I0BI61 · I0BI61_9BACL

Function

function

Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP).

Caution

Lacks conserved residue(s) required for the propagation of feature annotation.

Catalytic activity

Cofactor

Protein has several cofactor binding sites:
FMN (UniProtKB | Rhea| CHEBI:58210 )

Mg2+ (UniProtKB | Rhea| CHEBI:18420 )

NADPH (UniProtKB | Rhea| CHEBI:57783 )

Features

Showing features for binding site.

TypeIDPosition(s)Description
Binding site55-57FMN (UniProtKB | ChEBI)
Binding site85FMN (UniProtKB | ChEBI)
Binding site114FMN (UniProtKB | ChEBI)
Binding site144substrate
Binding site145Mg2+ (UniProtKB | ChEBI)
Binding site176FMN (UniProtKB | ChEBI)
Binding site206FMN (UniProtKB | ChEBI)
Binding site277-278FMN (UniProtKB | ChEBI)

GO annotations

AspectTerm
Cellular Componentcytoplasm
Molecular FunctionFMN binding
Molecular Functionisopentenyl-diphosphate delta-isomerase activity
Molecular Functionmagnesium ion binding
Molecular FunctionNADPH binding
Molecular Functionoxidoreductase activity
Biological Processisoprenoid biosynthetic process

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    Isopentenyl-diphosphate delta-isomerase
  • EC number
  • Short names
    IPP isomerase
  • Alternative names
    • Isopentenyl diphosphate:dimethylallyl diphosphate isomerase
    • Isopentenyl pyrophosphate isomerase
    • Type 2 isopentenyl diphosphate isomerase
      (IDI-2
      )

Gene names

    • Name
      fni
    • ORF names
      B2K_15240

Organism names

Accessions

  • Primary accession
    I0BI61

Proteomes

Subcellular Location

Keywords

Interaction

Subunit

Homooctamer. Dimer of tetramers.

Family & Domains

Features

Showing features for domain.

TypeIDPosition(s)Description
Domain159-319FMN-dependent dehydrogenase

Sequence similarities

Belongs to the IPP isomerase type 2 family.

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    352
  • Mass (Da)
    37,171
  • Last updated
    2012-06-13 v1
  • Checksum
    98E2FB01C212FF34
MEHVHHALQQGISGAQGFRDIRLLPNCLPGISSDRISLVTGIGELTMSSPILINAMTGGARETEEINRELAAAARETGLAMAVGSQMSALKNPEVASSYRIVRQVNPEGIIFGNLGSEATLDQAKRAVEMLRADALQIHLNVMQELIMPEGDRDFTGMLERIHTIVEGVGVPVIVKEVGFGMVRESAERLLQTGAAAIDVGGAGGTNFAAIENARRARPMEWLNDWGCPTAIALLEVLEARPGTEGRSTPVIATGGITGALDAAKALVLGASAVGMAGAMLRVQREEGTEALIGFIESLHAELRLVMTALGASTVEELNLMPAVITGDTAQWCSARSIDIRKFAGRSGFAAR

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
CP003422
EMBL· GenBank· DDBJ
AFH62058.1
EMBL· GenBank· DDBJ
Genomic DNA

Genome annotation databases

Similar Proteins

Disclaimer

Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care. Our staff consists of biologists and biochemists that are not trained to give medical advice.
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