Deciphering the biology of Mycobacterium tuberculosis from the complete genome sequence.Cole S.T., Brosch R., Parkhill J., Garnier T., Churcher C.M., Harris D.E., Gordon S.V., Eiglmeier K., Gas S.[...], Barrell B.G.View abstractCited forNUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]StrainATCC 25618 / H37RvCategoriesSequencesSourceUniProtKB reviewed (Swiss-Prot)PubMedEurope PMCNature 393:537-544 (1998)Cited in99+99+
No title available.Lew J.M.Cited forIDENTIFICATION, GENOME REANNOTATIONStrainATCC 25618 / H37RvCategoriesSequencesSourceUniProtKB reviewed (Swiss-Prot)Submission Submitted to EMBL/GenBank/DDBJ databases (DEC-2012)Cited in55
The genome sequence of Mycobacterium tuberculosis H37Rv.The Broad Institute Genome Sequencing PlatformGalagan J., Kreiswirth B., Dobos K., Fortune S., Fitzgerald M., Young S.K., Zeng Q., Gargeya S., Abouelleil A.[...], Birren B.Cited forNUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]StrainATCC 25618 / H37RvCategoriesSequencesSourceUniProtKB reviewed (Swiss-Prot)Submission Submitted to EMBL/GenBank/DDBJ databases (NOV-2013)Cited in51
The genome sequence of Mycobacterium tuberculosis H37Rv.The Broad Institute Genomics Platform, The Broad Institute Genome Sequencing Center for Infectious DiseaseEarl A.M., Kreiswirth B., Gomez J., Victor T., Desjardins C., Abeel T., Young S., Zeng Q., Gargeya S.[...], Birren B.Cited forNUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]StrainATCC 25618 / H37RvCategoriesSequencesSourceUniProtKB reviewed (Swiss-Prot)Submission Submitted to EMBL/GenBank/DDBJ databases (APR-2014)Cited in48
Proteogenomic analysis of Mycobacterium tuberculosis by high resolution mass spectrometry.Kelkar D.S., Kumar D., Kumar P., Balakrishnan L., Muthusamy B., Yadav A.K., Shrivastava P., Marimuthu A., Anand S.[...], Pandey A.View abstractCited forIDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]StrainATCC 25618 / H37RvCategoriesSequencesSourceUniProtKB reviewed (Swiss-Prot)PubMedEurope PMCMol. Cell. Proteomics 10:M111.011627-M111.011627 (2011)Cited in99+99+
In vitro cross-linking of Mycobacterium tuberculosis peptidoglycan by L,D- transpeptidases and inactivation of these enzymes by carbapenems.Cordillot M., Dubee V., Triboulet S., Dubost L., Marie A., Hugonnet J.E., Arthur M., Mainardi J.L.View abstractCited forFUNCTION, CATALYTIC ACTIVITY, SUBSTRATE SPECIFICITY, ACTIVITY REGULATIONStrainATCC 25618 / H37RvCategoriesFunctionSourceUniProtKB reviewed (Swiss-Prot)PubMedEurope PMCAntimicrob. Agents Chemother. 57:5940-5945 (2013)Cited in5
Structural basis for the inhibition of Mycobacterium tuberculosis L,D- transpeptidase by meropenem, a drug effective against extensively drug- resistant strains.Kim H.S., Kim J., Im H.N., Yoon J.Y., An D.R., Yoon H.J., Kim J.Y., Min H.K., Kim S.J.[...], Suh S.W.View abstractCited forX-RAY CRYSTALLOGRAPHY (1.79 ANGSTROMS) OF 131-408 OF APOENZYME AND IN COMPLEXES WITH MEROPENEM AND CALCIUM, ACTIVITY REGULATION, ACTIVE SITE, DOMAINStrainATCC 25618 / H37RvCategoriesFunction, Family & Domains, Interaction, StructureSourceUniProtKB reviewed (Swiss-Prot)PubMedEurope PMCActa Crystallogr. D 69:420-431 (2013)Cited in1
Structure of LdtMt2, an L,D-transpeptidase from Mycobacterium tuberculosis.Both D., Steiner E.M., Stadler D., Lindqvist Y., Schnell R., Schneider G.View abstractCited forX-RAY CRYSTALLOGRAPHY (1.46 ANGSTROMS) OF 55-408, DOMAINStrainATCC 25618 / H37RvCategoriesFamily & Domains, StructureSourceUniProtKB reviewed (Swiss-Prot)PubMedEurope PMCActa Crystallogr. D 69:432-441 (2013)Cited in1
