J3QRU8 · J3QRU8_HUMAN

  • Protein
    GIT ArfGAP 1
  • Gene
    GIT1
  • Status
    UniProtKB unreviewed (TrEMBL)
  • Amino acids
  • Protein existence
    Evidence at protein level
  • Annotation score
    2/5

Function

GO annotations

all annotationsall molecular functionvirus receptor activitydna bindingrna bindingcytoskeletal motor activitycatalytic activitygtpase activitystructural molecule activitytransporter activitycytoskeletal protein bindinglipid bindingcyclase activityantioxidant activityoxidoreductase activitytransferase activityhydrolase activitylyase activityisomerase activityligase activityprotein tag activitycargo receptor activityhistone bindingprotein folding chaperonetranslation regulator activitynutrient reservoir activityreceptor ligand activitymolecular transducer activitymolecular adaptor activitytoxin activitycell adhesion mediator activitymolecular function regulator activityvirus coreceptor activitycatalytic activity, acting on a proteincatalytic activity, acting on dnacatalytic activity, acting on rnamolecular carrier activitytranscription regulator activitygeneral transcription initiation factor activitymolecular sensor activitymolecular sequestering activityatp-dependent activityother molecular functionall biological processmitotic cell cyclecytokinesiscytoplasmic translationimmune system processmuscle system processcirculatory system processrenal system processrespiratory system processcarbohydrate metabolic processgeneration of precursor metabolites and energydna replicationdna repairdna recombinationchromatin organizationdna-templated transcriptionregulation of dna-templated transcriptiontrna metabolic processprotein foldingprotein glycosylationamino acid metabolic processmodified amino acid metabolic processlipid metabolic processvitamin metabolic processsulfur compound metabolic processintracellular protein transportnucleocytoplasmic transportautophagyinflammatory responsemitochondrion organizationcytoskeleton organizationmicrotubule-based movementperoxisome organizationlysosome organizationchromosome segregationcell adhesionestablishment or maintenance of cell polarityprogrammed cell deathphotosynthesismrna metabolic processsnrna metabolic processvesicle-mediated transportreproductive processdigestive system processsignalingcell differentiationprotein catabolic processextracellular matrix organizationregulatory ncrna-mediated gene silencingtelomere organizationcell junction organizationwound healingribosome biogenesiscilium organizationanatomical structure developmentcell motilitynervous system processendocrine processprotein maturationtransmembrane transportnucleobase-containing small molecule metabolic processhepaticobiliary system processmembrane organizationprotein-containing complex assemblycell wall organization or biogenesisnitrogen cycle metabolic processprotein localization to plasma membranedefense response to other organismdetoxificationmeiotic nuclear divisionmitotic nuclear divisionmitochondrial gene expressioncarbohydrate derivative metabolic processother biological processall cellular componentnuclear chromosomeextracellular regionextracellular spacecell wallnucleusnuclear envelopenucleoplasmchromosomenucleolusmitochondrionlysosomeendosomevacuoleperoxisomeendoplasmic reticulumgolgi apparatuslipid dropletmicrotubule organizing centercytosolribosomecytoskeletonplasma membraneciliumplastidthylakoidexternal encapsulating structureextracellular matrixcytoplasmic vesicleorganelleother cellular component
Cell color indicative of number of GO terms
AspectTerm
Cellular Componentcytosol
Cellular Componentfocal adhesion
Cellular Componentmitochondrion
Molecular FunctionGTPase activator activity
Molecular Functionmetal ion binding
Biological Processbrain development
Biological Processregulation of ARF protein signal transduction

Keywords

Names & Taxonomy

Protein names

  • Submitted names
    • GIT ArfGAP 1

Gene names

    • Name
      GIT1

Organism names

  • Taxonomic identifier
  • Organism
  • Taxonomic lineage
    Eukaryota > Metazoa > Chordata > Craniata > Vertebrata > Euteleostomi > Mammalia > Eutheria > Euarchontoglires > Primates > Haplorrhini > Catarrhini > Hominidae > Homo

Accessions

  • Primary accession
    J3QRU8

Proteomes

Organism-specific databases

Subcellular Location

Disease & Variants

Variants

We now provide the "Disease & Variants" viewer in its own tab.

The viewer provides 635 variants from UniProt as well as other sources including ClinVar and dbSNP.

Go to variant viewer

Genetic variation databases

PTM/Processing

Features

Showing features for modified residue (large scale data).

