I6VHW8 · I6VHW8_9LAMI
- Protein1-deoxy-D-xylulose-5-phosphate reductoisomerase
- GeneDXR
- StatusUniProtKB unreviewed (TrEMBL)
- Organism
- Amino acids163 (go to sequence)
- Protein existenceInferred from homology
- Annotation score2/5
Function
Catalytic activity
- 2-C-methyl-D-erythritol 4-phosphate + NADP+ = 1-deoxy-D-xylulose 5-phosphate + H+ + NADPHThis reaction proceeds in the backward direction.
Cofactor
Protein has several cofactor binding sites:
Pathway
Isoprenoid biosynthesis; isopentenyl diphosphate biosynthesis via DXP pathway; isopentenyl diphosphate from 1-deoxy-D-xylulose 5-phosphate: step 1/6.
GO annotations
Aspect | Term | |
---|---|---|
Molecular Function | 1-deoxy-D-xylulose-5-phosphate reductoisomerase activity | |
Molecular Function | isomerase activity | |
Molecular Function | manganese ion binding | |
Molecular Function | NADPH binding | |
Biological Process | isopentenyl diphosphate biosynthetic process, methylerythritol 4-phosphate pathway involved in terpenoid biosynthetic process |
Keywords
- Molecular function
- Ligand
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended name1-deoxy-D-xylulose-5-phosphate reductoisomerase
- EC number
Gene names
Organism names
- Organism
- Strain
- Taxonomic lineageEukaryota > Viridiplantae > Streptophyta > Embryophyta > Tracheophyta > Spermatophyta > Magnoliopsida > eudicotyledons > Gunneridae > Pentapetalae > asterids > lamiids > Lamiales > Lamiaceae > Nepetoideae > Mentheae > Micromeria
Accessions
- Primary accessionI6VHW8
Structure
Family & Domains
Features
Showing features for domain.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Domain | 16-99 | 1-deoxy-D-xylulose 5-phosphate reductoisomerase C-terminal | ||||
Sequence: ILPADSEHSAIFQCIQGLPEGALRRIILTASGGAFRDLPVEKLKEVKVADALKHPNWNMGKKITVDSATLFNKGLEVIEAHYLF | ||||||
Domain | 131-161 | DXP reductoisomerase C-terminal | ||||
Sequence: LGWPDMRLPILYTLSWPERIYCSEITWPRLD |
Sequence similarities
Belongs to the DXR family.
Family and domain databases
Sequence
- Sequence statusFragment
- Length163
- Mass (Da)18,257
- Last updated2012-10-03 v1
- ChecksumE807C01B4BC2A22C
Features
Showing features for non-terminal residue.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Non-terminal residue | 1 | |||||
Sequence: G | ||||||
Non-terminal residue | 163 | |||||
Sequence: C |