I1IUJ6 · C90A1_BRADI

Function

function

Involved in reduction steps of the biosynthesis of plant campesterol-derivative steroids, ending to castasterone (CS) but missing brassinolide (BL) (PubMed:32146811).
Catalyzes the conversion of (22S)-22-hydroxycampesterol (22-hydroxyCR, 22-OHCR) to (22S,24R)-22-hydroxyergost-4-en-3-one (22-hydroxy-campesta-4-en-3-one, 22-OH-4-en-3-one) and of 6-deoxoteasterone (6-deoxoTE) to 3-dehydro-6-deoxoteasterone (6-deoxo3DT, 6-deoxo3DHT) (PubMed:32146811).

Catalytic activity

Cofactor

heme (UniProtKB | Rhea| CHEBI:30413 )

Pathway

Plant hormone biosynthesis; brassinosteroid biosynthesis.

Features

Showing features for binding site.

TypeIDPosition(s)Description
Binding site447Fe (UniProtKB | ChEBI) of heme (UniProtKB | ChEBI); axial binding residue

GO annotations

AspectTerm
Cellular Componentmembrane
Molecular Functionheme binding
Molecular Functioniron ion binding
Molecular Functionmonooxygenase activity
Molecular Functionoxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen
Biological Processanther wall tapetum cell differentiation
Biological Processbrassinosteroid biosynthetic process
Biological Processbrassinosteroid homeostasis
Biological Processpollen exine formation
Biological Processpositive regulation of flower development
Biological Processresponse to UV-B
Biological Processsterol metabolic process

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    3beta,22alpha-dihydroxysteroid 3-dehydrogenase
  • EC number
  • Alternative names
    • (22S,24R)-22-hydroxyergost-4-en-3-one synthase
    • 3-dehydro-6-deoxoteasterone synthase
    • Cytochrome P450 90A1
      (BdCYP90A1
      )

Gene names

    • Name
      CYP90A1
    • Ordered locus names
      BRADI_4g43110v3

Organism names

Accessions

  • Primary accession
    I1IUJ6

Proteomes

Genome annotation databases

Subcellular Location

Membrane
; Single-pass membrane protein

Features

Showing features for transmembrane.

TypeIDPosition(s)Description
Transmembrane5-25Helical

Keywords

PTM/Processing

Features

Showing features for chain.

TypeIDPosition(s)Description
ChainPRO_00004553061-4983beta,22alpha-dihydroxysteroid 3-dehydrogenase

Interaction

Protein-protein interaction databases

Structure

Family & Domains

Features

Showing features for region.

TypeIDPosition(s)Description
Region257-277Disordered

Sequence similarities

Belongs to the cytochrome P450 family.

Keywords

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    498
  • Mass (Da)
    55,778
  • Last updated
    2012-06-13 v1
  • Checksum
    EE47942BE1266032
MENAGALQLLSAAAAAVAVVVVVALRWLLARRAAGGWKQRPRLPPGSTGLPLIGETLRLISAYKTPDPEPFIDERVARHGGVFTTHVFGERTVFSADPAFNRLLLAAEGRAVDCSYPSSITTLLGARSLLLTRGAAHKRLHSLTLTRLGRPASPPLLAHIDRLVLDTMRHWEPAATVRLLDEAKKITFNLTVKQLVSIDPGPWTESLRREYVKLIDGFFSIPFPFASLLPFTTYGQALKSRKKVAGALREVIRKRMEERGEESGATEEAESKREKKDMVEELLQAEGGSFSEEEMVDFCLSLLVAGYETTSVLMTVAVKFLTETPAALAQLKEEHENMTNMKGENQPLEWSDYKSMTFTQCVINETLRVANIISGVFRRANTDIHFKGYTIPKGCKIFASFRAVHLNNDHYENARTFDPWRWQSNHKLQNEVGANLFTPFGGGPRLCPGYELARVVISVFLHHLVMRFSWEAAEEDRLVFFPTTRTLKGYPINLRQRS

Keywords

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
CM000883
EMBL· GenBank· DDBJ
KQJ92356.1
EMBL· GenBank· DDBJ
Genomic DNA

Genome annotation databases

Similar Proteins

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