I3L4D8 · I3L4D8_HUMAN

  • Protein
    Serine/arginine repetitive matrix 2
  • Gene
    SRRM2
  • Status
    UniProtKB unreviewed (TrEMBL)
  • Amino acids
  • Protein existence
    Evidence at protein level
  • Annotation score
    1/5

Function

GO annotations

all annotationsall molecular functionvirus receptor activitydna bindingrna bindingcytoskeletal motor activitycatalytic activitygtpase activitystructural molecule activitytransporter activitycytoskeletal protein bindinglipid bindingcyclase activityantioxidant activityoxidoreductase activitytransferase activityhydrolase activitylyase activityisomerase activityligase activityprotein tag activitycargo receptor activityhistone bindingprotein folding chaperonetranslation regulator activitynutrient reservoir activityreceptor ligand activitymolecular transducer activitymolecular adaptor activitytoxin activitycell adhesion mediator activitymolecular function regulator activityvirus coreceptor activitycatalytic activity, acting on a proteincatalytic activity, acting on dnacatalytic activity, acting on rnamolecular carrier activitytranscription regulator activitygeneral transcription initiation factor activitymolecular sensor activitymolecular sequestering activityatp-dependent activityother molecular functionall biological processmitotic cell cyclecytokinesiscytoplasmic translationimmune system processmuscle system processcirculatory system processrenal system processrespiratory system processcarbohydrate metabolic processgeneration of precursor metabolites and energydna replicationdna repairdna recombinationchromatin organizationdna-templated transcriptionregulation of dna-templated transcriptiontrna metabolic processprotein foldingprotein glycosylationamino acid metabolic processmodified amino acid metabolic processlipid metabolic processvitamin metabolic processsulfur compound metabolic processintracellular protein transportnucleocytoplasmic transportautophagyinflammatory responsemitochondrion organizationcytoskeleton organizationmicrotubule-based movementperoxisome organizationlysosome organizationchromosome segregationcell adhesionestablishment or maintenance of cell polarityprogrammed cell deathphotosynthesismrna metabolic processsnrna metabolic processvesicle-mediated transportreproductive processdigestive system processsignalingcell differentiationprotein catabolic processextracellular matrix organizationregulatory ncrna-mediated gene silencingtelomere organizationcell junction organizationwound healingribosome biogenesiscilium organizationanatomical structure developmentcell motilitynervous system processendocrine processprotein maturationtransmembrane transportnucleobase-containing small molecule metabolic processhepaticobiliary system processmembrane organizationprotein-containing complex assemblycell wall organization or biogenesisnitrogen cycle metabolic processprotein localization to plasma membranedefense response to other organismdetoxificationmeiotic nuclear divisionmitotic nuclear divisionmitochondrial gene expressioncarbohydrate derivative metabolic processother biological processall cellular componentnuclear chromosomeextracellular regionextracellular spacecell wallnucleusnuclear envelopenucleoplasmchromosomenucleolusmitochondrionlysosomeendosomevacuoleperoxisomeendoplasmic reticulumgolgi apparatuslipid dropletmicrotubule organizing centercytosolribosomecytoskeletonplasma membraneciliumplastidthylakoidexternal encapsulating structureextracellular matrixcytoplasmic vesicleorganelleother cellular component
Cell color indicative of number of GO terms
AspectTerm
Cellular Componentnuclear speck

Names & Taxonomy

Subcellular Location

Keywords

  • Cellular component

Disease & Variants

Variants

We now provide the "Disease & Variants" viewer in its own tab.

The viewer provides 4,175 variants from UniProt as well as other sources including ClinVar and dbSNP.

Go to variant viewer

Genetic variation databases

PTM/Processing

Features

Showing features for modified residue (large scale data).

