I3TY87 · I3TY87_ENTFD

Function

function

Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre-crRNA and tracrRNA of type II CRISPR loci if present in the organism.

Catalytic activity

  • Endonucleolytic cleavage to 5'-phosphomonoester.
    EC:3.1.26.3 (UniProtKB | ENZYME | Rhea)

Cofactor

Mg2+ (UniProtKB | Rhea| CHEBI:18420 )

Features

Showing features for binding site, active site.

123120406080100120140160180200220
TypeIDPosition(s)Description
Binding site51Mg2+ (UniProtKB | ChEBI)
Active site55
Binding site124Mg2+ (UniProtKB | ChEBI)
Active site127
Binding site127Mg2+ (UniProtKB | ChEBI)

GO annotations

AspectTerm
Cellular Componentcytoplasm
Molecular Functiondouble-stranded RNA binding
Molecular Functionmetal ion binding
Molecular Functionribonuclease III activity
Molecular FunctionrRNA binding
Biological ProcessmRNA processing
Biological Processregulation of gene expression
Biological ProcessrRNA processing
Biological ProcesstRNA processing

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    Ribonuclease 3
  • EC number
  • Alternative names
    • Ribonuclease III
      (RNase III
      )

Gene names

    • Name
      rnc
    • ORF names
      HMPREF0351_10101

Organism names

Accessions

  • Primary accession
    I3TY87

Proteomes

Subcellular Location

Keywords

Interaction

Subunit

Homodimer.

Family & Domains

Features

Showing features for domain.

TypeIDPosition(s)Description
Domain9-138RNase III
Domain164-231DRBM

Sequence similarities

Belongs to the ribonuclease III family.

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    231
  • Mass (Da)
    26,380
  • Last updated
    2012-09-05 v1
  • Checksum
    864AD26446D13A21
MWKMDNQLTKELKENYNIVFHDLNLLEQAFTHSSYVNEHRNLQLSDNERLEFLGDAVLELMVSQYLFRLYPHLPEGKLTKTRAAIVREDSLSKFAKECHFDQYVLLGKGEENSGGRTRPALLCDLFEAFLGALYLDQGFDTTHAFIEKVIFPKVKAGAFSHEMDHKTKLQEVLQKSGDVSIEYRLINEEGPAHERVFWIEVYVDDQLIGTGQGKSKKLAEQAAAENALAAL

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
CP003583
EMBL· GenBank· DDBJ
AFK57725.1
EMBL· GenBank· DDBJ
Genomic DNA

Genome annotation databases

Similar Proteins

Disclaimer

Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care. Our staff consists of biologists and biochemists that are not trained to give medical advice.
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