Crystal structure of L,D-transpeptidase LdtMt2 in complex with meropenem reveals the mechanism of carbapenem against Mycobacterium tuberculosis.Li W.J., Li D.F., Hu Y.L., Zhang X.E., Bi L.J., Wang D.C.Cited forX-RAY CRYSTALLOGRAPHY (1.40 ANGSTROMS) OF 55-408 OF APOENZYME AND IN COMPLEX WITH MEROPENEM, MUTAGENESIS OF TYR-318StrainATCC 25618 / H37RvCategoriesInteraction, Phenotypes & Variants, StructureSourceUniProtKB reviewed (Swiss-Prot)PubMedEurope PMCCell Res. 23:728-731 (2013)Cited in1
alphabeta,alpha'beta'-Diepoxyketones are mechanism-based inhibitors of nucleophilic cysteine enzymes.de Munnik M., Lithgow J., Brewitz L., Christensen K.E., Bates R.H., Rodriguez-Miquel B., Schofield C.J.View abstractCategoriesStructureSourcePDB: 8BK3PubMedEurope PMCChem Commun (Camb) 59:12859-12862 (2023)Mapped to1
High-throughput screen with the l,d-transpeptidase Ldt<sub>Mt2</sub> of <i>Mycobacterium tuberculosis</i> reveals novel classes of covalently reacting inhibitors.de Munnik M., Lang P.A., De Dios Anton F., Cacho M., Bates R.H., Brem J., Rodriguez Miquel B., Schofield C.J.View abstractCategoriesStructureSourcePDB: 8A1J, PDB: 8A1K, PDB: 8A1L, PDB: 8A1M, PDB: 8A1N, PDB: 8A1O, PDB: 8AHOPubMedEurope PMCChem Sci 14:7262-7278 (2023)Mapped to1
Allosteric cooperation in beta-lactam binding to a non-classical transpeptidase.Ahmad N., Dugad S., Chauhan V., Ahmed S., Sharma K., Kachhap S., Zaidi R., Bishai W.R., Lamichhane G., Kumar P.View abstractCategoriesStructureSourcePDB: 7F71, PDB: 7F8PPubMedEurope PMCElife 11:e73055-e73055 (2022)Mapped to1
N-Thio-beta-lactams targeting L,D-transpeptidase-2, with activity against drug-resistant strains of Mycobacterium tuberculosis.Martelli G., Pessatti T.B., Steiner E.M., Cirillo M., Caso C., Bisognin F., Landreh M., Monte P.D., Giacomini D., Schnell R.View abstractCategoriesStructureSourcePDB: 7A0Z, PDB: 7A10, PDB: 7A11, PDB: 7A1C, PDB: 7A1EPubMedEurope PMCCell Chem Biol 28:1321-1332.e5 (2021)Mapped to1
Targeting the Mycobacterium tuberculosis transpeptidase Ldt<sub>Mt2</sub> with cysteine-reactive inhibitors including ebselen.de Munnik M., Lohans C.T., Lang P.A., Langley G.W., Malla T.R., Tumber A., Schofield C.J., Brem J.View abstractCategoriesStructureSourcePDB: 6RLG, PDB: 6RRMPubMedEurope PMCChem Commun (Camb) 55:10214-10217 (2019)Mapped to1
The 1-beta-methyl group confers a lower affinity of l,d-transpeptidase Ldtpisub>Mt2pi/sub> for ertapenem than for imipenem.Zhao F., Hou Y.J., Zhang Y., Wang D.C., Li D.F.View abstractCategoriesStructureSourcePDB: 6IYV, PDB: 6IYWPubMedEurope PMCBiochem Biophys Res Commun 510:254-260 (2019)Mapped to1
Structural insight into the inactivation of Mycobacterium tuberculosis non-classical transpeptidase Ldt<sub>Mt2</sub> by biapenem and tebipenem.Bianchet M.A., Pan Y.H., Basta L.A.B., Saavedra H., Lloyd E.P., Kumar P., Mattoo R., Townsend C.A., Lamichhane G.View abstractCategoriesStructureSourcePDB: 5D7H, PDB: 5DC2, PDB: 5DCCPubMedEurope PMCBMC Biochem 18:8-8 (2017)Mapped to2
Binding and processing of beta-lactam antibiotics by the transpeptidase Ldtpisub>Mt2pi/sub> from Mycobacterium tuberculosis.Steiner E.M., Schneider G., Schnell R.View abstractCategoriesStructureSourcePDB: 5LB1, PDB: 5LBGPubMedEurope PMCFEBS J 284:725-741 (2017)Mapped to1
Non-classical transpeptidases yield insight into new antibacterials.Kumar P., Kaushik A., Lloyd E.P., Li S.G., Mattoo R., Ammerman N.C., Bell D.T., Perryman A.L., Zandi T.A.[...], Lamichhane G.View abstractCategoriesStructureSourcePDB: 5DU7, PDB: 5DUJ, PDB: 5DVP, PDB: 5DZJ, PDB: 5DZP, PDB: 5E1G, PDB: 5E1I, PDB: 5K69PubMedEurope PMCNat Chem Biol 13:54-61 (2017)Mapped to2
Targeting the cell wall of Mycobacterium tuberculosis: structure and mechanism of L,D-transpeptidase 2.Erdemli S.B., Gupta R., Bishai W.R., Lamichhane G., Amzel L.M., Bianchet M.A.View abstractCategoriesStructureSourcePDB: 5DC2, PDB: 5DCCPubMedEurope PMCStructure 20:2103-2115 (2012)Cited in1Mapped to4