I3ZN84 · I3ZN84_HUMAN

  • Protein
    HLA-B alpha chain (B*5703GB)
  • Gene
    HLA-B
  • Status
    UniProtKB unreviewed (TrEMBL)
  • Amino acids
  • Protein existence
    Evidence at protein level
  • Annotation score
    3/5

Function

function

Involved in the presentation of foreign antigens to the immune system.

GO annotations

all annotationsall molecular functionvirus receptor activitydna bindingrna bindingcytoskeletal motor activitycatalytic activitygtpase activitystructural molecule activitytransporter activitycytoskeletal protein bindinglipid bindingcyclase activityantioxidant activityoxidoreductase activitytransferase activityhydrolase activitylyase activityisomerase activityligase activityprotein tag activitycargo receptor activityhistone bindingprotein folding chaperonetranslation regulator activitynutrient reservoir activityreceptor ligand activitymolecular transducer activitymolecular adaptor activitytoxin activitycell adhesion mediator activitymolecular function regulator activityvirus coreceptor activitycatalytic activity, acting on a proteincatalytic activity, acting on dnacatalytic activity, acting on rnamolecular carrier activitytranscription regulator activitygeneral transcription initiation factor activitymolecular sensor activitymolecular sequestering activityatp-dependent activityother molecular functionall biological processmitotic cell cyclecytokinesiscytoplasmic translationimmune system processmuscle system processcirculatory system processrenal system processrespiratory system processcarbohydrate metabolic processgeneration of precursor metabolites and energydna replicationdna repairdna recombinationchromatin organizationdna-templated transcriptionregulation of dna-templated transcriptiontrna metabolic processprotein foldingprotein glycosylationamino acid metabolic processmodified amino acid metabolic processlipid metabolic processvitamin metabolic processsulfur compound metabolic processintracellular protein transportnucleocytoplasmic transportautophagyinflammatory responsemitochondrion organizationcytoskeleton organizationmicrotubule-based movementperoxisome organizationlysosome organizationchromosome segregationcell adhesionestablishment or maintenance of cell polarityprogrammed cell deathphotosynthesismrna metabolic processsnrna metabolic processvesicle-mediated transportreproductive processdigestive system processsignalingcell differentiationprotein catabolic processextracellular matrix organizationregulatory ncrna-mediated gene silencingtelomere organizationcell junction organizationwound healingribosome biogenesiscilium organizationanatomical structure developmentcell motilitynervous system processendocrine processprotein maturationtransmembrane transportnucleobase-containing small molecule metabolic processhepaticobiliary system processmembrane organizationprotein-containing complex assemblycell wall organization or biogenesisnitrogen cycle metabolic processprotein localization to plasma membranedefense response to other organismdetoxificationmeiotic nuclear divisionmitotic nuclear divisionmitochondrial gene expressioncarbohydrate derivative metabolic processother biological processall cellular componentnuclear chromosomeextracellular regionextracellular spacecell wallnucleusnuclear envelopenucleoplasmchromosomenucleolusmitochondrionlysosomeendosomevacuoleperoxisomeendoplasmic reticulumgolgi apparatuslipid dropletmicrotubule organizing centercytosolribosomecytoskeletonplasma membraneciliumplastidthylakoidexternal encapsulating structureextracellular matrixcytoplasmic vesicleorganelleother cellular component
Cell color indicative of number of GO terms
AspectTerm
Cellular Componentcell surface
Cellular Componentearly endosome membrane
Cellular ComponentER to Golgi transport vesicle membrane
Cellular Componentlumenal side of endoplasmic reticulum membrane
Cellular ComponentMHC class I protein complex
Cellular Componentphagocytic vesicle membrane
Cellular Componentrecycling endosome membrane
Biological Processantigen processing and presentation of peptide antigen via MHC class I
Biological Processimmune response

Keywords

  • Biological process

Names & Taxonomy

Protein names

  • Submitted names
    • HLA-B alpha chain (B*5703GB)
    • MHC class I antigen

Gene names

    • Name
      HLA-B
    • Synonyms
      HLA-B*5703GB

Organism names

  • Taxonomic identifier
  • Organism
  • Taxonomic lineage
    Eukaryota > Metazoa > Chordata > Craniata > Vertebrata > Euteleostomi > Mammalia > Eutheria > Euarchontoglires > Primates > Haplorrhini > Catarrhini > Hominidae > Homo

Accessions

  • Primary accession
    I3ZN84

Subcellular Location

Features

Showing features for transmembrane.

