I3RFU8 · I3RFU8_9EURY

  • Protein
    ADP-specific phosphofructokinase
  • Gene
    pfkC
  • Status
    UniProtKB unreviewed (TrEMBL)
  • Amino acids
  • Protein existence
    Inferred from homology
  • Annotation score
    3/5

Function

function

Catalyzes the phosphorylation of fructose 6-phosphate to fructose 1,6-bisphosphate using ADP as the phosphate donor.

Catalytic activity

Cofactor

Mg2+ (UniProtKB | Rhea| CHEBI:18420 )

Note: Binds 1 Mg2+ ion per subunit.

Pathway

Carbohydrate degradation; glycolysis.

Features

Showing features for binding site, active site.

TypeIDPosition(s)Description
Binding site262Mg2+ (UniProtKB | ChEBI)
Binding site292Mg2+ (UniProtKB | ChEBI)
Active site435Proton acceptor
Binding site435Mg2+ (UniProtKB | ChEBI)

GO annotations

AspectTerm
Cellular Componentcytoplasm
Molecular FunctionADP-specific phosphofructokinase activity
Molecular Functionmagnesium ion binding
Molecular Functionphosphofructokinase activity
Biological Processfructose metabolic process
Biological Processglycolytic process

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    ADP-specific phosphofructokinase
  • EC number
  • Alternative names
    • ADP-dependent phosphofructokinase
      (ADP-Pfk
      )

Gene names

    • Name
      pfkC
    • ORF names
      Py04_1537

Organism names

  • Taxonomic identifier
  • Organism
  • Strain
    • ST04
  • Taxonomic lineage
    Archaea > Euryarchaeota > Thermococci > Thermococcales > Thermococcaceae > Pyrococcus

Accessions

  • Primary accession
    I3RFU8

Proteomes

Subcellular Location

Keywords

Interaction

Protein-protein interaction databases

Family & Domains

Sequence similarities

Belongs to the carbohydrate kinase PfkC family.

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    458
  • Mass (Da)
    52,405
  • Last updated
    2012-09-05 v1
  • Checksum
    F4D7A5E1500F8D80
MLDEVRKLSAYTAYNANVDAIVNLNTEIVQKLIEEFGEDEIKERIEEYPREIKEPLDFIARLIHALKTGKPMAVPLVNENMHRWFDDTFKYDMERIGGQAGIIANLLAGLKVNKVIAYTPFLPKRLAELFKPGVLYPVVEGGKLKLKPIQEAYREGDPLKVNRIFEFRKGMKFKLGNEIITVPHSGRFIVSSRFESISRIETRDELRPFLPEIGKLVDGAILSGYQGLRLQYSDGKDANYYLRKAKEDIRLLKEAGIKIHVEFASIQDRKLRKKVVNNIFPMVDSVGMDEAEIAYILSVLGYRDLADRIFLYNRIEDAILGGMIILDELNFEILQVHTIYYLMYITHRDNPLSEEELAKSLEFGTTLAAARASLGDISKPEDYRVGEEVPFNERSDYVRLRFEEAKQKLRMREYKVVIVPTKLVPNPVSTVGLGDTISTGTFLSYIALLKKHSKSLTF

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
CP003534
EMBL· GenBank· DDBJ
AFK23108.1
EMBL· GenBank· DDBJ
Genomic DNA

Genome annotation databases

Similar Proteins

Disclaimer

Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care. Our staff consists of biologists and biochemists that are not trained to give medical advice.
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