J5TN70 · J5TN70_TRIAS

Function

Caution

The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

Catalytic activity

Cofactor

Protein has several cofactor binding sites:
FAD (UniProtKB | Rhea| CHEBI:57692 )

FMN (UniProtKB | Rhea| CHEBI:58210 )

[3Fe-4S] cluster (UniProtKB | Rhea| CHEBI:21137 )

Note: Binds 1 [3Fe-4S] cluster.

Pathway

Amino-acid biosynthesis; L-glutamate biosynthesis via GLT pathway; L-glutamate from 2-oxoglutarate and L-glutamine (NAD+ route): step 1/1.
Energy metabolism; nitrogen metabolism.
Nitrogen metabolism.

Features

Showing features for binding site.

TypeIDPosition(s)Description
Binding site1115[3Fe-4S] cluster (UniProtKB | ChEBI)
Binding site1121[3Fe-4S] cluster (UniProtKB | ChEBI)
Binding site1126[3Fe-4S] cluster (UniProtKB | ChEBI)

GO annotations

AspectTerm
Molecular Function3 iron, 4 sulfur cluster binding
Molecular Functionflavin adenine dinucleotide binding
Molecular FunctionFMN binding
Molecular Functionglutamate synthase (NADH) activity
Molecular Functioniron ion binding
Biological Processglutamine metabolic process
Biological ProcessL-glutamate biosynthetic process

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    glutamate synthase (NADH)
  • EC number

Gene names

    • ORF names
      A1Q1_06977

Organism names

Accessions

  • Primary accession
    J5TN70

Proteomes

Organism-specific databases

Family & Domains

Features

Showing features for domain, region, compositional bias.

Type
IDPosition(s)Description
Domain1-375Glutamine amidotransferase type-2
Region874-903Disordered
Region2038-2099Disordered
Compositional bias2056-2074Polar residues

Sequence similarities

Belongs to the glutamate synthase family.

Keywords

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    2,099
  • Mass (Da)
    229,904
  • Last updated
    2012-10-31 v1
  • Checksum
    576D5594A769C27A
MTHRGATGADARDGDGAGVMTGIPHEFFVREAPHSFEAKIPAEGTYAVGNVFLDPQDWEAQQKVFEEVASKLGLRTLGWRHVPTDNSILGPAAKSKEPRIMQPFVVLRSHYGDGLESADGEFDEQYFQRQLYVLRKQASHRNDKFYICSLTPSNIVYKGQLSPVQVYNYFHDLNHALYSSHFALVHSRFSTNTFPSWDRAQPMRWAAHNGEINTVRGNKNWMRAREGHLKSEKFGNELELLYPIVEEGGSDSAAFDNVLELLVVNGVLTLPEAVMMMVPEAWQNNDLMEPEKKGFYAWAGSMMEPWDGPALFTFSDGRFCGANLDRNGLRPCRYIVTRDDIMICASEVGTISIDPATITQKGRLKPGRMLLVDTKEGRIVDDRELKMSVAKRQPFQAWYESQVIQLPDVVRRVQRFEDIGVKLDASPLASDPRVLAFGFTLEQLSMLMMPMVNEGHEALGSMGNDAALACVSNQARSIYDYFRQLFAQVTNPPIDPIREAIVMSLETMVGPEGNLLEMRSSQCHRLHLKSPILTIEEMNAIKSIQTSTSDWNAKVIDITFDKGEGLPGYHAALERVRQQALEAVNEGYKIVILSDRLTGPNRVPLSALLATGGVHHHLVKQKKRSDIAIMVDTAEAREVHHMCVLVGYGADAVCPWLMMEMIHKIEREGMAKDDQTAETLIDNYRKAINEGMLKVLSKMGVSTLASYKGAQLFEALGIHKEVVDECFVGTASRVQGATFDLLAMDAFEYHERAWPTRAISRIPGLPESGEYHYRNGSEKRINEPASVASLQDAVRQKNQAAYDSYSKNSHEAIKAATLRGMLDFDYDKAQSVPIDQVEPWNEIVRRCVTGAMSYGSISMEAHTTLAIAMNRLGGKSNTGEGGEDAERSLPIPGPGQGQEGTPYRHSMELQPEWDSRRSSIKQVASGRFGVTSNYLADSDELQIKMAQGAKPGEGGELPGHKVSASIGRTRHSTPGVTLVSPPPHHDIYSIEDLKQLIYDLKCANPRARVSVKLVSEVGVGVVASGVSKAKADHIVISGHDGGTGAAKWTSIKYAGLPWELGVAETHQTLVLNDLRGRVTVQTDGQIRTGRDIAIATLLGAEEWGFATTPLIAMGCIMMKACHKNTCPVGIATQDPELRAKFAGQPEQVINFFYYVIEELRAIMAKLGIRTINEMVGRADLLKVDESLRTPKTAHLDLSPILTPAKPPREGVATYRVRPQDHRLYVRLDNKFIDEAEPALSKGLPVEIDCDVVNTDRALGATLSYHVSKRYGEAGLPRDTIRINMKGSAGQSMGAFLAPGVTIELEGDANDYVGKGLSGGRIIAYPSKKAQFKAEENIIIGNVCFFGATSGQAFISGIAAERFAVRNSGATLVVEGTGDHGCEYMTGGRVVVLGLTGRNFAAGMSGGIAYVLDMSHSFAPKVNMGTVELGKVSDPHEIAELRSLIEEHRHYTGSEIADRVLRNFHHFLPMFVRIMPLDYKRVLEEQAAAALEEKKKQSHIDLIPSTTASQVDLAAPGVDPVLPGAMARLRLNKPSETDTPHTTPNSPRLEPAVLDMEDAMLDEDQYKARASKLDKVRGFMKYKRLNEAYRPPRKRVKDWKEISNRLSEAELKQQTARCMDCGLPFCSATNAGTGGGCPISNVIPKFNTLVFEGKWKEAWERLMLTNNFPEFTGRVCPAPCESSCVLGINELPVGIKSVEAAIIDKAWEMGWMVPNPPPQRTGKKVAIIGSGPAGLSAADQLNKAGHLVTVYERSSVIGGILSEGIPNMKLDKAVVKRRVQLMADEGVEFVTDTEVGINVEASAIKAGRDAVIIATGATIPRDLKIPGRDSQGVYMAMDFLTFNTKSLLASNHEDGNYINAKGLDVIVIGGGDTVRHGAKSVINFELLPQPPTARASNNPWEVMAYTQKDPREYCVLTKRFISDDQGNLTGIDTVRVEWENISGQWKMEEIKGTEKTYSCQLALLALGFLGPQKEVAEAFAVKQDARTNIQTPTGGFSTTVPGVFAAGDCRRGQSLVVWGINDGRQCAEEVDAFLMGSTRLPHQGGIPGRSWVPPRASKTPGQANGNASDSDSGLEPEVVSKSDAESDGFSAEAESEAVAA

Features

Showing features for compositional bias.

TypeIDPosition(s)Description
Compositional bias2056-2074Polar residues

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
ALBS01000047
EMBL· GenBank· DDBJ
EJT51746.1
EMBL· GenBank· DDBJ
Genomic DNA

Genome annotation databases

Similar Proteins

Disclaimer

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