I7FFU1 · I7FFU1_MYCS2
- Protein5-hydroxyisourate hydrolase
- StatusUniProtKB unreviewed (TrEMBL)
- Amino acids105 (go to sequence)
- Protein existenceInferred from homology
- Annotation score2/5
Function
function
Catalyzes the hydrolysis of 5-hydroxyisourate (HIU) to 2-oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline (OHCU).
Catalytic activity
- 5-hydroxyisourate + H2O = 5-hydroxy-2-oxo-4-ureido-2,5-dihydro-1H-imidazole-5-carboxylate + H+
Features
Showing features for binding site.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Binding site | 7 | substrate | |||
Binding site | 42 | substrate | |||
Binding site | 102 | substrate | |||
GO annotations
Aspect | Term | |
---|---|---|
Molecular Function | hydroxyisourate hydrolase activity | |
Biological Process | purine nucleobase metabolic process |
Keywords
- Molecular function
- Biological process
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended name5-hydroxyisourate hydrolase
- EC number
- Short namesHIU hydrolase ; HIUHase
Gene names
Organism names
- Strain
- Taxonomic lineageBacteria > Actinomycetota > Actinomycetes > Mycobacteriales > Mycobacteriaceae > Mycolicibacterium
Accessions
- Primary accessionI7FFU1
Proteomes
Interaction
Subunit
Homotetramer.
Structure
Family & Domains
Features
Showing features for domain.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Domain | 4-104 | Transthyretin/hydroxyisourate hydrolase | |||
Sequence similarities
Belongs to the transthyretin family. 5-hydroxyisourate hydrolase subfamily.
Phylogenomic databases
Family and domain databases
Sequence
- Sequence statusComplete
- Length105
- Mass (Da)11,201
- Last updated2017-05-10 v1
- MD5 Checksum8DD1D82007E3CEFE2C55021777AB1C12
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
CP001663 EMBL· GenBank· DDBJ | AFP37733.1 EMBL· GenBank· DDBJ | Genomic DNA |