I3W9F6 · AQP1_RHIIR
- ProteinAquaporin-1
- GeneAQPF1
- StatusUniProtKB reviewed (Swiss-Prot)
- Amino acids276 (go to sequence)
- Protein existenceEvidence at protein level
- Annotation score3/5
Function
function
Water channel required to facilitate the transport of water across membranes (PubMed:23157494).
Stimulates plant drought tolerance by facilitating the transport of water from the arbuscular mycorrhiza fungus to host plants (PubMed:23157494).
Stimulates plant drought tolerance by facilitating the transport of water from the arbuscular mycorrhiza fungus to host plants (PubMed:23157494).
Catalytic activity
- H2O(in) = H2O(out)
Activity regulation
Polyethylene glycol (PEG) stimulates whereas glycerol inhibits the aquaporin activity.
GO annotations
all annotations | all molecular function | virus receptor activity | dna binding | rna binding | cytoskeletal motor activity | catalytic activity | gtpase activity | structural molecule activity | transporter activity | cytoskeletal protein binding | lipid binding | cyclase activity | antioxidant activity | oxidoreductase activity | transferase activity | hydrolase activity | lyase activity | isomerase activity | ligase activity | protein tag activity | cargo receptor activity | histone binding | protein folding chaperone | translation regulator activity | nutrient reservoir activity | receptor ligand activity | molecular transducer activity | molecular adaptor activity | toxin activity | cell adhesion mediator activity | molecular function regulator activity | virus coreceptor activity | catalytic activity, acting on a protein | catalytic activity, acting on dna | catalytic activity, acting on rna | molecular carrier activity | transcription regulator activity | general transcription initiation factor activity | molecular sensor activity | molecular sequestering activity | atp-dependent activity | other molecular function | all biological process | mitotic cell cycle | cytokinesis | cytoplasmic translation | immune system process | muscle system process | circulatory system process | renal system process | respiratory system process | carbohydrate metabolic process | generation of precursor metabolites and energy | dna replication | dna repair | dna recombination | chromatin organization | dna-templated transcription | regulation of dna-templated transcription | trna metabolic process | protein folding | protein glycosylation | amino acid metabolic process | modified amino acid metabolic process | lipid metabolic process | vitamin metabolic process | sulfur compound metabolic process | intracellular protein transport | nucleocytoplasmic transport | autophagy | inflammatory response | mitochondrion organization | cytoskeleton organization | microtubule-based movement | peroxisome organization | lysosome organization | chromosome segregation | cell adhesion | establishment or maintenance of cell polarity | programmed cell death | photosynthesis | mrna metabolic process | snrna metabolic process | vesicle-mediated transport | reproductive process | digestive system process | signaling | cell differentiation | protein catabolic process | extracellular matrix organization | regulatory ncrna-mediated gene silencing | telomere organization | cell junction organization | wound healing | ribosome biogenesis | cilium organization | anatomical structure development | cell motility | nervous system process | endocrine process | protein maturation | transmembrane transport | nucleobase-containing small molecule metabolic process | hepaticobiliary system process | membrane organization | protein-containing complex assembly | cell wall organization or biogenesis | nitrogen cycle metabolic process | protein localization to plasma membrane | defense response to other organism | detoxification | meiotic nuclear division | mitotic nuclear