J4GGP4 · J4GGP4_9APHY

  • Protein
    Phosphatidylethanolamine N-methyltransferase
  • Status
    UniProtKB unreviewed (TrEMBL)
  • Amino acids
  • Protein existence
    Inferred from homology
  • Annotation score
    3/5

Function

function

Catalyzes the first step of the methylation pathway of phosphatidylcholine biosynthesis, the SAM-dependent methylation of phosphatidylethanolamine (PE) to phosphatidylmonomethylethanolamine (PMME).

Caution

Lacks conserved residue(s) required for the propagation of feature annotation.

Catalytic activity

Pathway

Phospholipid metabolism; phosphatidylcholine biosynthesis.

GO annotations

AspectTerm
Cellular Componentendoplasmic reticulum membrane
Molecular Functionphosphatidylethanolamine N-methyltransferase activity
Biological Processmethylation
Biological Processphosphatidylcholine biosynthetic process

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    Phosphatidylethanolamine N-methyltransferase
  • EC number
  • Short names
    PE methyltransferase
    ; PEAMT
    ; PEMT

Gene names

    • ORF names
      FIBRA_08166

Organism names

  • Taxonomic identifier
  • Organism
  • Strain
    • TFFH 294
  • Taxonomic lineage
    Eukaryota > Fungi > Dikarya > Basidiomycota > Agaricomycotina > Agaricomycetes > Polyporales > Fibroporiaceae > Fibroporia

Accessions

  • Primary accession
    J4GGP4

Proteomes

Subcellular Location

Endoplasmic reticulum membrane
; Multi-pass membrane protein
Membrane
; Multi-pass membrane protein

Features

Showing features for transmembrane.

TypeIDPosition(s)Description
Transmembrane72-89Helical
Transmembrane95-117Helical
Transmembrane180-200Helical
Transmembrane206-225Helical
Transmembrane276-301Helical
Transmembrane465-487Helical
Transmembrane619-639Helical

Keywords

Interaction

Protein-protein interaction databases

Family & Domains

Features

Showing features for region, compositional bias.

TypeIDPosition(s)Description
Region1-20Disordered
Compositional bias328-363Polar residues
Region328-406Disordered
Compositional bias388-406Polar residues
Region924-945Disordered
Compositional bias928-945Basic and acidic residues

Sequence similarities

Keywords

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    996
  • Mass (Da)
    113,753
  • Last updated
    2012-10-31 v1
  • Checksum
    D4798ADDDCF1B1CA
MATAEPQSSVRQRRRNSAEVQAVTTDDNFNARKKEEVVWGKTPSGEVFRVPTTHDVLTALFHPAYPKSHLDLLNLGLLGLQLVLFAVLPRSIAKVFFLVYFAFWRAAYDLGLGWVLTKQSKRKWIVREVQRLGWLDENRQPAVRDWIREQLAGKMGKDYSFDELPLEYNTWLLFRQMVDIILLNDFLAYCMFAFTCFRVPEDLSIAVHVMRWIGGIALIAFNLWVKTEAHNVVKDYGWYWGDVFFQRGALVFDGVFELAPHPMYSVGYAGYYGLSLIIGSYFVLFVSLAAHAAQFGFLVFFENPHIERTYGQRKLLAHRSPVLAATSGRLGKTSSSHTRESSESSVFSSDLNTPSATEGESATETDEVLTETETETEFVHARQNRNKRRSTSSFGSNSTISDGTYRRSNSPLLSQHDFMNRYFRKDAIFFANVDILRASDFKLVLMIMYPLVTSFLPSLSNHGTLVLHFVHALAWCLFHSFGLGFVLRAQSENKFLVRHFLKHYHYPMKDHGRGALREAFDNWKSIYNLSMCMTYVSSICLAWKTYNIPQEWTVGNELLRHTLGAILIGLHVWATMEMYEVLGLFGWFFGDFFMEGFSAQLEYTGIYRYLNNPEVMSGAAFFGLALISGSKLVFTLAVVRHLSQWWFLSKVENPHMRKLYGDSLRNDAGFVKVIKKVANKNARLLESRAGRHAPEIRRVAREVKGTFEKVYEETADVVEEFLAKSRPRISEVVQDTKVLLQQSREKLVISRVANDLSSYDTAKYNVSIVPSSDGSSRFHLGEPIKVKWRAPLHHSRRDWIGIYRVGANKSSLVTKTSSLGMWVPVHDEEWDGDFPLSLNRPNRPDNDSENGEVVFRAGNLPWRTGRYEIRYHHDGKYNVLSLEGPIEIYVDKPNEVRFASVRTCLARIVPLCLDSDPSLIPLSCKNGQTESDDERDEASGRNPDDFRFWSERQAKRISVAIKQAFGVELDPEVIIADANLSSLADRIILSRELLAP

Features

Showing features for compositional bias.

TypeIDPosition(s)Description
Compositional bias328-363Polar residues
Compositional bias388-406Polar residues
Compositional bias928-945Basic and acidic residues

Keywords

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
HE797213
EMBL· GenBank· DDBJ
CCM05928.1
EMBL· GenBank· DDBJ
Genomic DNA

Genome annotation databases

Similar Proteins

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