I6UGW0 · I6UGW0_9MAGN
- ProteinNAD(P)H-quinone oxidoreductase subunit 5, chloroplastic
- GenendhF
- StatusUniProtKB unreviewed (TrEMBL)
- Organism
- Amino acids670 (go to sequence)
- Protein existenceInferred from homology
- Annotation score3/5
Function
function
NDH shuttles electrons from NAD(P)H:plastoquinone, via FMN and iron-sulfur (Fe-S) centers, to quinones in the photosynthetic chain and possibly in a chloroplast respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation, and thus conserves the redox energy in a proton gradient.
Catalytic activity
- a plastoquinone + (n+1) H+(in) + NADH = a plastoquinol + n H+(out) + NAD+
a plastoquinone RHEA-COMP:9562 + (n+1) H+ (in)CHEBI:15378+ CHEBI:57945 = a plastoquinol RHEA-COMP:9561 + n H+ (out)CHEBI:15378+ CHEBI:57540 - a plastoquinone + (n+1) H+(in) + NADPH = a plastoquinol + n H+(out) + NADP+
GO annotations
Aspect | Term | |
---|---|---|
Cellular Component | chloroplast thylakoid membrane | |
Cellular Component | mitochondrial respiratory chain complex I | |
Molecular Function | NADH dehydrogenase (ubiquinone) activity | |
Molecular Function | NADH dehydrogenase activity | |
Molecular Function | quinone binding | |
Biological Process | ATP synthesis coupled electron transport | |
Biological Process | electron transport coupled proton transport |
Keywords
- Molecular function
- Biological process
- Ligand
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended nameNAD(P)H-quinone oxidoreductase subunit 5, chloroplastic
- EC number
- Alternative names
Gene names
Encoded on
- Chloroplast
Organism names
- Organism
- Taxonomic lineageEukaryota > Viridiplantae > Streptophyta > Embryophyta > Tracheophyta > Spermatophyta > Magnoliopsida > Magnoliidae > Magnoliales > Annonaceae > Annonoideae > Uvarieae > Monanthotaxis
Accessions
- Primary accessionI6UGW0
Subcellular Location
UniProt Annotation
GO Annotation
Membrane ; Multi-pass membrane protein
Plastid, chloroplast thylakoid membrane ; Multi-pass membrane protein
Features
Showing features for transmembrane.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Transmembrane | 20-39 | Helical | ||||
Sequence: FPSVLLLSIVMVFSAHLSIY | ||||||
Transmembrane | 70-88 | Helical | ||||
Sequence: LSSIMSILITTVGITVLFY | ||||||
Transmembrane | 100-119 | Helical | ||||
Sequence: LRFFTSMSFFTISMLGLVTS | ||||||
Transmembrane | 125-145 | Helical | ||||
Sequence: IYIFWELVGMCSYLLIGFWFT | ||||||
Transmembrane | 157-177 | Helical | ||||
Sequence: FVTNRVGDFGLLLGILGFYWI | ||||||
Transmembrane | 197-217 | Helical | ||||
Sequence: NGVNCLFATLCAFLLFVGAIA | ||||||
Transmembrane | 238-259 | Helical | ||||
Sequence: ISALIHAATMVAAGIFLVARLF | ||||||
Transmembrane | 265-284 | Helical | ||||
Sequence: IPHIMWLISLVGIITVLLGA | ||||||
Transmembrane | 374-395 | Helical | ||||
Sequence: TTFYVGTLSLCGIPPLACFWSK | ||||||
Transmembrane | 407-429 | Helical | ||||
Sequence: PMFAIIAYSAAGLTAFYMFRIYL | ||||||
Transmembrane | 524-545 | Helical | ||||
Sequence: MLLPLLILFLFTLFVGSIGIPF | ||||||
Transmembrane | 579-601 | Helical | ||||
Sequence: FLINSIFSVSIACFGIFIASLFY |
Keywords
- Cellular component
PTM/Processing
Keywords
- PTM
Interaction
Subunit
NDH is composed of at least 16 different subunits, 5 of which are encoded in the nucleus.
Structure
Family & Domains
Features
Showing features for domain.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Domain | 53-103 | NADH-Ubiquinone oxidoreductase (complex I) chain 5 N-terminal | ||||
Sequence: WTINNDFSFEFGHLIDPLSSIMSILITTVGITVLFYSDNYMSHDQGYLRFF | ||||||
Domain | 119-419 | NADH:quinone oxidoreductase/Mrp antiporter membrane subunit | ||||
Sequence: STNLVQIYIFWELVGMCSYLLIGFWFTRPIAANACQKAFVTNRVGDFGLLLGILGFYWITGSFEFRELFEILNNLISNNGVNCLFATLCAFLLFVGAIAKSAQFPLHVWLPDAMEGPTPISALIHAATMVAAGIFLVARLFPLFRVIPHIMWLISLVGIITVLLGATLSLAQRDIKRGLAYSTMSQLGYIMLAPGIGSFRAALFHLITHAYSKALLFLGSGSVIHSMESIVGYSPDKSQNMVLMGGLTKYVPITKTTFYVGTLSLCGIPPLACFWSKDEILNDSWLYSPMFAIIAYSAAGL | ||||||
Domain | 426-667 | NADH:ubiquinone/plastoquinone oxidoreductase chloroplast chain 5 C-terminal | ||||
Sequence: RIYLLTFEGHLRVQFQNYSGTKNSSLYSIPIWGNEGMGLSNKNLPFLVINDNNNKERLSFFSNKVYQMDGNVRNPMRFFSTYSDNKDTSIYPHESDNTMLLPLLILFLFTLFVGSIGIPFERLGTGFDILSKWLIPQITFLQKDLNFSVDWYEFLINSIFSVSIACFGIFIASLFYGPVYSSFQNLDLINSFVKMSPKRIFSDRIKYGIYSWSYNRGYIDIFYATFFIKGIRRLALLTNFFD |
Sequence similarities
Belongs to the complex I subunit 5 family.
Keywords
- Domain
Family and domain databases
Sequence
- Sequence statusFragment
- Length670
- Mass (Da)75,742
- Last updated2012-10-03 v1
- Checksum77A59F78D5D1ED0A
Features
Showing features for non-terminal residue.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Non-terminal residue | 1 | |||||
Sequence: G | ||||||
Non-terminal residue | 670 | |||||
Sequence: I |