TypeIDPosition(s)SourceDescription
Modified residue (large scale data)9PRIDEPhosphothreonine
Modified residue (large scale data)111PRIDEPhosphothreonine
Modified residue (large scale data)142PRIDEPhosphoserine
Modified residue (large scale data)144PRIDEPhosphoserine
Modified residue (large scale data)145PRIDEPhosphotyrosine
Modified residue (large scale data)150PRIDEPhosphoserine
Modified residue (large scale data)177PRIDEPhosphoserine
Modified residue (large scale data)182PRIDEPhosphoserine
Modified residue (large scale data)248PRIDEPhosphoserine
Modified residue (large scale data)251PRIDEPhosphothreonine
Modified residue (large scale data)286PRIDEPhosphothreonine
Modified residue (large scale data)288PRIDEPhosphothreonine
Modified residue (large scale data)289PRIDEPhosphothreonine
Modified residue (large scale data)295PRIDEPhosphoserine
Modified residue (large scale data)297PRIDEPhosphoserine
Modified residue (large scale data)300PRIDEPhosphoserine
Modified residue (large scale data)311PRIDEPhosphoserine
Modified residue (large scale data)315PRIDEPhosphothreonine
Modified residue (large scale data)316PRIDEPhosphothreonine
Modified residue (large scale data)317PRIDEPhosphoserine
Modified residue (large scale data)318PRIDEPhosphothreonine
Modified residue (large scale data)322PRIDEPhosphoserine
Modified residue (large scale data)323PRIDEPhosphoserine
Modified residue (large scale data)326PRIDEPhosphothreonine
Modified residue (large scale data)328PRIDEPhosphothreonine
Modified residue (large scale data)332PRIDEPhosphoserine
Modified residue (large scale data)333PRIDEPhosphoserine
Modified residue (large scale data)346PRIDEPhosphoserine
Modified residue (large scale data)348PRIDEPhosphothreonine
Modified residue (large scale data)351PRIDEPhosphoserine
Modified residue (large scale data)353PRIDEPhosphoserine
Modified residue (large scale data)357PRIDEPhosphoserine
Modified residue (large scale data)358PRIDEPhosphoserine
Modified residue (large scale data)359PRIDEPhosphothreonine
Modified residue (large scale data)367PRIDEPhosphothreonine
Modified residue (large scale data)377PRIDEPhosphoserine
Modified residue (large scale data)383PRIDEPhosphothreonine
Modified residue (large scale data)384PRIDEPhosphothreonine
Modified residue (large scale data)387PRIDEPhosphoserine
Modified residue (large scale data)395PRIDEPhosphoserine
Modified residue (large scale data)398PRIDEPhosphoserine
Modified residue (large scale data)400PRIDEPhosphothreonine
Modified residue (large scale data)404PRIDEPhosphoserine
Modified residue (large scale data)408PRIDEPhosphoserine
Modified residue (large scale data)416PRIDEPhosphoserine
Modified residue (large scale data)417PRIDEPhosphoserine
Modified residue (large scale data)418PRIDEPhosphoserine
Modified residue (large scale data)420PRIDEPhosphoserine
Modified residue (large scale data)421PRIDEPhosphoserine
Modified residue (large scale data)424PRIDEPhosphoserine
Modified residue (large scale data)431PRIDEPhosphoserine
Modified residue (large scale data)435PRIDEPhosphoserine
Modified residue (large scale data)436PRIDEPhosphoserine
Modified residue (large scale data)437PRIDEPhosphoserine
Modified residue (large scale data)440PRIDEPhosphoserine
Modified residue (large scale data)449PRIDEPhosphoserine
Modified residue (large scale data)454PRIDEPhosphoserine
Modified residue (large scale data)455PRIDEPhosphoserine
Modified residue (large scale data)456PRIDEPhosphoserine
Modified residue (large scale data)458PRIDEPhosphothreonine
Modified residue (large scale data)459PRIDEPhosphoserine
Modified residue (large scale data)472PRIDEPhosphoserine
Modified residue (large scale data)476PRIDEPhosphothreonine
Modified residue (large scale data)484PRIDEPhosphoserine
Modified residue (large scale data)486PRIDEPhosphoserine
Modified residue (large scale data)506PRIDEPhosphoserine
