I0HU65 · I0HU65_RUBGI
- ProteintRNA-specific adenosine deaminase
- GenetadA
- StatusUniProtKB unreviewed (TrEMBL)
- Amino acids188 (go to sequence)
- Protein existenceInferred from homology
- Annotation score2/5
Function
function
Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2).
Catalytic activity
- adenosine34 in tRNA + H2O + H+ = inosine34 in tRNA + NH4+
RHEA-COMP:10373 CHEBI:74411
Position: 34+ CHEBI:15377 + CHEBI:15378 = RHEA-COMP:10374 CHEBI:82852
Position: 34+ CHEBI:28938
Cofactor
Note: Binds 1 zinc ion per subunit.
Features
Showing features for binding site, active site.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Binding site | 64 | Zn2+ (UniProtKB | ChEBI); catalytic | |||
Active site | 66 | Proton donor | |||
Binding site | 94 | Zn2+ (UniProtKB | ChEBI); catalytic | |||
Binding site | 97 | Zn2+ (UniProtKB | ChEBI); catalytic | |||
GO annotations
Aspect | Term | |
---|---|---|
Molecular Function | tRNA-specific adenosine-34 deaminase activity | |
Molecular Function | zinc ion binding | |
Biological Process | tRNA wobble adenosine to inosine editing |
Keywords
- Molecular function
- Biological process
- Ligand
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended nametRNA-specific adenosine deaminase
- EC number
Gene names
Organism names
- Strain
- Taxonomic lineageBacteria > Pseudomonadota > Betaproteobacteria > Burkholderiales > Sphaerotilaceae > Rubrivivax
Accessions
- Primary accessionI0HU65
Proteomes
Interaction
Structure
Family & Domains
Features
Showing features for domain.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Domain | 9-140 | CMP/dCMP-type deaminase | |||
Sequence similarities
Belongs to the cytidine and deoxycytidylate deaminase family. ADAT2 subfamily.
Phylogenomic databases
Family and domain databases
Sequence
- Sequence statusComplete
- Length188
- Mass (Da)20,471
- Last updated2012-06-13 v1
- MD5 ChecksumB55F53EB01FE23647FC8D38182E9BC6E
Keywords
- Technical term
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
AP012320 EMBL· GenBank· DDBJ | BAL96552.1 EMBL· GenBank· DDBJ | Genomic DNA |