I0BI61 · I0BI61_9BACL
- ProteinIsopentenyl-diphosphate delta-isomerase
- Genefni
- StatusUniProtKB unreviewed (TrEMBL)
- Organism
- Amino acids352 (go to sequence)
- Protein existenceInferred from homology
- Annotation score3/5
Function
function
Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP).
Catalytic activity
- isopentenyl diphosphate = dimethylallyl diphosphate
Cofactor
Protein has several cofactor binding sites:
Features
Showing features for binding site.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Binding site | 55-57 | FMN (UniProtKB | ChEBI) | ||||
Sequence: AMT | ||||||
Binding site | 85 | FMN (UniProtKB | ChEBI) | ||||
Sequence: S | ||||||
Binding site | 114 | FMN (UniProtKB | ChEBI) | ||||
Sequence: N | ||||||
Binding site | 144 | substrate | ||||
Sequence: Q | ||||||
Binding site | 145 | Mg2+ (UniProtKB | ChEBI) | ||||
Sequence: E | ||||||
Binding site | 176 | FMN (UniProtKB | ChEBI) | ||||
Sequence: K | ||||||
Binding site | 206 | FMN (UniProtKB | ChEBI) | ||||
Sequence: T | ||||||
Binding site | 277-278 | FMN (UniProtKB | ChEBI) | ||||
Sequence: AG |
GO annotations
Aspect | Term | |
---|---|---|
Cellular Component | cytoplasm | |
Molecular Function | FMN binding | |
Molecular Function | isopentenyl-diphosphate delta-isomerase activity | |
Molecular Function | magnesium ion binding | |
Molecular Function | NADPH binding | |
Molecular Function | oxidoreductase activity | |
Biological Process | isoprenoid biosynthetic process |
Keywords
- Molecular function
- Biological process
- Ligand
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended nameIsopentenyl-diphosphate delta-isomerase
- EC number
- Short namesIPP isomerase
- Alternative names
Gene names
Organism names
- Organism
- Strain
- Taxonomic lineageBacteria > Bacillota > Bacilli > Bacillales > Paenibacillaceae > Paenibacillus
Accessions
- Primary accessionI0BI61
Proteomes
Subcellular Location
Interaction
Subunit
Homooctamer. Dimer of tetramers.
Structure
Family & Domains
Features
Showing features for domain.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Domain | 159-319 | FMN-dependent dehydrogenase | ||||
Sequence: LERIHTIVEGVGVPVIVKEVGFGMVRESAERLLQTGAAAIDVGGAGGTNFAAIENARRARPMEWLNDWGCPTAIALLEVLEARPGTEGRSTPVIATGGITGALDAAKALVLGASAVGMAGAMLRVQREEGTEALIGFIESLHAELRLVMTALGASTVEELN |
Sequence similarities
Belongs to the IPP isomerase type 2 family.
Phylogenomic databases
Family and domain databases
Sequence
- Sequence statusComplete
- Length352
- Mass (Da)37,171
- Last updated2012-06-13 v1
- Checksum98E2FB01C212FF34
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
CP003422 EMBL· GenBank· DDBJ | AFH62058.1 EMBL· GenBank· DDBJ | Genomic DNA |