Modified residue (large scale data)508PRIDEPhosphoserine
Modified residue (large scale data)510PRIDEPhosphoserine
Modified residue (large scale data)534PRIDEPhosphoserine
Modified residue (large scale data)536PRIDEPhosphoserine
Modified residue (large scale data)543PRIDEPhosphoserine
Modified residue (large scale data)745PRIDEPhosphoserine
Modified residue (large scale data)778PRIDEPhosphoserine
Modified residue (large scale data)780PRIDEPhosphoserine
Modified residue (large scale data)782PRIDEPhosphoserine
Modified residue (large scale data)783PRIDEPhosphoserine
Modified residue (large scale data)817PRIDEPhosphoserine
Modified residue (large scale data)818PRIDEPhosphoserine
Modified residue (large scale data)819PRIDEPhosphoserine
Modified residue (large scale data)820PRIDEPhosphoserine
Modified residue (large scale data)829PRIDEPhosphothreonine
Modified residue (large scale data)834PRIDEPhosphoserine
Modified residue (large scale data)837PRIDEPhosphoserine
Modified residue (large scale data)838PRIDEPhosphoserine
Modified residue (large scale data)839PRIDEPhosphoserine
Modified residue (large scale data)846PRIDEPhosphoserine
Modified residue (large scale data)848PRIDEPhosphothreonine
Modified residue (large scale data)854PRIDEPhosphoserine
Modified residue (large scale data)856PRIDEPhosphothreonine
Modified residue (large scale data)857PRIDEPhosphoserine
Modified residue (large scale data)864PRIDEPhosphoserine
Modified residue (large scale data)866PRIDEPhosphothreonine
Modified residue (large scale data)871PRIDEPhosphoserine
Modified residue (large scale data)875PRIDEPhosphoserine
Modified residue (large scale data)876PRIDEPhosphoserine
Modified residue (large scale data)883PRIDEPhosphoserine
Modified residue (large scale data)885PRIDEPhosphothreonine
Modified residue (large scale data)887PRIDEPhosphoserine
Modified residue (large scale data)890PRIDEPhosphoserine
Modified residue (large scale data)892PRIDEPhosphoserine
Modified residue (large scale data)894PRIDEPhosphoserine
Modified residue (large scale data)895PRIDEPhosphoserine
Modified residue (large scale data)901PRIDEPhosphoserine
Modified residue (large scale data)902PRIDEPhosphoserine
Modified residue (large scale data)903PRIDEPhosphothreonine
Modified residue (large scale data)908PRIDEPhosphoserine
Modified residue (large scale data)910PRIDEPhosphoserine
Modified residue (large scale data)912PRIDEPhosphoserine
Modified residue (large scale data)913PRIDEPhosphoserine
Modified residue (large scale data)914PRIDEPhosphoserine
Modified residue (large scale data)924PRIDEPhosphoserine
Modified residue (large scale data)931PRIDEPhosphoserine
Modified residue (large scale data)934PRIDEPhosphoserine
Modified residue (large scale data)935PRIDEPhosphoserine
Modified residue (large scale data)937PRIDEPhosphoserine
Modified residue (large scale data)950PRIDEPhosphoserine
Modified residue (large scale data)952PRIDEPhosphoserine
Modified residue (large scale data)954PRIDEPhosphoserine
Modified residue (large scale data)957PRIDEPhosphoserine
Modified residue (large scale data)961PRIDEPhosphoserine
Modified residue (large scale data)968PRIDEPhosphoserine
Modified residue (large scale data)970PRIDEPhosphoserine
Modified residue (large scale data)972PRIDEPhosphoserine
Modified residue (large scale data)973PRIDEPhosphoserine
Modified residue (large scale data)974PRIDEPhosphoserine
Modified residue (large scale data)983PRIDEPhosphothreonine
Modified residue (large scale data)988PRIDEPhosphoserine
Modified residue (large scale data)990PRIDEPhosphoserine
Modified residue (large scale data)992PRIDEPhosphoserine
Modified residue (large scale data)994PRIDEPhosphoserine
Modified residue (large scale data)996PRIDEPhosphotyrosine
Modified residue (large scale data)1008PRIDEPhosphoserine
Modified residue (large scale data)1010PRIDEPhosphoserine
Modified residue (large scale data)1012PRIDEPhosphoserine