division | mitochondrial gene expression | carbohydrate derivative metabolic process | other biological process | all cellular component | nuclear chromosome | extracellular region | extracellular space | cell wall | nucleus | nuclear envelope | nucleoplasm | chromosome | nucleolus | mitochondrion | lysosome | endosome | vacuole | peroxisome | endoplasmic reticulum | golgi apparatus | lipid droplet | microtubule organizing center | cytosol | ribosome | cytoskeleton | plasma membrane | cilium | plastid | thylakoid | external encapsulating structure | extracellular matrix | cytoplasmic vesicle | organelle | other cellular component | |||
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Aspect | Term | |
---|---|---|
Cellular Component | plasma membrane | |
Molecular Function | water channel activity |
Keywords
- Biological process
Names & Taxonomy
Protein names
- Recommended nameAquaporin-1
Gene names
Organism names
- Taxonomic lineageEukaryota > Fungi > Fungi incertae sedis > Mucoromycota > Glomeromycotina > Glomeromycetes > Glomerales > Glomeraceae > Rhizophagus
Accessions
- Primary accessionI3W9F6
Organism-specific databases
Subcellular Location
UniProt Annotation
GO Annotation
Cell membrane ; Multi-pass membrane protein
Features
Showing features for topological domain, transmembrane.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Topological domain | 1-10 | Cytoplasmic | ||||
Sequence: MLDAEQKKNY | ||||||
Transmembrane | 11-31 | Helical | ||||
Sequence: VAGAFGEFVGTAYFLFMGVGG | ||||||
Topological domain | 32-46 | Extracellular | ||||
Sequence: AVNFLNNAAGSPLPG | ||||||
Transmembrane | 47-67 | Helical | ||||
Sequence: FAIPFCFGFSLFVNVFIWAPI | ||||||
Topological domain | 68-93 | Cytoplasmic | ||||
Sequence: SGGVFNPSITIALMATNPKDFPWYRG | ||||||
Transmembrane | 94-114 | Helical | ||||
Sequence: ILYIVSQFLGALFGSWLIDLI | ||||||
Topological domain | 115-133 | Extracellular | ||||
Sequence: QPEAPNAATLLADGVSVAQ | ||||||
Transmembrane | 134-154 | Helical | ||||
Sequence: GLFMEMFATSVLTMAVLILAG | ||||||
Topological domain | 155-159 | Cytoplasmic | ||||
Sequence: ERYGK | ||||||
Transmembrane | 160-180 | Helical | ||||
Sequence: YLAPFGIGMSLFISALCAGPY | ||||||
Topological domain | 181-204 | Extracellular | ||||
Sequence: TGASLNPARTLGPAIVANQYGRAH | ||||||
Transmembrane | 205-225 | Helical | ||||
Sequence: WIYYVGPTLGSLLAAGYWHIL | ||||||
Topological domain | 226-276 | Cytoplasmic | ||||
Sequence: RILNIDVVDLKNVLNKCKKCGKEDPRISLKHCEECLKDDPKPEKYDIESQN |
Keywords
- Cellular component
PTM/Processing
Features
Showing features for chain.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Chain | PRO_0000457436 | 1-276 | Aquaporin-1 | |||
Sequence: MLDAEQKKNYVAGAFGEFVGTAYFLFMGVGGAVNFLNNAAGSPLPGFAIPFCFGFSLFVNVFIWAPISGGVFNPSITIALMATNPKDFPWYRGILYIVSQFLGALFGSWLIDLIQPEAPNAATLLADGVSVAQGLFMEMFATSVLTMAVLILAGERYGKYLAPFGIGMSLFISALCAGPYTGASLNPARTLGPAIVANQYGRAHWIYYVGPTLGSLLAAGYWHILRILNIDVVDLKNVLNKCKKCGKEDPRISLKHCEECLKDDPKPEKYDIESQN |
Expression
Induction
Expression is increased significantly in arbuscule-enriched cortical cells and extraradical mycelia of maize roots under drought stress.
Structure
Family & Domains
Features
Showing features for motif.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Motif | 73-75 | NPA 1 | ||||
Sequence: NPS | ||||||
Motif | 186-188 | NPA 2 | ||||
Sequence: NPA |
Domain
Aquaporins contain two tandem repeats each containing three membrane-spanning domains and a pore-forming loop with the signature motif Asn-Pro-Ala (NPA) (Probable). AQPF1 has NPS/NPA motifs which is in accordance with the fungal aquaporins (NPx and NxA) (Probable).
Sequence similarities
Belongs to the MIP/aquaporin (TC 1.A.8) family.
Keywords
- Domain
Family and domain databases
Sequence
- Sequence statusComplete
- Length276
- Mass (Da)29,917
- Last updated2012-09-05 v1
- ChecksumD90130C823A41050