TypeIDPosition(s)SourceDescription
Modified residue (large scale data)154PRIDEPhosphoserine
Modified residue (large scale data)359PRIDEPhosphoserine
Modified residue (large scale data)361PRIDEPhosphoserine
Modified residue (large scale data)362PRIDEPhosphoserine
Modified residue (large scale data)364PRIDEPhosphothreonine
Modified residue (large scale data)370PRIDEPhosphoserine
Modified residue (large scale data)383PRIDEPhosphotyrosine
Modified residue (large scale data)385PRIDEPhosphoserine
Modified residue (large scale data)388PRIDEPhosphoserine
Modified residue (large scale data)392PRIDEPhosphothreonine
Modified residue (large scale data)410PRIDEPhosphoserine
Modified residue (large scale data)413PRIDEPhosphoserine
Modified residue (large scale data)414PRIDEPhosphoserine
Modified residue (large scale data)417PRIDEPhosphoserine
Modified residue (large scale data)480PRIDEPhosphothreonine
Modified residue (large scale data)491PRIDEPhosphothreonine
Modified residue (large scale data)498PRIDEPhosphoserine
Modified residue (large scale data)508PRIDEPhosphoserine
Modified residue (large scale data)510PRIDEPhosphotyrosine
Modified residue (large scale data)514PRIDEPhosphoserine
Modified residue (large scale data)536PRIDEPhosphoserine
Modified residue (large scale data)545PRIDEPhosphotyrosine
Modified residue (large scale data)546PRIDEPhosphoserine
Modified residue (large scale data)554PRIDEPhosphotyrosine
Modified residue (large scale data)561PRIDEPhosphoserine
Modified residue (large scale data)563PRIDEPhosphoserine
Modified residue (large scale data)568PRIDEPhosphothreonine
Modified residue (large scale data)570PRIDEPhosphoserine
Modified residue (large scale data)571PRIDEPhosphoserine
Modified residue (large scale data)577PRIDEPhosphoserine
Modified residue (large scale data)581PRIDEPhosphoserine
Modified residue (large scale data)585PRIDEPhosphoserine
Modified residue (large scale data)588PRIDEPhosphoserine
Modified residue (large scale data)592PRIDEPhosphoserine
Modified residue (large scale data)596PRIDEPhosphoserine
Modified residue (large scale data)598PRIDEPhosphotyrosine
Modified residue (large scale data)601PRIDEPhosphothreonine
Modified residue (large scale data)670PRIDEPhosphoserine

Proteomic databases

Expression

Gene expression databases

Structure

Family & Domains

Features

Showing features for domain, repeat, compositional bias, region.

TypeIDPosition(s)Description
Domain1-124Arf-GAP
Repeat166-198ANK
Compositional bias354-371Polar residues
Region354-416Disordered
Compositional bias398-416Polar residues
Region471-501Disordered
Compositional bias474-488Pro residues
Region572-606Disordered

Keywords

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    694
  • Mass (Da)
    76,806
  • Last updated
    2012-10-03 v1
  • Checksum
    E2C8AF738B7FC913
MSRKGPRAEVCADCSAPDPGWASISRGVLVCDECCSVHRSLGRHISIVKHLRHSAWPPTLLQMVHTLASNGANSIWEHSLLDPAQVQSGRRKANPQDKVHPIKSEFIRAKYQMLAFVHKLPCRDDDGVTAKDLSKQLHSSVRTGNLETCLRLLSLGAQANFFHPEKGTTPLHVAAKAGQTLQAELLVVYGADPGSPDVNGRTPIDYARQAGHHELAERLVECQYELTDRLAFYLCGRKPDHKNGHYIIPQMADSLDLSELAKAAKKKLQALSNRLFEELAMDVYDEVDRRENDAVWLATQNHSTLVTERSAVPFLPVNPEYSATRNQGRQKLARFNAREFATLIIDILSEAKRRQQGKSLSSPTDNLELSLRSQSDLDDQHDYDSVASDEDTDQEPLRSTGATRSNRARSMDSSDLSDGAVTLQEYLELKKALATSEAKVQQLMKVNSSLSDELRRLQREIHKLQAENLQLRQPPGPVPTPPLPSERAEHTPMAPGGSTHRRDRQAFSMYEPGSALKPFGGPPGDELTTRLQPFHSTELEDDAIYSVHVPAGLYRIRKGVSASAVPFTPSSPLLSCSQEGSRHTSKLSRHGSGADSDYENTQSGDPLLGLEGKRFLELGKEEDFHPELESLDGDLDPGLPSTEDVILKTEQVTKNIQELLRAAQEFKHDSFVPCSEKIHLAVTEMASLFPKLVA

Computationally mapped potential isoform sequences

There are 8 potential isoforms mapped to this entry

View all
EntryEntry nameGene nameLength
Q9Y2X7GIT1_HUMANGIT1761
E7EVC2E7EVC2_HUMANGIT1147
K7EIX6K7EIX6_HUMANGIT152
K7EN79K7EN79_HUMANGIT1173
J3QL89J3QL89_HUMANGIT1177
J3QLH1J3QLH1_HUMANGIT1228
J3QQI0J3QQI0_HUMANGIT1149
A0A0C4DGN6A0A0C4DGN6_HUMANGIT1747

Features

Showing features for compositional bias.

TypeIDPosition(s)Description
Compositional bias354-371Polar residues
Compositional bias398-416Polar residues
Compositional bias474-488Pro residues

Keywords

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
AC104564
EMBL· GenBank· DDBJ
-Genomic DNA No translation available.

Genome annotation databases

Similar Proteins

Disclaimer

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