TypeIDPosition(s)Description
Transmembrane308-330Helical

Keywords

  • Cellular component

PTM/Processing

Features

Showing features for signal, chain, disulfide bond.

TypeIDPosition(s)Description
Signal1-24
ChainPRO_501430527025-362
Disulfide bond125↔188
Disulfide bond227↔283

Keywords

Proteomic databases

Family & Domains

Features

Showing features for domain, region, compositional bias.

TypeIDPosition(s)Description
Domain209-295Ig-like
Region337-362Disordered
Compositional bias339-362Polar residues

Sequence similarities

Belongs to the MHC class I family.

Keywords

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    362
  • Mass (Da)
    40,299
  • Last updated
    2012-09-05 v1
  • Checksum
    45C98B4CD2F28B31
MRVTAPRTVLLLLWGAVALTETWAGSHSMRYFYTAMSRPGRGEPRFIAVGYVDDTQFVRFDSDAASPRMAPRAPWIEQEGPEYWDGETRNMKASAQTYRENLRIALRYYNQSEAGSHIIQVMYGCDVGPDGRLLRGHNQYAYDGKDYIALNEDLSSWTAADTAAQITQRKWEAARVAEQLRAYLEGLCVEWLRRYLENGKETLQRADPPKTHVTHHPISDHEATLRCWALGFYPAEITLTWQRDGEDQTQDTELVETRPAGDRTFQKWAAVVVPSGEEQRYTCHVQHEGLPKPLTLRWEPSSQSTVPIVGIVAGLAVLAVVVIGAVVAAVMCRRKSSGGKGGSYSQAACSDSAQGSDVSLTA

Features

Showing features for compositional bias.

TypeIDPosition(s)Description
Compositional bias339-362Polar residues

Keywords

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
JQ771786
EMBL· GenBank· DDBJ
AFL91488.1
EMBL· GenBank· DDBJ
Genomic DNA
KU528603
EMBL· GenBank· DDBJ
ALZ40818.1
EMBL· GenBank· DDBJ
Genomic DNA
KU319331
EMBL· GenBank· DDBJ
ANG08746.1
EMBL· GenBank· DDBJ
Genomic DNA
KU319332
EMBL· GenBank· DDBJ
ANG08747.1
EMBL· GenBank· DDBJ
Genomic DNA
KY000094
EMBL· GenBank· DDBJ
ASA39912.1
EMBL· GenBank· DDBJ
Genomic DNA
MH173405
EMBL· GenBank· DDBJ
AWM62451.1
EMBL· GenBank· DDBJ
Genomic DNA
Y09157
EMBL· GenBank· DDBJ
CAA70355.1
EMBL· GenBank· DDBJ
mRNA
MK938025
EMBL· GenBank· DDBJ
QDK62508.1
EMBL· GenBank· DDBJ
Genomic DNA
MK938045
EMBL· GenBank· DDBJ
QDK62528.1
EMBL· GenBank· DDBJ
Genomic DNA
MN016199
EMBL· GenBank· DDBJ
QDK62895.1
EMBL· GenBank· DDBJ
Genomic DNA
MN016311
EMBL· GenBank· DDBJ
QDK63006.1
EMBL· GenBank· DDBJ
Genomic DNA
MN016449
EMBL· GenBank· DDBJ
QDK63144.1
EMBL· GenBank· DDBJ
Genomic DNA
MN053492
EMBL· GenBank· DDBJ
QDK63236.1
EMBL· GenBank· DDBJ
Genomic DNA
MN136795
EMBL· GenBank· DDBJ
QDK63298.1
EMBL· GenBank· DDBJ
Genomic DNA
MT681781
EMBL· GenBank· DDBJ
QMI58748.1
EMBL· GenBank· DDBJ
Genomic DNA
MT681785
EMBL· GenBank· DDBJ
QMI58752.1
EMBL· GenBank· DDBJ
Genomic DNA
MT681786
EMBL· GenBank· DDBJ
QMI58753.1
EMBL· GenBank· DDBJ
Genomic DNA
LT599216
EMBL· GenBank· DDBJ
SBW38437.1
EMBL· GenBank· DDBJ
Genomic DNA
LS423034
EMBL· GenBank· DDBJ
SPS03132.1
EMBL· GenBank· DDBJ
Genomic DNA

Similar Proteins

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