I3XU21 · I3XU21_SULBS
- ProteinDiacylglycerol kinase
- StatusUniProtKB unreviewed (TrEMBL)
- Amino acids120 (go to sequence)
- Protein existenceInferred from homology
- Annotation score3/5
Function
function
Catalyzes the ATP-dependent phosphorylation of sn-l,2-diacylglycerol (DAG) to phosphatidic acid. Involved in the recycling of diacylglycerol produced as a by-product during membrane-derived oligosaccharide (MDO) biosynthesis.
Catalytic activity
- a 1,2-diacyl-sn-glycerol + ATP = a 1,2-diacyl-sn-glycero-3-phosphate + ADP + H+
Cofactor
Note: Mn2+, Zn2+, Cd2+ and Co2+ support activity to lesser extents.
Features
Showing features for binding site, active site.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Binding site | 15 | ATP (UniProtKB | ChEBI) | ||||
Sequence: Y | ||||||
Binding site | 27 | ATP (UniProtKB | ChEBI) | ||||
Sequence: E | ||||||
Binding site | 27 | a divalent metal cation (UniProtKB | ChEBI) | ||||
Sequence: E | ||||||
Active site | 68 | Proton acceptor | ||||
Sequence: E | ||||||
Binding site | 68 | substrate | ||||
Sequence: E | ||||||
Binding site | 75 | ATP (UniProtKB | ChEBI) | ||||
Sequence: E | ||||||
Binding site | 75 | a divalent metal cation (UniProtKB | ChEBI) | ||||
Sequence: E | ||||||
Binding site | 84-86 | ATP (UniProtKB | ChEBI) | ||||
Sequence: EYH | ||||||
Binding site | 93-94 | ATP (UniProtKB | ChEBI) | ||||
Sequence: KD | ||||||
Binding site | 97 | substrate | ||||
Sequence: S |
GO annotations
Aspect | Term | |
---|---|---|
Cellular Component | plasma membrane | |
Molecular Function | ATP binding | |
Molecular Function | ATP-dependent diacylglycerol kinase activity | |
Molecular Function | metal ion binding | |
Biological Process | phosphatidic acid biosynthetic process | |
Biological Process | phosphorylation |
Keywords
- Molecular function
- Biological process
- Ligand
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended nameDiacylglycerol kinase
- EC number
Gene names
Organism names
- Strain
- Taxonomic lineageBacteria > Campylobacterota > Epsilonproteobacteria > Campylobacterales > Sulfurospirillaceae > Sulfurospirillum
Accessions
- Primary accessionI3XU21
Proteomes
Subcellular Location
UniProt Annotation
GO Annotation
Cell inner membrane ; Multi-pass membrane protein
Features
Showing features for transmembrane.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Transmembrane | 30-47 | Helical | ||||
Sequence: FRLELILVLILSPLIYFV | ||||||
Transmembrane | 95-119 | Helical | ||||
Sequence: VGSAVVFLSIVVFVVVWFFCLFKAY |
Keywords
- Cellular component
Interaction
Protein-protein interaction databases
Structure
Sequence
- Sequence statusComplete
- Length120
- Mass (Da)13,827
- Last updated2012-09-05 v1
- Checksum27F43E5AA6205304
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
CP003333 EMBL· GenBank· DDBJ | AFL67445.1 EMBL· GenBank· DDBJ | Genomic DNA |