ (UniProtKB | ChEBI)
Binding site24NADP+ (UniProtKB | ChEBI)
Binding site56NADP+ (UniProtKB | ChEBI)
Binding site57NADP+ (UniProtKB | ChEBI)
Binding site58NADP+ (UniProtKB | ChEBI)
Binding site78NADP+ (UniProtKB | ChEBI)
Binding site79NADP+ (UniProtKB | ChEBI)
Binding site80NADP+ (UniProtKB | ChEBI)
Binding site117NADP+ (UniProtKB | ChEBI)
Binding site118NADP+ (UniProtKB | ChEBI)

GO annotations

AspectTerm
Cellular Componentmitochondrion
Molecular Functiondihydrofolate reductase activity
Molecular FunctionNADP binding
Biological Processdihydrofolate metabolic process
Biological Processfolic acid metabolic process
Biological Processone-carbon metabolic process
Biological Processtetrahydrofolate biosynthetic process

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    dihydrofolate reductase
  • EC number

Gene names

    • ORF names
      WUBG_00817

Organism names

  • Taxonomic identifier
  • Organism
  • Strain
    • NA
  • Taxonomic lineage
    Eukaryota > Metazoa > Ecdysozoa > Nematoda > Chromadorea > Rhabditida > Spirurina > Spiruromorpha > Filarioidea > Onchocercidae > Wuchereria

Accessions

  • Primary accession
    J9F199

Proteomes

Subcellular Location

Interaction

Protein-protein interaction databases

Family & Domains

Features

Showing features for domain.

TypeIDPosition(s)Description
Domain6-166DHFR

Sequence similarities

Belongs to the dihydrofolate reductase family.

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    172
  • Mass (Da)
    19,681
  • Last updated
    2012-10-31 v1
  • Checksum
    0EE8574C54DEC948
MTRTLHMNLIVAVDGCGGIGRNGGMPWFLPAEMARFAKLTTLTTDSGKKNAVIMGRKVWESIPPKFRPLKSRFNVVLSKKMKEESNENVVVARSFESAVSLLQDMENIETIWNIGGREMYITRVEGDFLADVFFPRVDYGRFIKSTESEEMHEEKGIKYRYEIYTIKTDKVA

Keywords

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
ADBV01000160
EMBL· GenBank· DDBJ
EJW88273.1
EMBL· GenBank· DDBJ
Genomic DNA

Genome annotation databases

Similar Proteins

Disclaimer

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