J2TLZ3 · J2TLZ3_9PSED
- ProteinProtein-L-isoaspartate O-methyltransferase
- Genepcm
- StatusUniProtKB unreviewed (TrEMBL)
- Organism
- Amino acids225 (go to sequence)
- Protein existenceInferred from homology
- Annotation score3/5
Function
function
Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and/or degradation of damaged proteins.
Catalytic activity
- [protein]-L-isoaspartate + S-adenosyl-L-methionine = [protein]-L-isoaspartate alpha-methyl ester + S-adenosyl-L-homocysteine
Features
Showing features for active site.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Active site | 74 | ||||
GO annotations
Aspect | Term | |
---|---|---|
Cellular Component | cytoplasm | |
Molecular Function | protein-L-isoaspartate (D-aspartate) O-methyltransferase activity | |
Biological Process | methylation | |
Biological Process | protein modification process | |
Biological Process | protein repair |
Keywords
- Molecular function
- Ligand
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended nameProtein-L-isoaspartate O-methyltransferase
- EC number
- Alternative names
Gene names
Organism names
- Organism
- Strain
- Taxonomic lineageBacteria > Pseudomonadota > Gammaproteobacteria > Pseudomonadales > Pseudomonadaceae > Pseudomonas
Accessions
- Primary accessionJ2TLZ3
Proteomes
Subcellular Location
Structure
Sequence
- Sequence statusComplete
- Length225
- Mass (Da)25,175
- Last updated2012-10-03 v1
- Checksum7B8615A00B700473
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
AKJG01000164 EMBL· GenBank· DDBJ | EJM80741.1 EMBL· GenBank· DDBJ | Genomic DNA |