Proteomic databases

Expression

Gene expression databases

Structure

Family & Domains

Features

Showing features for region, compositional bias, domain.

TypeIDPosition(s)Description
Region102-121Disordered
Region141-1018Disordered
Compositional bias209-256Basic residues
Compositional bias264-295Polar residues
Compositional bias311-331Polar residues
Compositional bias332-350Basic and acidic residues
Compositional bias380-402Polar residues
Compositional bias409-438Polar residues
Compositional bias462-533Basic residues
Compositional bias546-719Basic residues
Domain563-682Spt5 C-terminal
Compositional bias758-873Polar residues
Compositional bias886-997Polar residues

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    1,018
  • Mass (Da)
    113,662
  • Last updated
    2012-07-11 v1
  • Checksum
    3EBD799482054207
MYNGIGLPTPRGSGTNGYVQRNLSLVRGRRGERPDYKGEEELRRLEAALVKRPNPDILDHERKRRVELRCLELEEMMEEQGYEEQQIQEKVATFRLMLLEKDVNPGGKEETPGQRPAVTETHQLAELNEKKNERLRAAFGISDSYVDGSSFDPQRRAREAKQPAPEPPKPYSLVRESSSSRSPTPKQKKKKKKKDRGRRSESSSPRRERKKSSKKKKHRSESESKKRKHRSPTPKSKRKSKDKKRKRSRSTTPAPKSRRAHRSTSADSASSSDTSRSRSRSAAAKTHTTALAGRSPSPASGRRGEGDAPFSEPGTTSTQRPSSPETATKQPSSPYEDKDKDKKEKSATRPSPSPERSSTGPEPPAPTPLLAERHGGSPQPLATTPLSQEPVNPPSEASPTRDRSPPKSPEKLPQSSSSESSPPSPQPTKVSRHASSSPESPKPAPAPGSHREISSSPTSKNRSHGRAKRDKSHSHTPSRRMGRSRSPATAKRGRSRSRTPTKRGHSRSRSPQWRRSRSAQRWGRSRSPQRRGRSRSPQRPGWSRSRNTQRRGRSRSARRGRSHSRSPATRGRSRSRTPARRGRSRSRTPARRRSRSRTPTRRRSRSRTPARRGRSRSRTPARRRSRTRSPVRRRSRSRSPARRSGRSRSRTPARRGRSRSRTPARRGRSRSRTPARRSGRSRSRTPARRGRSRSRTPRRGRSRSRSLVRRGRSHSRTPQRRGRSGSSSERKNKSRTSQRRSRSNSSPEMKKSRISSRRSRSLSSPRSKAKSRLSLRRSLSGSSPCPKQKSQTPPRRSRSGSSQPKAKSRTPPRRSRSSSSPPPKQKSKTPSRQSHSSSSPHPKVKSGTPPRQGSITSPQANEQSVTPQRRSCFESSPDPELKSRTPSRHSCSGSSPPRVKSSTPPRQSPSRSSSPQPKVKAIISPRQRSHSGSSSPSPSRVTSRTTPRRSRSVSPCSNVESRLLPRYSHSGSSSPDTKVKPETPPRQSHSGSISPYPKVKAQTPPGPSLSGSKSPCPQ

Computationally mapped potential isoform sequences

There are 8 potential isoforms mapped to this entry

View all
EntryEntry nameGene nameLength
Q9UQ35SRRM2_HUMANSRRM22752
I3L4U6I3L4U6_HUMANSRRM278
I3L3Q8I3L3Q8_HUMANSRRM21187
A0A087X1W1A0A087X1W1_HUMANSRRM2251
I3L1I8I3L1I8_HUMANSRRM2297
I3L182I3L182_HUMANSRRM2895
I3L0N7I3L0N7_HUMANSRRM2115
A0A994J493A0A994J493_HUMANSRRM2176

Features

Showing features for compositional bias.

TypeIDPosition(s)Description
Compositional bias209-256Basic residues
Compositional bias264-295Polar residues
Compositional bias311-331Polar residues
Compositional bias332-350Basic and acidic residues
Compositional bias380-402Polar residues
Compositional bias409-438Polar residues
Compositional bias462-533Basic residues
Compositional bias546-719Basic residues
Compositional bias758-873Polar residues
Compositional bias886-997Polar residues

Keywords

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
AC092117
EMBL· GenBank· DDBJ
-Genomic DNA No translation available.

Genome annotation databases

Similar Proteins

Disclaimer

Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care. Our staff consists of biologists and biochemists that are not trained to give medical advice.
We'd like to inform you that we have updated our Privacy Notice to comply with Europe’s new General Data Protection Regulation (GDPR) that applies since 25 May 2018.
FeedbackHelp